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Atopy as a Factor in the Prognosis of Hand Dermatitis

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Kanerva’s Occupational Dermatology

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Abstract

The 1-year period prevalence of hand eczema is about 10% in adults in the general population. More females than males are affected and the disease is most frequent at young ages. These differences in prevalence are mainly considered to be related to differences in skin irritant exposure. The origin of hand eczema is often multifactorial, with exogenous and endogenous factors contributing. Hand eczema has an unfavorable prognosis. Persistent symptoms are found in a large proportion of individuals with hand eczema in follow-up studies. The condition tends to have a chronic, often relapsing, course. Atopic dermatitis is a major risk factor for hand eczema. At least half of the people with moderate to severe atopic dermatitis in childhood have hand eczema as adults. In population-based studies, a threefold higher prevalence of hand eczema is usually found among people with atopy than people without. Atopy is found to have a negative influence on the prognosis of hand eczema in most follow-up studies. This applies to hand eczema cohorts from the general population, patients from dermatology clinics, and patients with occupational skin disease.

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Authors and Affiliations

  1. Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

    Birgitta Meding

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  1. Birgitta Meding
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Correspondence to Birgitta Meding .

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Editors and Affiliations

  1. Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany

    Swen Malte John

  2. National Allergy Research Centre, Department of Dermatology and Allergy, Herlev-Gentofte University Hospital, Hellerup, Hellerup, Denmark

    Jeanne Duus Johansen

  3. Department of Dermatology and Allergology, VU University Medical Center, Amsterdam, The Netherlands

    Thomas Rustemeyer

  4. Department of Dermatology, University Hospital Jena, Jena, Germany

    Peter Elsner

  5. Department of Dermatology, University of California, San Francisco, CA, USA

    Howard I. Maibach

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Meding, B. (2020). Atopy as a Factor in the Prognosis of Hand Dermatitis. In: John, S., Johansen, J., Rustemeyer, T., Elsner, P., Maibach, H. (eds) Kanerva’s Occupational Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-68617-2_102

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  • DOI: https://doi.org/10.1007/978-3-319-68617-2_102

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-68615-8

  • Online ISBN: 978-3-319-68617-2

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