Abstract
A disturbed epidermal barrier may lead to irritant contact dermatitis.
An enhanced penetration through skin barrier may facilitate sensitization.
Immunological effects induced by pre-irritation and barrier alteration may further lead to the induction of allergic Type IV-contact dermatitis and Type I (immediate-type reaction) reactions or aggravate allergic reactions.
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Rustemeyer, T., Fartasch, M. (2020). Immunology and Barrier Function of the Skin. In: John, S., Johansen, J., Rustemeyer, T., Elsner, P., Maibach, H. (eds) Kanerva’s Occupational Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-68617-2_1
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DOI: https://doi.org/10.1007/978-3-319-68617-2_1
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