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Therapeutic/Theranostic Use of Radionanomedicine

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Radionanomedicine

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

Abstract

Radionanomedicine is a newly emerged field of medicine extending nuclear medicine by means of nanomaterial technology and platforms. Radionanomedicine utilizes versatility of nanoparticles (NP) and avoids inherent toxic effect of NPs. This is mainly due to the fact that NPs are used in trace amounts for targeting. The therapeutic effect of radionanomedicine comes from ionizing radiation of labeled radionuclides. The core concept of radionanomedicine depends on both characteristics of radionuclides and properties of NPs. The characteristics of NPs including multifunctionality, intrinsic properties are exploited to enhance the therapeutic effect of radiolabeled NPs. In addition, various strategies have been developed to deliver sufficient amount of radiolabeled NPs, such as local administration and co-application of thermal stimuli. In an attempt to improve the therapeutic effect of radionuclides, several approaches have been investigated, such as utilizing intrinsic radioactive properties of NPs or labeling with alpha emitters. The emergence of radionanomedicine is expected to restore of the essence of nuclear medicine as well as to enhance the clinical applicability of nanomedicine.

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Author information

Authors and Affiliations

  1. Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea

    So Won Oh & Dong Soo Lee

  2. Department of Nuclear Medicine, Seoul National University Boramae Medical Center, Seoul, 07061, Republic of Korea

    So Won Oh

  3. Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 03080, Republic of Korea

    Dong Soo Lee

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  1. So Won Oh
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Correspondence to So Won Oh .

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Editors and Affiliations

  1. Department of Nuclear Medicine, Seoul National University, Seoul, Korea (Republic of)

    Dong Soo Lee

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Oh, S.W., Lee, D.S. (2018). Therapeutic/Theranostic Use of Radionanomedicine. In: Lee, D. (eds) Radionanomedicine. Biological and Medical Physics, Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-67720-0_23

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