Skip to main content
SpringerLink
Log in

Room Air Readings of Brain Tissue Oxygenation Probes

  • Conference paper
  • First Online:
Intracranial Pressure & Neuromonitoring XVI

Part of the book series: Acta Neurochirurgica Supplement ((NEUROCHIRURGICA,volume 126))

Abstract

Objective: Brain tissue oxygenation (pbtO2) monitoring with microprobes is increasingly used as an important parameter in addition to intracranial pressure in acutely brain-injured patients. Data on accuracy and long-term drift after use are scarce. We investigated room air readings of used pbtO2 probes for their relationship with the duration of monitoring, geographic location of the center, and manufacturer type.

Methods: After finishing clinically indicated monitoring in patients, pbtO2 probes used in two centers in Berlin and Munich were explanted and cleaned to avoid blood contamination. Immediately afterward, room air readings of partial oxygen pressure (pairO2) from 44 Licox® and 10 Raumedic® pbtO2 probes were recorded. Assumed height above sea level was 42 m for Berlin and 485 m for Munich; this resulted in assumed theoretical pairO2 readings of 157.8 mmHg in Berlin and 149.9 mmHg in Munich.

Results: Licox® probes in Berlin showed a mean pairO2 of 160.5 (SD 14.4) mmHg and of 147.8 (11.9) mmHg in Munich. Raumedic® probes in Berlin showed a mean pairO2 of 170.5 (12.2) mmHg and the single Raumedic® probe used in Munich 155 mmHg. No significant drift was found over time for probes with up to 14 days of monitoring. Prolonged use of up to 20 days showed a clinically negligible drift of 1.2 mmHg per day of use for Licox® probes.

Mean absolute deviation for pairO2 from expected values was 6.4% for Licox® and 9.7% for Raumedic® probes.

Conclusion: Room air partial oxygen pressure pairO2 may be utilized to assess the proper function of a pbtO2 probe. It provides a tool for quality control which is easy to implement. Probe readings are stable in the clinically relevant range, even after prolonged use.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References

  1. Bratton SL, Chestnut RM, Ghajar J, et al. Guidelines for the management of severe traumatic brain injury. X. Brain oxygen monitoring and thresholds. J Neurotrauma. 2007;24(Suppl 1):S65–70.

    PubMed  Google Scholar 

  2. Diringer MN, Bleck TP, Claude Hemphill J 3rd, et al. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical care society’s multidisciplinary consensus conference. Neurocrit Care. 2011;15:211–40.

    Article  PubMed  Google Scholar 

  3. Ngwenya LB, Burke JF, Manley GT. Brain tissue oxygen monitoring and the intersection of brain and lung: a comprehensive review. Respir Care. 2016;61:1232–44.

    Article  PubMed  Google Scholar 

  4. Purins K, Enblad P, Sandhagen B, Lewén A. Brain tissue oxygen monitoring: a study of in vitro accuracy and stability of Neurovent-PTO and Licox sensors. Acta Neurochir. 2010;152:681–8.

    Article  PubMed  Google Scholar 

  5. Stewart C, Haitsma I, Zador Z, Hemphill JC, Morabito D, Manley G, Rosenthal G. The new Licox combined brain tissue oxygen and brain temperature monitor: assessment of in vitro accuracy and clinical experience in severe traumatic brain injury. Neurosurgery. 2008;63:1159–1164; discussion 1164–1165.

    Article  PubMed  Google Scholar 

  6. Atmospheric pressure. Wikipedia. https://en.wikipedia.org/wiki/Atmospheric_pressure. Accessed 15 November 2016.

  7. Ponce LL, Pillai S, Cruz J, Li X, Julia H, Gopinath S, Robertson CS. Position of probe determines prognostic information of brain tissue PO2 in severe traumatic brain injury. Neurosurgery. 2012;70:1492–1502; discussion 1502–1503.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Hawryluk GWJ, Phan N, Ferguson AR, Morabito D, Derugin N, Stewart CL, Knudson MM, Manley G, Rosenthal G. Brain tissue oxygen tension and its response to physiological manipulations: influence of distance from injury site in a swine model of traumatic brain injury. J Neurosurg. 2016;125:1217–28.

    Article  PubMed  Google Scholar 

Download references

Conflicts of interest statement

We declare that we have no conflicts of interest.

Author information

Authors and Affiliations

  1. Department of Neurosurgery, Charité Campus Virchow, Berlin, Berlin, Germany

    Stefan Wolf

  2. Department of Neurosurgery, Klinikum Bogenhausen, Technical University Munich, Munich, Germany

    Ludwig Schürer

  3. Department of Neurosurgery, Eberhard-Karls-University, Tübingen, Germany

    Doortje C. Engel

Authors
  1. Stefan Wolf
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ludwig Schürer
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Doortje C. Engel
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Stefan Wolf .

Editor information

Editors and Affiliations

  1. Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

    Thomas Heldt

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Wolf, S., Schürer, L., Engel, D.C. (2018). Room Air Readings of Brain Tissue Oxygenation Probes. In: Heldt, T. (eds) Intracranial Pressure & Neuromonitoring XVI. Acta Neurochirurgica Supplement, vol 126. Springer, Cham. https://doi.org/10.1007/978-3-319-65798-1_40

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-65798-1_40

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-65797-4

  • Online ISBN: 978-3-319-65798-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation