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Adrenal Gland Injuries

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Diagnostic Imaging in Polytrauma Patients

Abstract

The adrenal gland injuries after major blunt (81.4%) or penetrating (18.6%) trauma are rarely reported especially as isolated lesions and their involvement is more frequent in patient with severe trauma, in association with other lesions. They have been associated with overall increased patient’s morbidity and mortality. In the Injury Severity Score (ISS) stratified analysis, the frequency of adrenal hematoma is increased with higher ISS categories.

Male sex is more affected than the female with a ratio of 76.4% men and 23.6% women. The predominance of male than female is particularly evident in the case of young male patients with penetrating wounds.

Most of the lesions are unilateral and right sided.

There are not specific clinical signs of adrenal lesion in polytrauma patients; only rarely, in the case of serious bilateral adrenal gland involvement, they may have an acute adrenal insufficiency syndrome that, if not ready-treated, causes a risk for the life of the patient.

Because of the rarity of this trauma nowadays there isn’t a consensus or algorithm for the treatment. The mortality rates of patients range from 7 to 32%.

Since the Computed Tomography (CT) is routinely used for the evaluation of polytraumatic patient, the diagnosis of adrenal trauma has become more frequent; before of using of CT the diagnosis was often random during surgery or postmortem autopsy.

The confidence with typical CT findings of adrenal trauma is fundamental for the radiologist to avoid misdiagnosis.

The management of adrenal trauma depends on many factors, including the presence and the severity of other injuries; therefore, it can be either surgical or nonsurgical.

The follow-up of the adrenal lesion can be performed both with CT and Magnetic Resonance Imaging (MRI), in same cases Ultrasound (US) has a role too.

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References

  1. Elsayes KM, Mukundan G, Narra VR, et al. Adrenal masses: MR imaging features with pathologic correlation. Radiographics. 2004;24(Suppl 1):S73–86.

    Article  PubMed  Google Scholar 

  2. Sinelnikov AO, Abujudeh HH, Chan D, et al. CT manifestations of adrenal trauma: experience with 73 cases. Emerg Radiol. 2007;13:313–8.

    Article  PubMed  Google Scholar 

  3. To’o KJ, Duddalwar VA. Imaging of traumatic adrenal injury. Emerg Radiol. 2012;19:499–503. doi:10.1007/s10140-012-1063-y.

    Article  PubMed  Google Scholar 

  4. Stawicki SP, Hoey BA, Grossman MD. Adrenal gland trauma is associated with high injury severity and mortality. Curr Surg. 2003;60:431–6.

    Article  PubMed  Google Scholar 

  5. Burks DW, Mirvis SE, Shanmuganathan K. Acute adrenal injury after blunt abdominal trauma: CT findings. AJR Am J Roentgenol. 1992;158:503–7.

    Article  CAS  PubMed  Google Scholar 

  6. Pinto A, Scaglione M, Guidi G, et al. Role of multidetector row computed tomography in the assessment of adrenal gland injuries. Eur J Radiol. 2006;59:355–8.

    Article  PubMed  Google Scholar 

  7. Kahraman AS, Kahraman B, Ozdemir ZM et al (2016) Traumatic adrenal hematoma: clinical and imaging findings. ECR 2016. Type: Scientific Exhibit, Poster No: C-0193. doi:10.1594/ecr2016/C-0193.

  8. Lee MJ, Kim AG, Jang JE, et al. A case of traumatic bilateral adrenal hemorrhage mimicking bilateral adrenal adenomas. Yeungnam Univ J Med. 2012;29:35–7. doi:10.1270/yujm.2012.29.1.35.

    Article  Google Scholar 

  9. Mahajan A, Rao V, Thakur M et al (2010) Adrenal injury after blunt abdominal trauma: correlation between CT findings and injury severity score ECR 2010, Poster No.: C-1176. Doi:10.1594/ecr2010/C-1176.

  10. Cardia G, Loverre G, Pomarico N, et al. Traumatic retroperitoneal lesions. Ann Ital Chir. 2000;71:457–67.

    CAS  PubMed  Google Scholar 

  11. Gabalshehab L, Alagiri M. Traumatic adrenal injuries. J Urol. 2005;173:1330–1.

    Article  Google Scholar 

  12. Mehrazin R, Derweesh IH, Kincade MC, et al. Adrenal trauma: Elvis Presley Memorial Trauma Center experience. Urology. 2007;70:851–5.

    Article  PubMed  Google Scholar 

  13. Panda A, Kumar A, Gamanagatti S, et al. Are traumatic bilateral adrenal injuries associated with higher morbidity and mortality? A prospective observational study. J Trauma Manag Outcomes. 2015;9:6. doi:10.1186/s13032-015-0026-1.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Sivit CJ, Ingram JD, Taylor GA, et al. Posttraumatic adrenal hemorrhage in children: CT findings in 34 patients. AJR Am J Roentgenol. 1992;58:1299–302.

    Article  Google Scholar 

  15. Gomez RG, McAninch JW, Carrol PR. Adrenal gland trauma: diagnosis and management. J Trauma. 1993;35:870–4.

    Article  CAS  PubMed  Google Scholar 

  16. Roupakias S, Papoutsakis M, Tsikopoulos G. Adrenal injuries following blunt abdominal trauma in children: report of two cases. Ulus Travma Acil Cerrahi Derg. 2012;18:171–4.

    Article  PubMed  Google Scholar 

  17. Woodruff S, Yeung M, Grodski S, et al. Adrenal injuries and incidentalomas in trauma patients at an urban trauma centre. J Curr Surg. 2012;2:123–9.

    Google Scholar 

  18. deRoux SJ, Prendergast NC. Adrenal lacerations in child abuse: a marker of severe trauma. Pediatr Surg Int. 2000;16:121–3.

    Article  CAS  PubMed  Google Scholar 

  19. Iuchtman M, Breitgand A. Traumatic adrenal hemorrhage in children: an indicator of visceral injury. Pediatr Surg Int. 2000;16:586–8.

    Article  CAS  PubMed  Google Scholar 

  20. Shehab LG, Alagiri M. Traumatic adrenal injuries. J Urol. 2005;173:1330–1.

    Article  Google Scholar 

  21. Kim DG, Jung HS, et al. Endovascular treatment of a post-traumatic adrenal hemorrhage in a pediatric patient: a case report. J Korean Soc Radiol. 2016;75:508–11.

    Article  Google Scholar 

  22. Nimkin K, Teeger S, Wallach MT, et al. Adrenal hemorrhage in abused children: imaging and postmortem findings. AJR Am J Roentgenol. 1994;162:661–3.

    Article  CAS  PubMed  Google Scholar 

  23. Sayit AT, Sayit E, Gunbey HP, et al. Imaging of unilateral adrenal hemorrhages in patients after blunt abdominal trauma: report of two cases. Chin J Traumatol. 2017;20:52–5. doi:10.1016/j.cjtee.2016.05.002.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Liao CH, Lin J, Fu CY, et al. Adrenal gland trauma: is extravasation an absolute indication for intervention? World J Surg. 2015;39:1312–9. doi:10.1007/s00268-015-2953-4.

    Article  PubMed  Google Scholar 

  25. Scaglione M. Emergency radiology: state of the art. Radiol Med. 2015;120:1–2. doi:10.1007/s11547-014-0481-1.

    Article  PubMed  Google Scholar 

  26. Sivit CJ, Taylor GA, Bulas DI, et al. Blunt trauma in children: significance of peritoneal fluid. Radiology. 1991;178:185–8.

    Article  CAS  PubMed  Google Scholar 

  27. Miele V, Piccolo CL, Sessa B, et al. Comparison between MRI and CEUS in the follow-up of patients with blunt abdominal trauma managed conservatively. Radiol Med. 2016;121:27–37. doi:10.1007/s11547-015-0578-1.

    Article  PubMed  Google Scholar 

  28. Sessa B, Trinci M, Ianniello S, et al. Blunt abdominal trauma: role of contrast-enhanced ultrasound in the detection and staging of abdominal traumatic lesions compared with US and CE-MDCT. Radiol Med. 2015;120:180–9. doi:10.1007/s11547-014-0425-9.

    Article  PubMed  Google Scholar 

  29. Pinto F, Valentino M, Romanini L, et al. The role of CEUS in the assessment of haemodinamically stable patients with blunt abdominal trauma. Radiol Med. 2015;120:3–11. doi:10.1007/s11547-014-0455-3.

    Article  PubMed  Google Scholar 

  30. Miele V, Di Giampietro I, Ianniello S, et al. Diagnostic imaging in pediatric polytrauma management. Radiol Med. 2015;120:33–49. doi:10.1007/s11547-014-0469-x.

    Article  PubMed  Google Scholar 

  31. Menichini G, Sessa B, Trinci M, et al. Accuracy of contrast-enhanced ultrasound (CEUS) in the identification and characterization of traumatic solid organ lesions in children: a retrospective comparison with baseline-US and CE-MDCT. Radiol Med. 2015;120:989–1001. doi:10.1007/s11547-015-0535-z.

    Article  PubMed  Google Scholar 

  32. Miele V, Piccolo CL, Trinci M, et al. Diagnostic imaging of blunt abdominal trauma in pediatric patients. Radiol Med. 2016;121:409–30. doi:10.1007/s11547-016-0637-2.

    Article  PubMed  Google Scholar 

  33. Di Giacomo V, Trinci M, Van der Byl G, et al. Ultrasound in newborns and children suffering from nontraumatic acute abdominal pain: imaging with clinical and surgical correlation. J Ultrasound. 2015;18:385–93. doi:10.1007/s40477-014-0087-4.

    Article  PubMed  Google Scholar 

  34. Trinci M, Trinci CM, Galluzzo M, et al. Neonatal adrenal hemorrhage. In: Miele V, Trinci M, editors. Imaging non-traumatic abdominal emergencies in pediatric patients. Switzerland: Springer International Publishing; 2016. p. 181–92.

    Chapter  Google Scholar 

  35. Jordan E, Poder L, Courtier J, et al. Imaging of nontraumatic adrenal hemorrhage. AJR Am J Roentgenol. 2012;199:W91–8. doi:10.2214/AJR.11.7973.

    Article  PubMed  Google Scholar 

  36. Wedmid A, Palese M. Diagnosis and treatment of the adrenal cyst. Curr Urol Rep. 2010;11:44–50. doi:10.1007/s11934-009-008-1.

    Article  PubMed  Google Scholar 

  37. Cagini L, Gravante S, Malaspina CM, et al. Contrast enhanced ultrasound (CEUS) in blunt abdominal trauma. Crit Ultrasound J. 2013;15:5. doi:10.1186/2036-7902-5-S1-S9.

    Article  Google Scholar 

  38. Valentino M, Serra C, Pavlica P, et al. Contrast-enhanced ultrasound for blunt abdominal trauma. Semin Ultrasound CT MR. 2007;28:130–40.

    Article  PubMed  Google Scholar 

  39. Miele V, Piccolo CL, Galluzzo M, et al. Contrast enhanced ultrasound (CEUS) in blunt abdominal trauma. Br J Radiol. 2016;89(1061):20150823. doi:10.1259/bjr.20150823.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Cosgrove D. Ultrasound contrast agent: an overview. Eur J Radiol. 2006;60:324–30.

    Article  PubMed  Google Scholar 

  41. Pinto F, Miele V, Scaglione M, et al. The use of contrast-enhanced ultrasound in blunt abdominal trauma: advantages and limitations. Acta Radiol. 2014;55:776–84. doi:10.1177/0284185113505517. Epub 2013 Sep 23

    Article  PubMed  Google Scholar 

  42. Marti JL, Millet J, Sosa JA, et al. Spontaneous adrenal hemorrhage with associated masses: etiology and management in 6 cases and a review of 133 reported cases. World J Surg. 2012;36:75–82. doi:10.1007/s00268-011-1338-6.

    Article  PubMed  Google Scholar 

  43. Rhea JT, Garza DH, Novelline RA. Controversies in emergency radiology CT versus ultrasound in the evaluation of blunt abdominal trauma. Emerg Radiol. 2004;10:289–95.

    PubMed  Google Scholar 

  44. Pinto A, Scaglione M, Pinto F, et al. Adrenal injuries: spectrum of CT findings. Emerg Radiol. 2003;10:30–3.

    PubMed  Google Scholar 

  45. Scialpi M, Palumbo B, Pierotti L, et al. Detection and characterization of focal liver lesions by split-bolus multidetector-row CT: diagnostic accuracy and radiation dose in oncologic patients. Anticancer Res. 2014;34:4335–44.

    PubMed  Google Scholar 

  46. Lee YS, Jeong JJ, Nam KH, et al. Adrenal injury following blunt abdominal trauma. World J Surg. 2010;34:1971–4. doi:10.1007/s00268-010-0537-x.

    Article  PubMed  Google Scholar 

  47. Daly KP, Ho CP, Persson DL, Gay SB. Traumatic retroperitoneal injuries: review of multidetector CT findings. Radiographics. 2008;28:1571–90. doi:10.1148/rg.286075141.

    Article  PubMed  Google Scholar 

  48. Sacerdote MG, Johnson PT, Fishman EK. CT of the adrenal gland: the many faces of adrenal hemorrhage. Emerg Radiol. 2012;19:53–60. doi:10.1007/s10140-011-0989-9.

    Article  PubMed  Google Scholar 

  49. Ikeda O, Urata J, Araki Y, et al. Acute adrenal hemorrhage after blunt trauma. Abdom Imaging. 2007;32:248–52.

    Article  CAS  PubMed  Google Scholar 

  50. Dunnick NR, Korobkin M. Imaging of adrenal Incidentalomas: current status. AJR Am J Roentgenol. 2002;179:559–68.

    Article  PubMed  Google Scholar 

  51. Pinto A, Brunese L, Pinto F, et al. The concept of error and malpractice in radiology. Semin Ultrasound CT MR. 2012;33:275–9. doi:10.1053/j.sult.2012.01.009.

    Article  PubMed  Google Scholar 

  52. Elsayes KM, Mukundan G, Narra VR, et al. Adrenal masses: MR imaging features with pathologic correlation. Radiographics. 2004;1:S73–86.

    Article  Google Scholar 

  53. Schultz CL, Haaga JR, Fletcher BD, et al. Magnetic resonance imaging of the adrenal glands: a comparison with computer tomography. AJR Am J Roentgenol. 1984;143:1235–40.

    Article  CAS  PubMed  Google Scholar 

  54. Rammelt S, Mucha D, Amlang M, et al. Bilateral adrenal hemorrhage in blunt abdominal trauma. J Trauma. 2000;48:332–5.

    Article  CAS  PubMed  Google Scholar 

  55. Igwilo OC, Sulkowski RJ, Shah MR, et al. Embolization of traumatic adrenal hemorrhage. J Trauma. 1999;47:1153–5.

    Article  CAS  PubMed  Google Scholar 

  56. Roupakias S, Papoutsakis M, Mitsakou P. Blunt adrenal gland trauma in the pediatric population. Asian J Surg. 2011;34:10310. doi:10.1016/j.asjsur.2011.08.003.

    Article  Google Scholar 

  57. Udobi KF, Childs EW. Adrenal crisis after traumatic bilateral adrenal hemorrhage. J Trauma. 2001;51:597–600.

    CAS  PubMed  Google Scholar 

  58. Ikekpeazzu N, Bonadies JA, Sreenivas VI. Acute bilateral adrenal hemorrhage secondary to rough truck ride. J Emerg Med. 1996;14:15–8.

    Article  CAS  PubMed  Google Scholar 

  59. Castaldo ET, Guillamondegui OD, Greco JA, et al. Are adrenal injuries predictive of adrenal insufficiency in patients sustaining blunt trauma? Am Surg. 2008;74:262–6.

    PubMed  Google Scholar 

  60. Francque SM, Schwagten VM, Ysebaert DK, et al. Bilateral adrenal haemorrhage and acute adrenal insufficiency in a blunt abdominal trauma: a case-report and literature review. J Emerg Med. 2004;11:164–7.

    Google Scholar 

  61. Baccot S, Tiffet O, Bonnot P, et al. Bilateral post-traumatic adrenal hemorrhage. Report of a case with acute adrenal insufficiency. Ann Chir. 2000;125:273–5.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Margherita Trinci M.D. .

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Trinci, M. et al. (2018). Adrenal Gland Injuries. In: Miele, V., Trinci, M. (eds) Diagnostic Imaging in Polytrauma Patients. Springer, Cham. https://doi.org/10.1007/978-3-319-62054-1_18

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