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Rare Papillary Thyroid Carcinomas

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Rare Tumors of the Thyroid Gland

Abstract

Papillary thyroid carcinoma (PTC) is a malignant epithelial tumour showing evidence of follicular cell differentiation and a set of distinctive nuclear features. Following the criteria of the last WHO classification, either papillae or invasion is required for a diagnosis of PTC [1]. Although the diagnosis of PTC is not usually problematic, numerous variants of PTC have been recognized, sometimes raising diagnostic difficulties. In the follicular-patterned tumours with PTC nuclear features, the diagnosis is based primarily on the identification of invasion signs and will not be addressed in this book [1, 2]. It is particularly important to recognize those variants of PTC that are associated with clinical aggressiveness, as is the case with tall cell variant, columnar cell variant, the recently described hobnail (micropapillary) variant of PTC and PTC displaying diffuse nuclear immunoreactivity for P53. Since the hobnail (micropapillary) variant of PTC is the rarest form of the aforementioned three morphologic variants and its diagnosis is more difficult, it will be specially addressed in this chapter, together with other (very) unusual forms of PTC.

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Author information

Authors and Affiliations

  1. Department of Pathology, Clinical University Hospital, Galician Healthcare Service (SERGAS), Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain

    José M. Cameselle-Teijeiro

  2. Medical Faculty, University of Santiago de Compostela, Santiago de Compostela, Spain

    José M. Cameselle-Teijeiro

  3. Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal

    Catarina Eloy, Isabel Amendoeira, Paula Soares, Miguel Melo & Manuel Sobrinho-Simões

  4. Department of Pathology, Medical Faculty, University of Porto, Porto, Portugal

    Catarina Eloy, Paula Soares & Manuel Sobrinho-Simões

  5. i3S - Instituto de Investigação e Inovação em Saúde, Porto, Portugal

    Catarina Eloy, Paula Soares, Miguel Melo & Manuel Sobrinho-Simões

  6. Department of Pathology, Hospital S. João, Porto, Portugal

    Isabel Amendoeira & Manuel Sobrinho-Simões

  7. Department of Pathology, Hospital Lucus Augusti, Galician Healthcare Service (SERGAS), Lugo, Spain

    Javier Caneiro-Gómez

  8. Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal

    Miguel Melo

  9. Unit of Endocrinology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal

    Miguel Melo

Authors
  1. José M. Cameselle-Teijeiro
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  2. Catarina Eloy
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  3. Isabel Amendoeira
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  4. Paula Soares
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  5. Javier Caneiro-Gómez
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  6. Miguel Melo
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  7. Manuel Sobrinho-Simões
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Corresponding author

Correspondence to José M. Cameselle-Teijeiro .

Editor information

Editors and Affiliations

  1. Dpt. of Anatomic Pathology, Clinical University Hospital (SERGAS), Medical Faculty, University of Santiagode Compostela, Santiago de Compostela, Spain

    José Manuel Cameselle-Teijeiro

  2. Medical Faculty, University of Porto, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), i3S – Instituto deInvestigação e Inovação em Saúde, Porto, Portugal

    Catarina Eloy

  3. Department of Pathology, Medical Faculty, University of Porto, Department of Pathology Hospital S. João, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), i3S - Instituto de Investigação e Inovação em Saúde, Porto, Portugal

    Manuel Sobrinho-Simões

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Cameselle-Teijeiro, J.M. et al. (2018). Rare Papillary Thyroid Carcinomas. In: Cameselle-Teijeiro, J., Eloy, C., Sobrinho-Simões, M. (eds) Rare Tumors of the Thyroid Gland. Springer, Cham. https://doi.org/10.1007/978-3-319-61182-2_2

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  • DOI: https://doi.org/10.1007/978-3-319-61182-2_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-61181-5

  • Online ISBN: 978-3-319-61182-2

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