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Animal Models of Stress and Tinnitus

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Tinnitus and Stress

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Abstract

Here I briefly review the major stress system of the body, an intrinsic stress system in the cochlea, how stress can be recognized in laboratory animals, and how stress can be induced in animals. Then I discuss the effects of stress on the cochlea and the auditory central nervous system. This leads to the examination of animal models of stress that is causal to or exacerbates tinnitus and briefly also how tinnitus may cause stress. I end with a discussion of behavioral tests that are used to decide whether animals have tinnitus. I also suggest that these various test procedures may cause or exaggerate signs of tinnitus.

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Acknowledgments

This work was supported by the Natural Science and Engineering Research Council (NSERC) of Canada.

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Authors and Affiliations

  1. Department of Physiology, Pharmacology, and Psychology, University of Calgary, Calgary, AB, Canada

    Jos J. Eggermont Ph.D., F.R.S.C.

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  1. Jos J. Eggermont Ph.D., F.R.S.C.
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Correspondence to Jos J. Eggermont Ph.D., F.R.S.C. .

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Editors and Affiliations

  1. Charité Universitätsmedizin , Berlin, Germany

    Agnieszka Szczepek

  2. Charité Universitätsmedizin , Berlin, Germany

    Birgit Mazurek

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Eggermont, J.J. (2017). Animal Models of Stress and Tinnitus. In: Szczepek, A., Mazurek, B. (eds) Tinnitus and Stress. Springer, Cham. https://doi.org/10.1007/978-3-319-58397-6_5

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  • DOI: https://doi.org/10.1007/978-3-319-58397-6_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-58396-9

  • Online ISBN: 978-3-319-58397-6

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