Abstract
Etizolam is an agonist at the GABA-A receptor and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative, and skeletal muscle relaxant properties. The compound binds at the benzodiazepine binding site of the GABA-benzodiazepine receptor complex. Etizolam is licensed only in a few countries for the treatment of anxiety, panic, and insomnia. Also, there are only few clinical studies investigating clinically effects in the indications mentioned above. Regarding side effects, the risk of tolerance and dependency is comparable to other benzodiazepines. However, regarding the illicit non-prescribed use of etizolam, there are several reports on withdrawal, craving, and other related symptoms.
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Zwanzger, P. (2022). Tranquilizer/Anxiolytics: Benzodiazepines (Short-Acting) – Etizolam. In: Riederer, P., Laux, G., Nagatsu, T., Le, W., Riederer, C. (eds) NeuroPsychopharmacotherapy. Springer, Cham. https://doi.org/10.1007/978-3-319-56015-1_408-1
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DOI: https://doi.org/10.1007/978-3-319-56015-1_408-1
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