Abstract
Immunobullous dermatoses are a group of blistering conditions overlapping in their clinical features. They are divided into two main groups including intraepidermal immunobullous diseases and subepidermal immunobullous disease. In this chapter, the most important immunobullous dermatoses are explained in detail.
References
Amagai M, Tanikawa A, Shimizu T, Hashimoto T, Ikeda S, Kurosawa M, Niizeki H, Aoyama Y, Iwatsuki K, Kitajima Y (2014) Committee for Guidelines for the Management of Pemphigus Disease. Japanese guidelines for the management of pemphigus. J Dermatol 41(6):471–486
Amerian ML, Ahmed AR (1985) Pemphigus erythematosus. Senear-Usher syndrome. Int J Dermatol 24(1):16–25
Carey B, Setterfield J (2019) Mucous membrane pemphigoid and oral blistering diseases. Clin Exp Dermatol 44(7):732–739
Chorzelski T, Hashimoto T, Maciejewska B, Amagai M, Anhalt GJ, Jablonska S (1999) Paraneoplastic pemphigus associated with Castleman tumor, myasthenia gravis and bronchiolitis obliterans. J Am Acad Dermatol 41(3 Pt 1):393–400
Cobos G, Mub E, Cohen J, Beasley J, Brinster N, Femia A (2017) Epidermolysis bullosa acquisita. Dermatol Online J 23(12):13030/qt4jk4333w
Cohen S, Strowd LC, Pichardo RO (2018) Pemphigoid gestationis: a case series and review of the literature. J Dermatolog Treat 29(8):815–818
Díaz MS, Morita L, Ferrari B, Sartori S, Greco MF, Sobrevias Bonells L, González-Enseñat MA, Vicente Villa MA, Larralde M (2019) Linear IgA bullous dermatosis: a series of 17 cases. Actas Dermosifiliogr 110(8):673–680
Fong M, Gandhi GR, Gharbi A, Hafsi W (2021) Pemphigoid gestationis. [Updated 2021 Jan 15]. In: StatPearls [Internet]. StatPearls Publishing, Treasure Island. https://www.ncbi.nlm.nih.gov/books/NBK470287/
Hashimoto T (2001a) Immunopathology of paraneoplastic pemphigus. Clin Dermatol 19(6):675–682
Hashimoto T (2001b) Immunopathology of IgA pemphigus. Clin Dermatol 19(6):683–689
Hashimoto T (2003) Recent advances in the study of the pathophysiology of pemphigus. Arch Dermatol Res 295(Suppl 1):S2–S11
Hashimoto T (2008) Treatment strategies for pemphigus vulgaris in Japan. Expert Opin Pharmacother 9(9):1519–1530
Hashimoto T, Nishikawa T (2015) Nomenclature for diseases with IgA anti-keratinocyte cell surface autoantibodies. Br J Dermatol 173(3):868–869
Hashimoto T, Kiyokawa C, Mori O, Miyasato M, Chidgey MA, Garrod DR, Kobayashi Y, Komori K, Ishii K, Amagai M, Nishikawa T (1997) Human desmocollin 1 (Dsc1) is an autoantigen for the subcorneal pustular dermatosis type of IgA pemphigus. J Invest Dermatol 109(2):127–131
Hashimoto T, Tsuruta D, Koga H, Fukuda S, Ohyama B, Komai A, Karashima T, Ohata C, Teye K, Ishii N (2016) Summary of results of serological tests and diagnoses for 4774 cases of various autoimmune bullous diseases consulted to Kurume University. Br J Dermatol 175(5):953–965
Hashimoto T, Teye K, Ishii N (2017) Clinical and immunological studies of 49 cases of various types of intercellular IgA dermatosis and 13 cases of classical subcorneal pustular dermatosis examined at Kurume University. Br J Dermatol 176(1):168–175
Ishii K, Amagai M, Komai A, Ebihara T, Chorzelski TP, Jablonska S, Ohya K, Nishikawa T, Hashimoto T (1999) Desmoglein 1 and desmoglein 3 are the target autoantigens in herpetiform pemphigus. Arch Dermatol 135(8):943–947
Ishii N, Teye K, Fukuda S, Uehara R, Hachiya T, Koga H, Tsuchisaka A, Numata S, Ohyama B, Tateishi C, Tsuruta D, Furumura M, Hattori S, Kawakami T, Ohata C, Hashimoto T (2015) Anti-desmocollin autoantibodies in non-classical pemphigus. Br J Dermatol 173(1):59–68
Mendes FB, Hissa-Elian A, Abreu MA, Gonçalves VS (2013) Review: dermatitis herpetiformis. An Bras Dermatol 88(4):594–599
Miyamoto D, Santi CG, Aoki V, Maruta CW (2019) Bullous pemphigoid. An Bras Dermatol 94(2):133–146
Murrell DF, Dick S, Ahmed AR, Amagai M, Barnadas MA, Borradori L, Bystryn JC, Cianchini G, Diaz L, Fivenson D, Hall R, Harman KE, Hashimoto T, Hertl M, Hunzelmann N, Iranzo P, Joly P, Jonkman MF, Kitajima Y, Korman NJ, Martin LK, Mimouni D, Pandya AG, Payne AS, Rubenstein D, Shimizu H, Sinha AA, Sirois D, Zillikens D, Werth VP (2008) Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus. J Am Acad Dermatol 58(6):1043–1046
Mutasim DF, Bilic M, Hawayek LH, Pipitone MA, Sluzevich JC (2005) Immunobullous diseases. J Am Acad Dermatol 52(6):1029–1043
Numata S, Teye K, Tsuruta D, Sogame R, Ishii N, Koga H, Natsuaki Y, Tsuchisaka A, Hamada T, Karashima T, Nakama T, Furumura M, Ohata C, Kawakami T, Schepens I, Borradori L, Hashimoto T (2013) Anti-α-2-macroglobulin-like-1 autoantibodies are detected frequently and may be pathogenic in paraneoplastic pemphigus. J Invest Dermatol 133(7):1785–1793
Odonwodo A, Vashisht P (2021) Bullous systemic lupus erythematosus. [Updated 2020 May 17]. In: StatPearls [Internet]. StatPearls Publishing, Treasure Island. https://www.ncbi.nlm.nih.gov/books/NBK557445/
On HR, Hashimoto T, Kim SC (2015) Pemphigus herpetiformis with IgG autoantibodies to desmoglein 1 and desmocollin 1. Br J Dermatol 172(4):1144–1146
Robinson ND, Hashimoto T, Amagai M, Chan LS (1999) The new pemphigus variants. J Am Acad Dermatol 40(5 Pt 1):649–671
Salmi TT (2019) Dermatitis herpetiformis. Clin Exp Dermatol 44(7):728–731
Santi CG, Gripp AC, Roselino AM, Mello DS, Gordilho JO, Marsillac PF, Porro AM (2019) Consensus on the treatment of autoimmune bullous dermatoses: bullous pemphigoid, mucous membrane pemphigoid and epidermolysis bullosa acquisita - Brazilian Society of Dermatology. An Bras Dermatol 94(2 Suppl 1):33–47
Saruta H, Ishii N, Teye K, Ono F, Ohyama B, Koga H, Ohata C, Furumura M, Tsuruta D, Hashimoto T (2013) Two cases of pemphigus vegetans with IgG anti-desmocollin 3 antibodies. JAMA Dermatol 149(10):1209–1213
Tateishi C, Tsuruta D, Nakanishi T, Uehara S, Kobayashi H, Ishii M, Hashimoto T (2010) Antidesmocollin-1 antibody-positive, antidesmoglein antibody-negative pemphigus herpetiformis. J Am Acad Dermatol 63(1):e8–e10
Tsuchisaka A, Numata S, Teye K, Natsuaki Y, Kawakami T, Takeda Y, Wang W, Ishikawa K, Goto M, Koga H, Sogame R, Ishii N, Takamori S, Hoshino T, Brandt O, Pas HH, Fujiwara S, Hashimoto T (2016) Epiplakin is a paraneoplastic pemphigus autoantigen and related to bronchiolitis obliterans in Japanese patients. J Invest Dermatol 136(2):399–408
Tsuruta D, Ishii N, Hashimoto T (2012) Diagnosis and treatment of pemphigus. Immunotherapy 4(7):735–745
Yasuda H, Kobayashi H, Hashimoto T, Itoh K, Yamane M, Nakamura J (2000) Subcorneal pustular dermatosis type of IgA pemphigus: demonstration of autoantibodies to desmocollin-1 and clinical review. Br J Dermatol 143(1):144–148
Yoshimura K, Ishii N, Hamada T, Abe T, Ono F, Hashikawa K, Fukuda S, Ohyama B, Koga H, Sogame R, Teye K, Ochiai T, Nakajima H, Nakajima K, Iijima S, Kanzaki M, Kojima K, Nagatani T, Fujimoto W, Karashima T, Nakama T, Ohata C, Furumura M, Tsuruta D, Hashimoto T (2014) Clinical and immunological profiles in 17 Japanese patients with drug-induced pemphigus studied at Kurume University. Br J Dermatol 171(3):544–553
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 Springer Nature Switzerland AG
About this entry
Cite this entry
Hashimoto, T., Tsuruta, D., Tateishi, C., Ishii, N., Bagherani, N. (2022). Immunobullous Dermatoses. In: Smoller, B., Bagherani, N. (eds) Atlas of Dermatology, Dermatopathology and Venereology. Springer, Cham. https://doi.org/10.1007/978-3-319-53808-2_34
Download citation
DOI: https://doi.org/10.1007/978-3-319-53808-2_34
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-53807-5
Online ISBN: 978-3-319-53808-2
eBook Packages: MedicineReference Module Medicine