Skip to main content
SpringerLink
Log in

Small Intestine

  • Chapter
  • First Online:
Clinical Investigations in Gastroenterology

  • 778 Accesses

Abstract

The function of the small bowel can be evaluated by clinical tests of absorption (Chap. 7). Intestinal biopsy, bacteriology, radiology, radio-isotope studies, enteroscopy and serology provide additional information to enable specific diagnoses to be made.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Bibliography

  • Aas K. Studies of hypersensitivity to fish-allergological and serological differentiation between various species of fish. Int Arch Allergy. 1966;30:257.

    Article  CAS  PubMed  Google Scholar 

  • Aas K. The diagnosis of hypersensitivity to ingested foods: reliability of skin prick testing and radioallergosorbent test with different materials. Clin Allergy. 1978;8:39.

    Article  CAS  PubMed  Google Scholar 

  • Aburano T, Yokoyam K, Kinuya S, et al. Indium-111 transferrin imaging for the diagnosis of protein-losing enteropathy. Clin Nucl Med. 1989;14:681–5.

    Article  CAS  PubMed  Google Scholar 

  • Adman SH, Whorwell PJ, Wright R, Phil D. Diagnosis of Crohn’s disease. Dig Dis Sci. 1980;25:911–5.

    Article  Google Scholar 

  • Allun-Jones V, McLaughlan P, Shorthouse M, Workman E, Hunter JO. Food intolerance: a major factor in the pathogenesis of irritable bowel syndrome. Lancet. 1982;2:1115–7.

    Article  Google Scholar 

  • Andre C, Descos L, Landais P, Fermanian J. Assessment of appropriate laboratory measurement to supplement the Crohn’s disease activity index. Gut. 1981;22:571–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Asmark E, Knutsson F, Thoren L. Phaeochromocytoma: diagnostic features. Acta Med Scand. 1967;182:673–80.

    Article  Google Scholar 

  • Attwood SEA, Mealy K, Cafferkey MT, et al. Yersinia infection and acute abdominal pain. Lancet. 1987;1:529–33.

    Article  CAS  PubMed  Google Scholar 

  • Belut D, Moneret-Vautrin DA, Nicholas JP, Grilliat JP. IgE levels in intestinal disease. J Dig Dis Sci. 1980;25:323–32.

    Article  CAS  Google Scholar 

  • Bradborg LL, Rubin CE, Quinton WE. A multipurpose instrument for suction biopsy of the oesophagus, stomach, small bowel and colon. Gastroenterology. 1959;37:1–16.

    Google Scholar 

  • Brignola C, Camperi M, Bazzochi G, Farruggia P, Tragone A, Lan Franch EA. A laboratory index for predicting relapse in asymptomatic patients with Crohn’s disease. Gastroenterology. 1986;91:1490–4.

    Article  CAS  PubMed  Google Scholar 

  • Buscombe J. Radiolabelled human immunoglobulins. Nucl Med Commun. 1995;16:990–1001.

    Article  CAS  PubMed  Google Scholar 

  • Butterworth RJ, WilIiams GT, Hughes LE. Can Crohn’s disease be diagnosed at laparotomy? Gut. 1992;33:140–2.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cacciari E, Salardi S, Volta U, et al. Can antigliadin antibody detect symptomless coeliac disease in children with short stature? Lancet. 1985;1:1469–71.

    Article  CAS  PubMed  Google Scholar 

  • Clarkson EM. A rapid method for the determination of chromium sesquioxide in faecal homogenates. Clin Chim Acta. 1966;16:571–2.

    Google Scholar 

  • Corazza GR, Menozzi MG, Strocchia A, et al. The diagnosis of small bowel bacterial overgrowth. Reliability of jejunal culture and inadequacy of breath hydrogen testing. Gastroenterology. 1990;98:302–9.

    Article  CAS  PubMed  Google Scholar 

  • Crosby WH, Kugler HW. Intraluminal biopsy of the small intestine. Am J Dig Dis. 1975;2:236–41.

    Article  Google Scholar 

  • Crossley JR, Elliott RB. Simple method of diagnosing protein loss enteropathies. BMJ. 1977;1:428–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Curzon G, Walsh J. A method for the determining of urinary indican. Clin Chim Acta. 1962;7:657–63. 1973;3: 191-5.

    Article  CAS  PubMed  Google Scholar 

  • Dawson OJ, Khan AN, Miller V, Ratcliffe JF, Shreeve DR. Detection of inflammatory bowel disease in adults and children: evaluation of a new isotopic technique. BMJ. 1985;291:1227–30.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Evans N, Farrow LJ, Harding A, Stewart IS. New techniques for speeding small intestinal biopsy. Gut. 1970;11:88–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • NICE recommendation Faecal calprotectin diagnostic tests for IBD 2013.

    Google Scholar 

  • Flick AL, Quinton WE, Rubin CE. A personal hydraulic biopsy tube for multiple sampling at any level of the gastrointestinal tract. Gastroenterology. 1961;40:120–6.

    CAS  PubMed  Google Scholar 

  • Florent C, L'Hirondel C, Desmazures C, Aymes C, Bernier JJ. Intestinal clearance of alpha1-antitrypsin: a sensitive method for the detection of protein-losing enteropathy. Gastroenterology. 1981;81:777–80.

    CAS  PubMed  Google Scholar 

  • Ghaffer MH. Labelled leucocyte scintigraphy in inflammatory bowel disease: clinical applications. Gut. 1996;38:1–5.

    Article  Google Scholar 

  • Goka AKJ, Rolston DDK, Mathan VI, Farthing MJG. Diagnosis of giardiasis by specific IgM antibody enzyme-linked immunosorbent assay. Lancet. 1986;2:184–6.

    Article  CAS  PubMed  Google Scholar 

  • Gordts B, Hemelhof W, Retore P, Rahman M, Cadranel S, Butzler JP. Routine culture of Giardia lamblia trophozoites from human duodenal aspirates. Lancet. 1984;2:137.

    Article  CAS  PubMed  Google Scholar 

  • Hamilton I, Wolsey BW, Cobden I, Cooke EM, Shoesmith JG, Axon ATR. Simultaneous culture of saliva and jejunal aspirate in the investigation of small bowel bacterial overgrowth. Gut. 1982;23:847–53.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hanser MF, Alderson PO. Gallium-67 imaging in abdominal disease. Semin Nucl Med. 1982;8:251–70.

    Google Scholar 

  • Harries AD, Fitzsimons E, Fifield R, Dew MJ, Rhodes J. Platelet count; a simple measure of activity in Crohn’s disease. BMJ. 1983;286:1476.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Harvey RF, Bradshaw IM. A simple index of Crohn’s disease activity. Lancet. 1980;i:514.

    Article  Google Scholar 

  • Holdstock G, Ligorria JE, Krawitt EL. Gallium-67 scanning in patients with Crohn’s disease; an aid to the diagnosis of abdominal abscess. Br J Surg. 1982;69:277–8.

    Article  CAS  PubMed  Google Scholar 

  • Holt C, Samuel E. Grey scale ultrasound in Crohn’s disease. Gut. 1979;20:590–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jamum S, Jensen KB. Faecal radioiodine excretion following iv injection of 1311-albumin and 1251-immunoglobulin G in chronic inflammatory bowel disease. Gastroenterology. 1975;68:143–4.

    Google Scholar 

  • Jamum S, Westergaard H, Yssing M, Jensen H. Quantitation of gastrointestinal protein loss by means of 59Fe-labelled iron dextran. Gastroenterology. 1968;55:229–41.

    Google Scholar 

  • Kerlin P, Phillips S. Variability of motility of the ileum and jejunum in healthy humans. Gastroenterology. 1982;92:694–700.

    Google Scholar 

  • Kerr RM, Dubois JJ, Holt PR. Use of the 1251- and 51Cr-labelled albumin for the measurement of gastrointestinal and total albumin catabolism. J Clin Invest. 1967;46:2064–82.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • King CE, Toskes PP. Comparison of the Ig 14C-xylose, 10g lactulose-H2, and 80g glucose-H2 breath tests in patients with small intestine bacterial overgrowth. Gastroenterology. 1986;91:1447–51.

    Article  CAS  PubMed  Google Scholar 

  • King CE, Toskes PP. Small intestinal bacterial overgrowth. Gastroenterology. 1979;76:1035–55.

    CAS  PubMed  Google Scholar 

  • Levitt MD, Hirsch P, Fetzer CA, Sheaman M, Levine AS. Hydrogen excretion after ingestion of complex carbohydrates. Gastroenterology. 1987;92:383–9.

    Article  CAS  PubMed  Google Scholar 

  • Linscheer WG, Abele JE. A new directable small bowel biopsy device. Gastroenterology. 1976;71:575–6.

    CAS  PubMed  Google Scholar 

  • Mackowiak PA. The normal microbial flora. N Engl J Med. 1982;307:83–93.

    Article  CAS  PubMed  Google Scholar 

  • Maki M, Hallstrom O, Verronen P, et al. Reticulin antibody, arthritis and coeliac disease in children. Lancet. 1988;1:479–80.

    Article  CAS  PubMed  Google Scholar 

  • McCrae S, Younger K, Thompson DG, Wingate DL. Sustained mental stress alters human jejunal motor activity. Gut. 1982;23:404–9.

    Article  Google Scholar 

  • Mee AS, Burke M, Vallon AG, Newman J, Cotton PB. Small bowel biopsy for malabsorption: comparison of the diagnostic adequacy of endoscopic forceps and capsule biopsy specimens. BMJ. 1985;291:769–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Miller A, Green M, Robinson D. Simple rule for calculating normal erythrocyte sedimentation rate. BMJ. 1983;286:266.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • O’Farrelly C, Kelly J, Hekkens W, et al. Alpha-gliadin antibodies: a serological test for coeliac disease. BMJ. 1983;286:2007–10.

    Article  PubMed  PubMed Central  Google Scholar 

  • Oias J, Unsworth OJ, Walker-Smith JA. Antigliadin and antireticulin antibodies in screening for coeliac disease. Lancet. 1987;2:157–8.

    Google Scholar 

  • Owen RL, Brandborg LL. Mucosal histopathology of malabsorption. Clin Gastroenterol. 1983;12:575–90.

    CAS  PubMed  Google Scholar 

  • Pearson DJ, Rix KJB, Bentley SJ. Food allergy: how much in the mind? A clinical and psychiatric study of suspected food hypersensitivity. Lancet. 1983;I:1259–61.

    Article  Google Scholar 

  • Peters AM, Osman S, Henderson BL, et al. Clinical experience with 99mTc-hexamethylpropyleneamineoxime for labelling leukocytes and imaging inflammation. Lancet. 1986;25:946–9.

    Article  Google Scholar 

  • Prout BJ. A rapid method of obtaining a jejunal biopsy using a Crosby capsule and gastrointestinal fibrescope. Gut. 1974;I5:571–2.

    Article  Google Scholar 

  • Rachmilewitz D, Saunders DR. An improvement in the ease of passing a hydraulic biopsy tube. Gastroenterology. 1975;49:571–2.

    Google Scholar 

  • Rheingold OJ, Tedesco FJ, Block FE, Maldonado A, Miale Jr A. 67Ga citrate scintiscanning in active inflammatory bowel disease. Dig Dis Sci. 1979;24:363–8.

    Article  CAS  PubMed  Google Scholar 

  • Rubini ME, Sheahy TW. Exudative enteropathy. A comparative study of 51CrCI3 and 1311-PVP. J Lab Clin Med. 1961;58:892–901.

    CAS  PubMed  Google Scholar 

  • Salter RH, Girdwood TG. Peroral jejunal biopsy with Watson capsule and Scott-Harden duodenal intubation tube. Lancet. 1983;2:1460.

    Article  CAS  PubMed  Google Scholar 

  • Savilahti E, Viander M, Perkkio M, Vainio E, Kalimo K, Reunala T. 19A anti- gliadin antibodies: a marker of mucosal damage in childhood coeliac disease. Lancet. 1983;1:320–2.

    Article  CAS  PubMed  Google Scholar 

  • Scaoili E, Cardamone C, Scagliarini M, Zagari RM, Bazzoli F, Belluzzi A. Can faecal calprotectin better stratify Crohn’s Disease Activity Index? Ann Gastroenterol. 2015;28:247–52.

    Google Scholar 

  • Scott BB, Jenkins D. Endoscopic small intestinal biopsy. Gastrointest Endosc. 1981;27:162–7.

    Article  CAS  PubMed  Google Scholar 

  • Sivadasan K, Kurien B, John TJ. Rapid diagnosis of typhoid fever by antigen detection. Lancet. 1984;1:134–5.

    Article  CAS  PubMed  Google Scholar 

  • Stanghellini V, Camilleri M, Malagelada J-R. Chronic idiopathic intestinal pseudo-obstruction (ClIP): clinical and intestinal manometric findings. Gut. 1987;28:5–12.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Staniforth DH, Rose D. Statistical analysis of the lactuloselbreath hydrogen test in the measurement of orocaecal transit: its variability and predictive value in assessing drug action. Gut. 1989;30:171–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Taylor RH, Waterman S. Single intubation test for investigation of malabsorption and diarrhoea. Gut. 1983;24:680–2.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Thompson DG, Binfield P, De Belder A, O’Brien J, Warren S, Wilson M. Extra-intestinal influences on exhaled breath hydrogen measurements during the investigation of gastrointestinal disease. Gut. 1985;26:1349–52.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Thompson DG, Wingate DL, Archer L, Benston MJ, Green WJ, Hardy RJ. Normal patterns of human upper small bowel activity recorded by prolonged radiotelemetry. Gut. 1980;21:500–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Unsworth OJ, Walker-Smith JA, Holborrow EJ. Gliadin and reticulin antibodies in childhood coeliac disease. Lancet. 1983;1:874–5.

    Article  CAS  PubMed  Google Scholar 

  • Van Hees PAM, Van Elteren PH, Van Lier HJJ, Van Tongeren JHM. An index of inflammatory activity in patients with Crohn’s disease. Gut. 1980;21:279–86.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wald A, Van Thiel DH, Hoechstetter L. Gastrointestinal transit the effect of the menstrual cycle. Gastroenterology. 1981;80:994–8.

    Google Scholar 

  • Walsham NA, Sherwood RA. Faecal calprotectin in inflammatory bowel disease. Clin Exp Gastroenterol. 2016;9:21–9.

    PubMed  PubMed Central  Google Scholar 

  • Whorwell PI, Maxton DG, Martin DL. Post-colonoscopic retrograde ileography. Lancet. 1988;1:738–9.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Bishop Auckland, UK

    Malcolm C. Bateson

  2. Edinburgh, Midlothian, UK

    Ian A. D. Bouchier

Authors
  1. Malcolm C. Bateson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ian A. D. Bouchier
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this chapter

Cite this chapter

Bateson, M.C., Bouchier, I.A.D. (2017). Small Intestine. In: Clinical Investigations in Gastroenterology. Springer, Cham. https://doi.org/10.1007/978-3-319-53786-3_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-53786-3_6

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-53785-6

  • Online ISBN: 978-3-319-53786-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation