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Pathological Diagnosis of Inflammatory Bowel Disease

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Inflammatory Bowel Disease

Part of the book series: Clinical Gastroenterology ((CG))

Abstract

Treatment of inflammatory bowel disease (IBD) requires a multidisciplinary approach which relies heavily on pathology to subclassify the disease as ulcerative colitis (UC) or Crohn’s disease (CD), grade inflammatory activity, and assess for the presence of dysplasia. Despite the increasing use of molecular approaches by the modern pathologist, diagnosis and evaluation of IBD is achieved principally through microscopic examination of hematoxylin and eosin (H&E) stained tissue and gross examination of surgically resected specimens. However, as our understanding of IBD increases, there is likely to be an ever-increasing role of genetics in the IBD diagnosis and assessment. In this chapter, pathological diagnosis of IBD and how genetics may play an increasingly important role in IBD diagnosis and treatment are discussed.

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Author information

Authors and Affiliations

  1. Department of Pathology, The University of Chicago, 5841 S. Maryland Ave., MC1089, AMB P313, Chicago, IL, 60637, USA

    Le Shen MD, PhD

  2. Department of Pathology, The University of Chicago, 5841 S. Maryland Ave., MC1089, AMB P310, Chicago, IL, 60637, USA

    Christopher R. Weber MD, PhD

Authors
  1. Le Shen MD, PhD
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  2. Christopher R. Weber MD, PhD
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Corresponding author

Correspondence to Christopher R. Weber MD, PhD .

Editor information

Editors and Affiliations

  1. Inflammatory Bowel Disease Center, The University of Chicago Medicine, Chicago, Illinois, USA

    Russell D. Cohen

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© 2017 Springer International Publishing AG

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Shen, L., Weber, C.R. (2017). Pathological Diagnosis of Inflammatory Bowel Disease. In: Cohen, R. (eds) Inflammatory Bowel Disease. Clinical Gastroenterology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-53763-4_8

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  • DOI: https://doi.org/10.1007/978-3-319-53763-4_8

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  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-53761-0

  • Online ISBN: 978-3-319-53763-4

  • eBook Packages: MedicineMedicine (R0)

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