Abstract
Within the realm of lymphatic disease treatment, there are many therapeutic interventions available, as highlighted in previous chapters. Treatment of lymphedema (LE) is very challenging. Therapeutic options in LE include conservative and operative modalities and should be individualized with regard to the circumstances of the patient and the lymphedema by a multidisciplinary approach. These circumstances include age, comorbidities, prognosis of (malignant) disease, psychosocial aspects, weight, and physical potential. The goals for conservative treatment are to eliminate edema by reducing interstitial fluid accumulation and to stimulate lymphatic propulsion by compression. However, prevention programs of lymphedema after breast cancer treatment are essential. These programs include baseline measurements prior to operation. Sun et al. (Breast Cancer Res Treat 157:229–240, 2016) showed the necessity of overcoming logistical barriers to improve the quality and accuracy of lymphedema screening and consequently early treatment, which reduces the duration and severity of loss of quality of life.
Highlighted References
Disipio T, Rye S, Newman B, Hayes S. Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis. Lancet Oncol. 2013;14(6):500–15.
Huang T-W, Tseng S-H, Lin C-C, Bai C-H, Chen C-S, Hung C-S, et al. Effects of manual lymphatic drainage on breast cancer-related lymphedema: a systematic review and meta-analysis of randomized controlled trials. World J Surg Oncol. 2013;11(1):15.
Dieli-Conwright CM, Orozco BZ. Exercise after breast cancer treatment: current perspectives. Breast Cancer (Dove Med Press). 2015;7:353–62.
Viehoff PB, Potijk F, Damstra RJ, Heerkens YF, van Ravensberg CD, van Berkel DM, et al. Identification of relevant ICF (International classification of functioning, disability and health) categories in lymphedema patients: a cross-sectional study. SONC. 2015;54(8):1218–24.
Devoogdt N, De Groef A, Hendrickx A, DAMSTRA R, Christiaansen A, Geraerts I, et al. Lymphoedema functioning, disability and health questionnaire for lower limb lymphoedema (lymph-ICF-LL): reliability and validity. Phys Ther. 2014;94(5):705–21.
References
Rockson SG, Miller LT, Senie R, Brennan MJ, et al. American Cancer Society lymphedema workshop. Workgroup III: diagnosis and management of lymphedema. Cancer. 1998;83(12 suppl American):2882–5.
Damstra RJ, Kaandorp C. Multidisciplinary guidelines for early diagnosis and management. J Lymphoedema. 2006;1(1):37–65.
International Lymphoedema Framework. Best practice for the management of lymphedema. International consensus. London: MEP Ltd; 2006. p. 1–60.
Shaw C, Mortimer PS, Judd PA. Randomized controlled trial comparing a low-fat diet with a weight-reduction diet in breast cancer-related lymphedema. Cancer. 2007;109(10):1949–56.
Meeske KA, Sullivan-Halley J, Ashley W, et al. Risk factors for arm lymphedema following breast cancer diagnosis in black women and white women. Breast Cancer Res Treat. 2009;113(2):383–91.
Petrek JA, Senie RT, Peters M, Rosen PP. Lymphedema in a cohort of breast carcinoma survivors 20 years after diagnosis. Cancer. 2001;92(6):1368–77.
Pain SJ, Purushotham AD, Barber RW, Ballinger JR, et al. Variation in lymphatic function may predispose to development of breast cancer-related lymphoedema. Eur J Surg Oncol. 2004;30(5):508–14.
Andersen L, Hojris I, Erlandsen M, Andersen J. Treatment of breast-cancer-related lymphedema with or without manual lymphatic drainage: a randomized study. Acta Oncol. 2000;39(3):399–405.
Johansson K, Albertsson M, Ingvar C, Ekdahl C. Effects of compression bandaging with or without manual lymph drainage treatment in patients with postoperative arm lymphedema. Lymphology. 1999;32(3):103–110; Comment in: Lymphology. 2000;33:69–70.
Korpon MI, Vacuriu G, Schneider B. Effects of compression therapy in patients after breast cancer surgery. Annual Congresses of the American College of Phlebology. San Diego, California, 2003; Online www.phlebology.org (Annual Meeting Abstracts).
Kligman L, Wong RKC, Johnston M, Laetsch NS. The treatment of lymphedema related to breast cancer: a systematic review and evidence summary. Support Care Cancer. 2004;12(6):421–31.
Yamamoto R, Yamanoto T. Effectiveness of the treatment-phase of two-phase complex decongestive physiotherapy for the treatment of extremity lymphedema. Int J Clin Oncol. 2007;12(6):463–8.
Moseley AL, Carrati CJ, Piller NB. A systematic review of common conservative therapies for arm lymphoedema secondary to breast cancer treatment. Ann Oncol. 2007;18(4):639–46.
Hamner JB, Fleming MD. Lymphedema therapy reduces the volume of edema and pain in patients with breast cancer. Ann Surg Oncol. 2007;14(6):1904–8.
Badger CM, Peacock JL, Mortimer PS. A randomized, controlled, parallel-group clinical trial comparing multilayer bandaging followed by hosiery versus hosiery alone in the treatment of patients with lymphedema of the limb. Cancer. 2000;88(12):2832–7.
Johansson K, Lie E, Ekdahl C, Lindfeldt J. A randomized study comparing manual lymph drainage with sequential pneumatic compression for treatment of postoperative arm lymphedema. Lymphology. 1998;31:56–64.
Swedborg I. Effects of treatment with an elastic sleeve and intermittent pneumatic compression in post-mastectomy patients with lymphoedema of the arm. Scand J Rehabil Med. 1984;16:35–41.
Vignes S, Porcher R, Arrault M, Dupuy A. Factors influencing breast cancer-related lymphedema volume after intensive decongestive physiotherapy. Support Care Cancer. 2010;19:935. doi:10.1007/s00520-010-0906-x.
Modi S, Stanton AWB, Svensson WE, Peters A, Mortimer PS, Levick JR. Human lymphatic pumping measured in healthy and lymphedematous arms by lymphatic congestion lymphoscintigraphy. J Physiol. 2007;583(Pt 1):271–85.
Partsch H, Clark M, Mosti G, et al. Classification of compression bandages: practical aspects. Dermatol Surg. 2008;34(5):600–9.
Damstra RJ, Partsch H. Compression therapy in breast cancer related lymphedema. A randomized controlled, comparative study of relation between volume and interface pressure changesJ Vasc Surg. 2009;49:1256–63.
Brorson H, Svensson H. Complete reduction of lymphoedema of the arm by liposuction after breast cancer. Scand J Plast Reconstr Surg Hand Surg. 1997;31:137–43.
Damstra RJ, Voesten HGJ, Klinkert P, Brorson H. Reduction surgery by circumferential suction-assisted Lipectomy (Brorson method) in end stage breast cancer-related lymphedema: a prospective study. Br J Surg. 2009;96(8):859–64.
Brorson H, Ohlin K, Olsson G, Nilsson M. Adipose tissue dominates chronic arm lymphedema following breast cancer: an analysis using volume rendered CT images. Lymphat Res Biol. 2006;4:199–210.
Megens A, Harris SR. Physical therapist management of lymphedema following treatment for breast cancer: a critical review of its effectiveness. Phys Ther. 1998;78(12):1302–11.
Lymphoedema Framework. Template for practice: compression hosiery in lymphoedema. London: MEP Ltd; 2006.
WHO. International classification of functioning, disability and health: ICF. Geneva: World Health Organization; 2001.
Devoogdt N, Van Kampen M, Geraerts I, Coremans T, Christiaens M-R. Lymphoedema functioning, disability and health questionnaire (lymph-ICF): reliability and validity. Phys Ther. 2011;91(6):944–57.
Gradalski T, Ochalek K, Kurpiewska J. Complex decongestive lymphatic therapy with or without vodder II manual lymph drainage in more severe chronic postmastectomy upper limb lymphedema: a randomized noninferiority prospective study. J Pain Symptom Manag. 2015;50(6):750.
Hayes SC. Role of exercise in the prevention and management of lymphedema after breast cancer. Exerc Sport Sci Rev. 2010;38(1):2.
Anderson RT, Kimmick GG, McCoy TP, Hopkins J, Levine E, Miller G, et al. A randomized trial of exercise on well-being and function following breast cancer surgery: the RESTORE trial. J Cancer Surviv. 2011;6(2):172–81.
Hayes SC, Speck RM, Reimet E, Stark A, Schmitz KH. Does the effect of weight lifting on lymphedema following breast cancer differ by diagnostic method: results from a randomized controlled trial. Breast Cancer Res Treat. 2011;130(1):227–30.
Paramanandam VS, Roberts D. Weight training is not harmful for women with breast cancer-related lymphoedema: a systematic review. J Physiother. 2014;60(3):136–43.
Soran A, D'Angelo G, Begovic M, Ardic F, Harlak A, Samuel Wieand H, et al. Breast cancer-related lymphedema--what are the significant predictors and how they affect the severity of lymphedema? Breast J. 2006;12(6):536–43.
Norman SA, Localio AR, Kallan MJ, Weber AL, Simoes Torpey HA, Potashnik SL, et al. Risk Factors for Lymphedema after Breast Cancer Treatment. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive. Oncology. 2010;19(11):2746.
Park JH, Lee WH, Chung HS. Incidence and risk factors of breast cancer lymphoedema. J Clin Nurs. 2008;17(11):1450–9.
McNeely ML, Peddle CJ, Yurick JL, Dayes IS, Mackey JR. Conservative and dietary interventions for cancer-related lymphedema: a systematic review and meta-analysis. Cancer. 2011;117(6):1136–48.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG
About this chapter
Cite this chapter
Damstra, R.J. (2018). Upper Limb Lymphedema. In: Lee, BB., Rockson, S., Bergan, J. (eds) Lymphedema. Springer, Cham. https://doi.org/10.1007/978-3-319-52423-8_42
Download citation
DOI: https://doi.org/10.1007/978-3-319-52423-8_42
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-52421-4
Online ISBN: 978-3-319-52423-8
eBook Packages: MedicineMedicine (R0)