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Peripheral Nerve Tissue Engineering: An Outlook on Experimental Concepts

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Modern Concepts of Peripheral Nerve Repair

Abstract

The following paragraphs present a compressed overview of the latest developments in peripheral nerve tissue engineering and the main concepts underlying innovative approaches. Since several excellent review articles have been published recently and especially the biomaterial field is frequently bringing up novel developments, the reader with a deeper interest is referred to the specific literature cited in this chapter for more comprehensive information.

This chapter further provides insight in what is important to be considered for the development of novel nerve guidance channels and tissue-engineered nerve implants specifically. In addition, the potential reasons for a rather slow translation of novel approaches into a clinical use are addressed. This chapter concludes with a discussion of experimental evaluation techniques that can be judged as appropriate and comprehensive for preclinical studies on peripheral nerve regeneration and peripheral nerve tissue engineering.

Illustrations: Lena Julie Freund, MSc Animal Biology and Biomedical Science, Aachen, Germany

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Author information

Authors and Affiliations

  1. Institute of Neuroanatomy and Cell Biology, Hannover Medical School, Carl-Neuberg-Str. 1, D-30519, Hannover, Germany

    Kirsten Haastert-Talini Dr. med. vet. (Adjunct Professor)

  2. Center for Systems Neuroscience (ZSN) Hannover, Hannover, Germany

    Kirsten Haastert-Talini Dr. med. vet. (Adjunct Professor)

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  1. Kirsten Haastert-Talini Dr. med. vet.
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Correspondence to Kirsten Haastert-Talini Dr. med. vet. .

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Editors and Affiliations

  1. Hannover Medical School, Institute of Neuroanatomy and Cell Biology, Hannover, Germany

    Kirsten Haastert-Talini

  2. Schriesheim, Germany

    Hans Assmus

  3. Peripheral Nerve Surgery Unit, Department of Neurosurgery, University of Ulm, Günzburg, Bayern, Germany

    Gregor Antoniadis

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Haastert-Talini, K. (2017). Peripheral Nerve Tissue Engineering: An Outlook on Experimental Concepts. In: Haastert-Talini, K., Assmus, H., Antoniadis, G. (eds) Modern Concepts of Peripheral Nerve Repair. Springer, Cham. https://doi.org/10.1007/978-3-319-52319-4_10

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  • DOI: https://doi.org/10.1007/978-3-319-52319-4_10

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-52318-7

  • Online ISBN: 978-3-319-52319-4

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