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Laparoscopic Hemihepatectomy for Hepatocellular Carcinoma

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Case-Based Lessons in the Management of Complex Hepato-Pancreato-Biliary Surgery

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Abstract

Advanced infiltrative hepatocellular carcinoma (HCC) is rarely treated by resection. According to the Barcelona clinic liver cancer (BCLC) algorithm, extensive multifocal disease with or without vascular invasion in patients with preserved liver function is defined as stage B with intermediate HCC or stage C with advanced HCC, and palliative treatments such as transarterial chemoembolization (TACE) and Sorafenib are considered the standard treatment in these stages. The recent Japanese multicenter study with propensity score matching confirms the findings regarding short-term clinical benefits of laparoscopic liver resection (LLR) over open liver resection (OLR) without any compromise of oncologic principles for HCC patients. We describe a case of advanced infiltrative HCC with microscopic portal vein thrombus treated by pure laparoscopic left hepatectomy, and discuss indications for resection of HCC, intraoperative technique, and alternative minimally invasive approach for HCC.

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References

  1. Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet. 2012;379(9822):1245–55.

    Article  PubMed  Google Scholar 

  2. Suehiro T, Sugimachi K, Matsumata T, Itasaka H, Taketomi A, Maeda T. Protein induced by vitamin K absence or antagonist II as a prognostic marker in hepatocellular carcinoma. Comparison with alpha-fetoprotein. Cancer. 1994;73(10):2464–71.

    Article  CAS  PubMed  Google Scholar 

  3. De Gasperi A, Mazza E, Prosperi M. Indocyanine green kinetics to assess liver function: ready for a clinical dynamic assessment in major liver surgery? World J Hepatol. 2016;8(7):355–67.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Takahara T, Wakabayashi G, Beppu T, Aihara A, Hasegawa K, Gotohda N, et al. Long-term and perioperative outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma with propensity score matching: a multi-institutional Japanese study. J Hepatobiliary Pancreat Sci. 2015;22(10):721–7.

    Article  PubMed  Google Scholar 

  5. Wakabayashi G. Laparoscopic liver resection: how far can we go? J Hepatobiliary Pancreat Surg. 2009;16(4):403–4.

    Article  PubMed  Google Scholar 

  6. Sasaki A, Nitta H, Otsuka K, Takahara T, Nishizuka S, Wakabayashi G. Ten-year experience of totally laparoscopic liver resection in a single institution. Br J Surg. 2009;96(3):274–9.

    Article  CAS  PubMed  Google Scholar 

  7. Buell JF, Cherqui D, Geller DA, O’Rourke N, Iannitti D, Dagher I, et al; World Consensus Conference on Laparoscopic Surgery. The international position on laparoscopic liver surgery: The Louisville Statement, 2008. Ann Surg. 2009;250(5):825–30.

    Google Scholar 

  8. Ciria R, Cherqui D, Geller DA, Briceno J, Wakabayashi G. Comparative short-term benefits of laparoscopic liver resection: 9000 cases and climbing. Ann Surg. 2016;263(4):761–77.

    Article  PubMed  Google Scholar 

  9. Huscher CG, Lirici MM, Chiodini S. Laparoscopic liver resections. Semin Laparosc Surg. 1998;5:204–10.

    CAS  PubMed  Google Scholar 

  10. Belli G, Gayet B, Han HS, Wakabayashi G, Kim KH, Cannon R, et al. International Consensus Group for Laparoscopic Liver Surgery. Laparoscopic left hemihepatectomy a consideration for acceptance as standard of care. Surg Endosc. 2013;27(8):2721–6.

    Article  PubMed  Google Scholar 

  11. Dagher I, Gayet B, Tzanis D, Tranchart H, Fuks D, Soubrane O, et al. International experience for laparoscopic major liver resection. J Hepatobiliary Pancreat Sci. 2014;21(10):732–6.

    Article  PubMed  Google Scholar 

  12. Nitta H, Sasaki A, Fujita T, Itabashi H, Hoshikawa K, Takahara T, et al. Laparoscopy-assisted major liver resections employing a hanging technique: the original procedure. Ann Surg. 2010;251(3):450–3.

    Article  PubMed  Google Scholar 

  13. Lin NC, Nitta H, Wakabayashi G. Laparoscopic major hepatectomy: a systematic literature review and comparison of 3 techniques. Ann Surg. 2013;257(2):205–13.

    Article  PubMed  Google Scholar 

  14. Wakabayashi G, Cherqui D, Geller DA, Buell JF, Kaneko H, Han HS, et al. Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka. Ann Surg. 2015;261(4):619–29.

    PubMed  Google Scholar 

  15. Hasegawa Y, Nitta H, Takahara T, Katagiri H, Baba S, Takeda D, et al. Safely extending the indications of laparoscopic liver resection: When should we start laparoscopic major hepatectomy? Surg Endosc. 2016 Jun 10 (Epub ahead of print).

    Google Scholar 

  16. Hasegawa Y, Koffron AJ, Buell JF, Wakabayashi G. Approaches to laparoscopic liver resection: a meta-analysis of the role of hand-assisted laparoscopic surgery and the hybrid technique. J Hepatobiliary Pancreat Sci. 2015;22(5):335–41.

    Article  PubMed  Google Scholar 

  17. Takahara T, Wakabayashi G, Nitta H, Hasegawa Y, Katagiri H, Takeda D, et al. Laparoscopic liver resection for hepatocellular carcinoma with cirrhosis in a single institution. Hepatobiliary Surg Nutr. 2015;4(6):398–405.

    PubMed  PubMed Central  Google Scholar 

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Author information

Authors and Affiliations

  1. Ageo Central General Hospital, 1-10-10 Kashiwaza, Ageo, 362-8588, Japan

    Go Wakabayashi

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  1. Go Wakabayashi
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Correspondence to Go Wakabayashi .

Editor information

Editors and Affiliations

  1. The Ohio State Wexner Medical Center , The Ohio State University School of Medicine , Columbus, Ohio, USA

    Timothy M. Pawlik

  2. Division of General Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA

    Sharon Weber

  3. Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    T. Clark Gamblin

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Wakabayashi, G. (2017). Laparoscopic Hemihepatectomy for Hepatocellular Carcinoma. In: Pawlik, T., Weber, S., Gamblin, T. (eds) Case-Based Lessons in the Management of Complex Hepato-Pancreato-Biliary Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-50868-9_7

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  • DOI: https://doi.org/10.1007/978-3-319-50868-9_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-50867-2

  • Online ISBN: 978-3-319-50868-9

  • eBook Packages: MedicineMedicine (R0)

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