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Control of Ventilation in Obesity

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Mechanical Ventilation in the Critically Ill Obese Patient

Abstract

Eucapnic obesity may be associated with an augmented chemosensitivity which represents a compensatory response to mass loading of the respiratory system. Yet, a small subset of obese subjects who develop daytime hypercapnia demonstrates a blunted respiratory drive. Although secondary to nocturnal hypoventilation and the subsequent development of daytime hypercapnia, this blunted chemosensitivity contributes to the establishment and maintenance of daytime hypercapnia.

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Author information

Authors and Affiliations

  1. ICU at Latseion Burn Center, General Hospital of Eleusis “Thriasion”, Athens, Greece

    Nikolaos Markou M.D. & Heleni Stefanatou M.D.

  2. 1st University Clinic of Pulmonary Medicine, General Hospital of Diseases of the Chest “Sotiria”, Athens, Greece

    Maria Kanakaki M.D.

Authors
  1. Nikolaos Markou M.D.
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  2. Heleni Stefanatou M.D.
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  3. Maria Kanakaki M.D.
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Correspondence to Nikolaos Markou M.D. .

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Editors and Affiliations

  1. Intensive Care and Non Invasive Ventilatory Unit, Hospital Morales Meseguer, Murcia, Spain

    Antonio M. Esquinas

  2. Dept Respiratory and CC Medicine, Schaffner Hospital, Lens, France

    Malcolm Lemyze

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Markou, N., Stefanatou, H., Kanakaki, M. (2018). Control of Ventilation in Obesity. In: Esquinas, A., Lemyze, M. (eds) Mechanical Ventilation in the Critically Ill Obese Patient. Springer, Cham. https://doi.org/10.1007/978-3-319-49253-7_1

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  • DOI: https://doi.org/10.1007/978-3-319-49253-7_1

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