Abstract
Male hypogonadism is a clinical syndrome that results from failure of the testis to produce physiological levels of testosterone and adequate spermatogenesis as a result of disruption of one or more levels of the hypothalamic-pituitary-testicular axis. Diagnosis of hypogonadism can be difficult given that the symptoms and signs are nonspecific and can change depending on age, comorbid illness, severity, and duration of hypogonadism (Bhasin et al., J Clin Endocrinol Metab, 95(6):253, 2010). A thorough history and physical examination will be needed to help determine the etiology.
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Surampudi, V., Swerdloff, R.S. (2017). Hypogonadotropic and Hypergonadotropic Hypogonadism. In: Hohl, A. (eds) Testosterone. Springer, Cham. https://doi.org/10.1007/978-3-319-46086-4_6
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