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Gene and Cell Therapy in Heart Failure

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Current Approach to Heart Failure

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Abstract

This chapter analyzes existing data on experimental studies testing different gene therapy approaches and stem cell-based therapies to target heart failure (HF) treatment. It also reports on the results of the different clinical trials testing these innovative therapeutic approaches and briefly discusses the current needs and future directions of this research field in order to favour its successful translation into the clinical practice.

Funding

his work has been supported by grants from the Spanish Ministry of Economy and Competitiveness of Science [SAF2013-42962-R to L.B; SAF2015-71653-R to GV.]; and Institute of Health Carlos III, ISCIII [TERCEL RD12/0019/0026 and RIC RD12/0042/0027 to L.B.] Spain. We thank FIC-Fundacion Jesús Serra, Barcelona, Spain, for their continuous support.

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Authors and Affiliations

  1. Cardiovascular Research Center (CSIC-ICCC) and Biomedical Research Institute Sant Pau (IIB-Sant Pau), Hospital de la Sant Creu I Sant Pau, Barcelona, Spain

    Lina Badimon, Gemma Vilahur & Judit Cubedo

  2. Cardiovascular Research Chair UAB, c/Sant Antoni MaClaret 167, 08025, Barcelona, Spain

    Lina Badimon, Gemma Vilahur & Judit Cubedo

Authors
  1. Lina Badimon
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  2. Gemma Vilahur
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  3. Judit Cubedo
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Correspondence to Lina Badimon .

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Editors and Affiliations

  1. Emergency Clinical Hospital of Bucharest, UMF Carol Davila – Bucharest Emergency Clinical Hospital of Bucharest, Bucharest, Romania

    Maria Dorobanţu

  2. Department of Cardiology, University Heart Center Department of Cardiology, Zürich, Switzerland

    Frank Ruschitzka

  3. Section of Cardiovascular Diseases, University of Brescia Section of Cardiovascular Diseases, Brescia, Italy

    Marco Metra

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Badimon, L., Vilahur, G., Cubedo, J. (2016). Gene and Cell Therapy in Heart Failure. In: Dorobanţu, M., Ruschitzka, F., Metra, M. (eds) Current Approach to Heart Failure. Springer, Cham. https://doi.org/10.1007/978-3-319-45237-1_16

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  • DOI: https://doi.org/10.1007/978-3-319-45237-1_16

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