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Pathology of Ischemic Heart Disease

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Congestive Heart Failure and Cardiac Transplantation

Abstract

Ischemic heart disease is a broad term encompassing several closely related syndromes caused by myocardial ischemia, an imbalance between cardiac blood supply perfusion and myocardial oxygen and nutritional requirements.

Responsible for seven million deaths worldwide each year, ischemic heart disease is the leading cause of death in the United States and other developed countries. It is most often caused by thrombotic occlusion of a high-risk coronary plaque that leads to myocardial infarction or cardiac death or embolization from a high-risk coronary plaque. This chapter focuses on coronary atherosclerosis, acute myocardial infarction, and left ventricular failure and healed myocardial infarction. It includes detailed descriptions of the various disease processes and clinical manifestations, results from and implications based on numerous research studies, and treatment options and expected outcomes.

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Author information

Authors and Affiliations

  1. Division of Cardiovascular Medicine, University of Minnesota, Minnesota, MN, 55455, USA

    Zeev Vlodaver MD

  2. Cardiology, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN, 55415, USA

    Richard W. Asinger MD

  3. Department of Cardiology, Abbott Northwestern Hospital, 920 E. 28th Street, Minneapolis, MN, 55407, USA

    John R. Lesser MD

Authors
  1. Zeev Vlodaver MD
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  2. Richard W. Asinger MD
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  3. John R. Lesser MD
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Corresponding author

Correspondence to John R. Lesser MD .

Editor information

Editors and Affiliations

  1. Lillehei Heart Institute, Department of Medicine, University of Minnesota Medical Center, University of Minnesota, Minneapolis, Minnesota, USA

    Daniel J. Garry

  2. Division of Cardiovascular Medicine, University of Minnesota, Minneapolis, Minnesota, USA

    Robert F. Wilson

  3. Division of Cardiovascular Medicine, University of Minnesota, Minneapolis, Minnesota, USA

    Zeev Vlodaver

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Vlodaver, Z., Asinger, R.W., Lesser, J.R. (2017). Pathology of Ischemic Heart Disease. In: Garry, D., Wilson, R., Vlodaver, Z. (eds) Congestive Heart Failure and Cardiac Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-44577-9_4

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  • DOI: https://doi.org/10.1007/978-3-319-44577-9_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-44575-5

  • Online ISBN: 978-3-319-44577-9

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