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Bioactive Materials: Definitions and Application in Tissue Engineering and Regeneration Therapy

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Biocompatible Glasses

Part of the book series: Advanced Structured Materials ((STRUCTMAT,volume 53))

Abstract

The field of biomaterials has been evolving at an astonished rate in the last decades, leading to the design of bioactive materials, materials able to elicit specific and predictable cells and tissues responses. This chapter will go through the key milestones achieved during this exciting development with special emphasis on the meaning of material-driven bioactivity and its importance in the optimization of highly performing tissue regeneration and regeneration therapy methodologies. An overview on the history of bioactive glasses (bioglasses) (please consult the Editor’s note in order to clarify the usage of the terms bioglass, bioactive glass and biocompatible glass) and their biological properties will describe the huge potential of these materials in regenerative medicine applications. Finally, an introduction on stem cells and their role in the physiological development of tissues and organs will be given, shedding light on therapeutic synergistic approaches based on the use of bioactive materials and stem cells.

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Acknowledgments

Arghya Paul would like to acknowledge the Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of National Institutes of Health (NIH), under Award Number P20GM103638-04 and University of Kansas New Faculty General Research Fund. Alessandro Polini would like to acknowledge the Radboud Excellence Initiative from Radboud University for funding.

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Authors and Affiliations

  1. BioIntel Research Laboratory, Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, School of Engineering, University of Kansas, Lawrence, KS, USA

    Jon Whitlow & Arghya Paul

  2. Radboud Excellence Initiative, Radboud University, Nijmegen, The Netherlands

    Alessandro Polini

  3. Department of Biomaterials, Radboud University Medical Center, Nijmegen, The Netherlands

    Alessandro Polini

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  1. Jon Whitlow
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  2. Arghya Paul
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  3. Alessandro Polini
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Correspondence to Alessandro Polini .

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Editors and Affiliations

  1. Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, Brazil

    Juliana Marchi

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Whitlow, J., Paul, A., Polini, A. (2016). Bioactive Materials: Definitions and Application in Tissue Engineering and Regeneration Therapy. In: Marchi, J. (eds) Biocompatible Glasses. Advanced Structured Materials, vol 53. Springer, Cham. https://doi.org/10.1007/978-3-319-44249-5_1

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