Abstract
A 26-week-old ex-28-week premature infant presents for the resection of a congenital pulmonary adenomatous malformation (CPAM). He is intubated and sedated in the Neonatal Intensive Care Unit (NICU). You notice that the patient’s hemoglobin is 7 and his hematocrit is 21. The NICU fellow giving you the report informs you that in preparation for the upcoming surgery the patient was transfused with fresh frozen plasma “just to give him volume” (which doesn’t seem like a good reason to you) and is ready for the operation. You tell the fellow that this critically ill neonate needs to have hemoglobin of at least 10.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Lacroix J, Hébert PC, Hutchison JS, Hume HA, Tucci M, Ducruet T, et al. TRIPICU Investigators, Canadian Critical Care Trials Group, Pediatric Acute Lung Injury and Sepsis Investigators Network, et al. Transfusion strategies for patients in pediatric intensive care units. N Engl J Med. 2007;356:1609–19.
Hébert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, et al. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med. 1999;340(6):409–17.
Kirpalani H, Whyte RK, Andersen C, Asztalos EV, Heddle N, Blajchman MA, et al. The premature infants in need of transfusion (PINT) study: a randomized, controlled trial of restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants. J Pediatr. 2006;149:301–7.
Aher SM, Ohlsson A. Late erythropoetin for preventing red blood cell transfusion in preterm and/or low birth weight infants. Cochrane Database Syst Rev. 2014;4:CD004868.
Ohls RK, Kamath-Rayne BD, Christensen RD, Wiedmeier SE, Rosenberg A, Fuller J, et al. Cognitive outcomes of preterm infants randomized to darbepoetin, erythropoietin or placebo. Pediatrics. 2014;133:1023–30.
Weiskopf RB, Kramer JH, Viele M, Neumann M, Feiner JR, Watson JJ, Hopf HW, Toy P. Acute severe isovolemic anemia impairs cognitive function and memory in humans. Anesthesiology. 2000;92(6):1646–52.
van Hoften JCR, Verhagen EA, Keating P. Cerebral tissue oxygen saturation and extraction in preterm infants before and after blood transfusion. Arch Dis Child Fetal Neonatat. 2010;95:F352–8.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Albert, O.N. (2017). Are the Transfusion Goals for a Premature Infant the Same As for a 7-Year-Old?. In: Scher, C., Clebone, A., Miller, S., Roccaforte, J., Capan, L. (eds) You’re Wrong, I’m Right. Springer, Cham. https://doi.org/10.1007/978-3-319-43169-7_39
Download citation
DOI: https://doi.org/10.1007/978-3-319-43169-7_39
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-43167-3
Online ISBN: 978-3-319-43169-7
eBook Packages: MedicineMedicine (R0)