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The Current Situation and Experience of Multidisciplinary Treatment of Soft Tissue Sarcoma in China

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Sarcoma

Abstract

Soft tissue sarcoma (STS) is a malignant tumor of soft tissue, more common in the limbs, trunk, and retroperitoneal body wall. STS relapses after incomplete excision, and the repeated resections of recurrence lesions may result in accelerating life-threatening tumor metastasis. Currently, how to reduce the recurrence rate and the retention and restoration of good function have become the pursuits of clinical research of STS. Because STS may occur anywhere in the body, with various histologic subtypes, and variable clinical characteristics, analysis of outcomes remains challenging. Current research efforts include: (1) anatomy of related tissue that sarcoma may grow in, (2) retention of normal tissue while obtaining a negative resection margin, and (3) application of comprehensive treatments and functional reconstruction of damaged tissues. The goals are to reduce the recurrence rate, improve function, and control distant metastasis for the purpose of long-term survival.

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References

  1. Cormier JN, Pollock RE. Soft tissue sarcomas. CA Cancer J Clin. 2004;54:94–109.

    Article  PubMed  Google Scholar 

  2. Rydholm A. Improving the management of soft tissue sarcoma. Diagnosis and treatment should be given in specialist centres. BMJ. 1998;317:93–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Italiano A, Mathoulin-Pelissier S, Cesne AL, Terrier P, Bonvalot S, et al. Trends in survival for patients with metastatic soft-tissue sarcoma. Cancer. 2011;117:1049–54.

    Article  PubMed  Google Scholar 

  4. Christie-Large M, James SL, Tiessen L, Davies AM, Grimer RJ. Imaging strategy for detecting lung metastases at presentation in patients with soft tissue sarcomas. Eur J Cancer. 2008;44:1841–5.

    Article  CAS  PubMed  Google Scholar 

  5. Conrad 3rd EU, Morgan HD, Vernon C, Schuetze SM, Eary JF. Fluorodeoxyglucose positron emission tomography scanning: basic principles and imaging of adult soft-tissue sarcomas. J Bone Joint Surg Am. 2004;86-A(Suppl 2):98–104.

    Google Scholar 

  6. Strauss DC, Qureshi YA, Hayes AJ, Thway K, Fisher C, et al. The role of core needle biopsy in the diagnosis of suspected soft tissue tumours. J Surg Oncol. 2010;102:523–9.

    Article  CAS  PubMed  Google Scholar 

  7. AJCC cancer staging manual, 7th edn, New York: Springer; 2009.

    Google Scholar 

  8. Enneking WF, Spanier SS, Goodman MA. A system for the surgical staging of musculoskeletal sarcoma. Clin Orthop Relat Res. 1980;153:106–20.

    Google Scholar 

  9. Enneking WF, Spanier SS, Goodman MA. A system for the surgical staging of musculoskeletal sarcoma. 1980. Clin Orthop Relat Res. 2003;415:4–18.

    Article  Google Scholar 

  10. O'Sullivan B, Davis AM, Turcotte R, Bell R, Catton C, et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. Lancet. 2002;359:2235–41.

    Article  PubMed  Google Scholar 

  11. Gortzak E, Azzarelli A, Buesa J, Bramwell VH, van Coevorden F, et al. A randomised phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma. Eur J Cancer. 2001;37:1096–103.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Chunlin Zhang M.D. .

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Zhang, C., Zhu, Z., Zhu, K.P. (2017). The Current Situation and Experience of Multidisciplinary Treatment of Soft Tissue Sarcoma in China. In: Henshaw, R. (eds) Sarcoma. Springer, Cham. https://doi.org/10.1007/978-3-319-43121-5_28

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  • DOI: https://doi.org/10.1007/978-3-319-43121-5_28

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-43119-2

  • Online ISBN: 978-3-319-43121-5

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