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Hydrocephalus in the Elderly: Surgical Management of Idiopathic Normal Pressure Hydrocephalus

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Brain and Spine Surgery in the Elderly

Abstract

Idiopathic normal pressure hydrocephalus (iNPH) was first described by Dr. Salomon Hakim in 1964 as a clinical triad of gait disturbance, cognitive difficulties, and urinary incontinence, associated with abnormal ventricular dilatation, despite normal cerebrospinal fluid (CSF) pressures. In the 1960s, Dr. Hakim and his colleagues demonstrated the effectiveness of CSF diversion surgery (shunting) for patients with iNPH, which to date has remained the only recommended modality of treatment for the disease. This chapter will also briefly review the issues associated with the limited role for endoscopic third ventriculostomy (ETV) and pharmacologic agents (drugs) in the treatment of patients with iNPH.

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References

  1. Adams RD (1966) Further observations on normal pressure hydrocephalus. Proc R Soc Med 59:1135–1140

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Adams RD, Fisher CM, Hakim S, Ojemann RG, Sweet WH (1965) Symptomatic occult hydrocephalus with “normal” cerebrospinal-fluid pressure.a treatable syndrome. N Engl J Med 273:117–126

    Article  CAS  PubMed  Google Scholar 

  3. Ageno W, Gallus AS, Wittkowsky A, Crowther M, Hylek EM, Palareti G (2012) Oral anticoagulant therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141:e44S–e88S

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Aimard G, Vighetto A, Gabet JY, Bret P, Henry E (1990) Acetazolamide: an alternative to shunting in normal pressure hydrocephalus? Preliminary results. Rev Neurol (Paris) 146:437–439

    CAS  Google Scholar 

  5. Alperin N, Oliu CJ, Bagci AM, Lee SH, Kovanlikaya I, Adams D et al (2014) Low-dose acetazolamide reverses periventricular white matter hyperintensities in iNPH. Neurology 82:1347–1351

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Andrén K, Wikkelsø C, Tisell M, Hellström P (2014) Natural course of idiopathic normal pressure hydrocephalus. J Neurol Neurosurg Psychiatr 85:806–810

    Article  PubMed  Google Scholar 

  7. Aparici-Robles F, Molina-Fabrega R (2008) Abdominal cerebrospinal fluid pseudocyst: a complication of ventriculoperitoneal shunts in adults. J Med Imaging Radiation Oncol 52:40–43

    Article  CAS  Google Scholar 

  8. Argo JL, Yellumahanthi DK, Ballem N, Harrigan MR, Fisher WS, Wesley MM et al (2009) Laparoscopic versus open approach for implantation of the peritoneal catheter during ventriculoperitoneal shunt placement. Surg Endosc 23:1449–1455

    Article  PubMed  Google Scholar 

  9. Aschoff A, Kremer P, Hashemi B, Kunze S (1999) The scientific history of hydrocephalus and its treatment. Neurosurg Rev 22:67–95

    Google Scholar 

  10. Azeem SS, Origitano TC (2007) Ventricular catheter placement with a frameless neuronavigational system. Neurosurgery 60:243–248

    PubMed  Google Scholar 

  11. Bandeen-Roche K, Xue Q-L, Ferrucci L, Walston J, Guralnik JM, Chaves P et al (2006) Phenotype of frailty: characterization in the women’s health and aging studies. J Gerontol A Biol Sci Med Sci 61:262–266

    Article  PubMed  Google Scholar 

  12. Bani A, Telker D, Hassler W, Grundlach M (2006) Minimally invasive implantation of the peritoneal catheter in ventriculoperitoneal shunt placement for hydrocephalus: analysis of data in 151 consecutive adult patients. J Neurosurg 105:869–872

    Article  PubMed  Google Scholar 

  13. Basati SS, Harris TJ, Linninger AA (2011) Dynamic brain phantom for intracranial volume measurements. IEEE Trans Biomed Eng 58:1450–1455

    Article  PubMed  Google Scholar 

  14. Benzel EC, Pelletier AL, Levy PG (1990) Communicating hydrocephalus in adults: prediction of outcome after ventricular shunting procedures. Neurosurgery 26:655–660

    Article  CAS  PubMed  Google Scholar 

  15. Bergsneider M, Black PM, Klinge P, Marmarou A, Relkin N (2005) Surgical management of idiopathic normal-pressure hydrocephalus. Neurosurgery 57(3 Suppl):S29–S39

    PubMed  Google Scholar 

  16. Bergsneider M, Lee S, Judy JW (2008) Self-Clearing Catheter for Clinical Implantation, Google Patents

    Google Scholar 

  17. Bergsneider M, Miller C, Vespa PM, Hu X (2008) Surgical management of adult hydrocephalus. Neurosurgery 62(Suppl 2):643–660

    Google Scholar 

  18. Boon AJ, Tans JT, Delwel EJ, Egeler-Peerdeman SM, Hanlo PW, Wurzer HA et al (1998) Dutch Normal-Pressure Hydrocephalus Study: randomized comparison of low- and medium-pressure shunts. J Neurosurg 88:490–495

    Article  CAS  PubMed  Google Scholar 

  19. Boyd JB, Bradford B, Watne AL (1980) Operative risk factors of colon resection in the elderly. Ann Surg 192:743–746

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Bradley WG (2000) Normal pressure hydrocephalus: new concepts on etiology and diagnosis. AJNR Am J Neuroradiol 21(9):1586–1590

    CAS  PubMed  Google Scholar 

  21. Bullara, LA (1978) Implantable pressure transducer, Google Patents

    Google Scholar 

  22. Casmiro M, D’Alessandro R, Cacciatore FM, Daidone R, Calbucci F, Lugaresi E (1989) Risk factors for the syndrome of ventricular enlargement with gait apraxia (idiopathic normal pressure hydrocephalus): a case–control study. J Neurol Neurosurg Psychiatr 52:847–852

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Chow WB, Rosenthal RA, Merkow RP, Ko CY, Esnaola NF, American College of Surgeons National Surgical Quality Improvement Program et al (2012) Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American College of Surgeons National Surgical Quality Improvement Program and the American Geriatrics Society. J Am Coll Surg 215:453–466

    Article  PubMed  Google Scholar 

  24. Crowley RW, Dumont AS, Asthagiri AR, Torner JC, Medel R, Jane JA et al (2014) Intraoperative ultrasound guidance for the placement of permanent ventricular cerebrospinal fluid shunt catheters: a single-center historical cohort study. World Neurosurg 81:397–403

    Article  PubMed  Google Scholar 

  25. Del Bigio MR, Di Curzio DL (2016) Nonsurgical therapy for hydrocephalus: a comprehensive and critical review. Fluids Barriers CNS 13:1–20

    Google Scholar 

  26. Devereaux PJ, Cohn SL, Eagle KA (2016) Management of cardiac risk for noncardiac surgery. In: Post TW (ed) UpToDate, 5 edn. UpToDate, Waltham, pp 1–14

    Google Scholar 

  27. Devereaux PJ, Goldman L, Cook DJ (2005) Perioperative cardiac events in patients undergoing noncardiac surgery: a review of the magnitude of the problem, the pathophysiology of the events and methods to estimate and communicate risk. CMAJ 173(6):627–634

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  28. Douketis JD (2011) Perioperative management of patients who are receiving warfarin therapy: an evidence-based and practical approach. Blood 117:5044–5049

    Article  CAS  PubMed  Google Scholar 

  29. Douketis JD, Spyropoulos AC, Spencer FA, Mayr M, Jaffer AK, Eckman MH et al (2012) Perioperative management of antithrombotic therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141:e326S–e350S

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Drake JM, Sainte-Rose C (1995) The Shunt Book. Wiley-Blackwell, Cambridge

    Google Scholar 

  31. Eide PK, Sorteberg W (2010) Diagnostic intracranial pressure monitoring and surgical management in idiopathic normal pressure hydrocephalus: a 6-year review of 214 patients. Neurosurgery 66:80–91

    Article  PubMed  Google Scholar 

  32. Eide PK, Sorteberg W (2016) Outcome of surgery for idiopathic normal pressure hydrocephalus: role of preoperative static and pulsatile intracranial pressure. World Neurosurg 86:186–193.e1

    Article  PubMed  Google Scholar 

  33. Eklund A, Smielewski P, Chambers I, Alperin N, Malm J, Czosnyka M et al (2007) Assessment of cerebrospinal fluid outflow resistance. Med Biol Eng Comput 45:719–735

    Article  PubMed  Google Scholar 

  34. Filsoufi F, Rahmanian PB, Castillo JG, Chikwe J, Silvay G, Adams DH (2008) Excellent early and late outcomes of aortic valve replacement in people aged 80 and older. J Am Geriatr Soc 56:255–261

    Article  PubMed  Google Scholar 

  35. Finlayson E, Fan Z, Birkmeyer JD (2007) Outcomes in octogenarians undergoing high-risk cancer operation: A National Study. J Am Coll Surg 205:729–734

    Article  PubMed  Google Scholar 

  36. Fox BD, Kahn SR, Langleben D, Eisenberg MJ, Shimony A (2012) Efficacy and safety of novel oral anticoagulants for treatment of acute venous thromboembolism: direct and adjusted indirect meta-analysis of randomised controlled trials. BMJ 345:e7498

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  37. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J et al (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56:M146–M156

    Article  CAS  PubMed  Google Scholar 

  38. Gangemi M, Maiuri F, Buonamassa S, Colella G, de Divitiis E (2004) Endoscopic third ventriculostomy in idiopathic normal pressure hydrocephalus. Neurosurgery 55:129–134

    Google Scholar 

  39. Gölz L, Ruppert F-H, Meier U, Lemcke J (2014) Outcome of modern shunt therapy in patients with idiopathic normal pressure hydrocephalus 6 years postoperatively. J Neurosurg 121:771–775

    Article  PubMed  Google Scholar 

  40. Greenberg MS (2010) Handbook of Neurosurgery. Thieme, New York, pp 207–212

    Google Scholar 

  41. Group PS (2008) Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet 371(9627):1839–1847

    Article  CAS  Google Scholar 

  42. Gustafson L, Hagberg B (1978) Recovery in hydrocephalic dementia after shunt operation. J Neurol Neurosurg Psychiatr 41:940–947

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  43. Hakim S, Adams RD (1965) The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. Observations on cerebrospinal fluid hydrodynamics. J Neurol Sci 2:307–327

    Article  CAS  PubMed  Google Scholar 

  44. Hakim S (1964) Algunas Observaciones Sobre La Presión Del L.C.R. Síndrome Hidrocefálico en El Adulto Con Presión Normal Del L.C.R.: (Presentación De Un Nuevo Síndrome). Javeriana University School of Medicine, Bogotá (Doctoral Thesis)

    Google Scholar 

  45. Halperin JJ, Kurlan R, Schwalb JM, Cusimano MD, Gronseth G, Gloss D (2015) Practice guideline: idiopathic normal pressure hydrocephalus: response to shunting and predictors of response: report of the guideline development, dissemination, and implementation subcommittee of the American Academy of Neurology. Neurology 85:2063–2071

    Article  PubMed  PubMed Central  Google Scholar 

  46. Hamilton M, Couldwell WT, Golfinos JG (2014) Handbook of bleeding and coagulation for neurosurgery

    Google Scholar 

  47. Hashimoto M, Ishikawa M, Mori E, Kuwana N (2010) Diagnosis of idiopathic normal pressure hydrocephalus is supported by MRI-based scheme: a prospective cohort study. Cerebrospinal Fluid Res 7(1):18

    Google Scholar 

  48. Haynes IS (1913) I. Congenital internal hydrocephalus: its treatment by drainage of the cisterna magna into the cranial sinuses. Ann Surg 57:449–484

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  49. Healey JS, Eikelboom J, Douketis J, Wallentin L, Oldgren J, Yang S et al (2012) Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the randomized evaluation of long-term anticoagulation therapy (RE-LY) randomized trial. Circulation 126:343–348

    Article  CAS  PubMed  Google Scholar 

  50. Higgs Z, Macafee D, Braithwaite BD, Maxwell-Armstrong CA (2005) The Seldinger technique: 50 years on. Lancet 366:1407–1409

    Article  CAS  Google Scholar 

  51. Hirsch IB, McGill JB, Cryer PE, White PF (1991) Perioperative management of surgical patients with diabetes mellitus. Anesthesiology 74:346–359

    Article  CAS  PubMed  Google Scholar 

  52. Hollenberg M, Mangano DT, Browner WS, London MJ, Tubau JF, Tateo IM (1992) Predictors of postoperative myocardial ischemia in patients undergoing noncardiac surgery. The Study of Perioperative Ischemia Research Group. JAMA 268:205–209

    Article  CAS  PubMed  Google Scholar 

  53. Huie F, Sayad P, Usal H, Hayek N, Arbit E, Ferzli G (1999) Laparoscopic transabdominal lumboperitoneal shunt. Surg Endosc 13:161–163

    Article  CAS  PubMed  Google Scholar 

  54. Hydrocephalus Association (2016) Shunt systems for the management of hydrocephalus. Shunt Systems, from http://www.hydroassoc.org/shunt-systems/

  55. Isaacs AM, Bezchlibnyk YB, Yong H, Koshy D, Urbaneja G, Hader W et al (2016) Endoscopic third ventriculostomy for treatment of adult hydrocephalus: long-term follow up of 163 patients. Neurosurg Focus 41(3):E3

    Article  PubMed  Google Scholar 

  56. Ishii K, Hashimoto M, Hayashida K, Hashikawa K, Chang C-C, Nakagawara J et al (2011) A multicenter brain perfusion SPECT study evaluating idiopathic normal-pressure hydrocephalus on neurological improvement. Dement Geriatr Cogn Disord 32:1–10

    Article  PubMed  Google Scholar 

  57. Ishikawa M, Hashimoto M, Kuwana N, Mori E, Miyake H, Wachi A et al (2008) Guidelines for management of idiopathic normal pressure hydrocephalus. Neurol Med Chir (Tokyo) 48 Suppl:S1–S23

    Article  Google Scholar 

  58. Jacobs L (1977) Diabetes mellitus in normal pressure hydrocephalus. J Neurol Neurosurg Psychiatr 40:331–335

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  59. Jenkinson MD, Gamble C, Hartley JC, Hickey H (2014) The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol. Trials 15:4

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  60. Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC), European Association for Cardio-Thoracic Surgery (EACTS), Vahanian A, Alfieri O, Andreotti F, Antunes MJ, et al (2012) Guidelines on the management of valvular heart disease (version 2012). Eur Heart J 33:2451–2496

    Google Scholar 

  61. Jung N, Kim D (2013) Effect of electromagnetic navigated ventriculoperitoneal shunt placement on failure rates. J Korean Neurosurg Soc 53:150–155

    Article  PubMed  PubMed Central  Google Scholar 

  62. Kahlon B, Sjunnesson J, Rehncrona S (2007) Long−term outcome in patients with suspected normal pressure hydrocephalus. Neurosurgery 60:327

    Article  PubMed  Google Scholar 

  63. Kanemoto H, Kazui H, Suzuki Y, Sato S, Kishima H, Yoshimine T et al (2016) Effect of lumbo-peritoneal shunt surgery on neuropsychiatric symptoms in patients with idiopathic normal pressure hydrocephalus. J Neurol Sci 361:206–212

    Article  PubMed  Google Scholar 

  64. Katlic MR (2010) Consider surgery for elderly patients. CMAJ 182:1403–1404

    Article  PubMed  PubMed Central  Google Scholar 

  65. Katlic MR (2013) The holy grail of geriatric surgery. Ann Surg 257:1005–1006

    Article  PubMed  Google Scholar 

  66. Kavic SM, Segan RD, Taylor MD, Roth JS (2007) Laparoscopic management of ventriculoperitoneal and lumboperitoneal shunt complications. JSLS 11:14–19

    PubMed  PubMed Central  Google Scholar 

  67. Kaw R, Chung F, Pasupuleti V, Mehta J, Gay PC, Hernandez AV (2012) Meta-analysis of the association between obstructive sleep apnoea and postoperative outcome. Br J Anaesth 109:897–906

    Article  CAS  PubMed  Google Scholar 

  68. Kawahara T, Tokimura H, Higa N, Hirano H, Bohara M (2013) Surgical technique for preventing subcutaneous migration of distal lumboperitoneal shunt catheters. Innovative Neurosurg 1(3–4):169–172

    Google Scholar 

  69. Kazui H, Miyajima M, Mori E, Ishikawa M (2015) Lumboperitoneal shunt surgery for idiopathic normal pressure hydrocephalus (SINPHONI-2): an open-label randomised trial. Lancet Neurol 14:585–594

    Google Scholar 

  70. Kestle JRW, Drake JM, Cochrane DD, Milner R, Walker ML, Abbott R et al (2003) Lack of benefit of endoscopic ventriculoperitoneal shunt insertion: a multicenter randomized trial. J Neurosurg 98:284–290

    Article  PubMed  Google Scholar 

  71. Kestle JRW, Holubkov R, Douglas Cochrane D, Kulkarni AV, Limbrick DD, Luerssen TG et al (2016) A new hydrocephalus clinical research network protocol to reduce cerebrospinal fluid shunt infection. J Neurosurg Pediatr 17(4):391–396

    Article  PubMed  Google Scholar 

  72. Khosrovi H, Kaufman HH, Hrabovsky E, Bloomfield SM, Prabhu V, el-Kadi HA (1998) Laparoscopic-assisted distal ventriculoperitoneal shunt placement. Surg Neurol 49:127–135

    Google Scholar 

  73. Kilic K (2010) Predicting the outcome of shunt surgery in normal pressure hydrocephalus. Neurosurgery 66:E1217; author reply E1217

    Article  PubMed  Google Scholar 

  74. Kim YT, Kim JY (2015) Shunt for the hydrocephalus: the past and the present. Inter Student’s J

    Google Scholar 

  75. Kirshtein B, Benifla M, Roy-Shapira V, Merkin V, Melamed I, Cohen Z, Cohen A (2004) “Laparoscopically guided distal ventriculoperitoneal shunt placement.” Surg Laparosc Endosc Percutan Tech 14(5):276–278

    Google Scholar 

  76. Klinge P, Hellström P, Tans J, Wikkelsø C (2012) European iNPH Multicentre Study Group: one-year outcome in the European multicentre study on iNPH. Acta Neurol Scand 126:145–153

    Article  CAS  PubMed  Google Scholar 

  77. Klinge P, Marmarou A, Bergsneider M, Relkin N, Black PM (2005) Outcome of shunting in idiopathic normal-pressure hydrocephalus and the value of outcome assessment in shunted patients. Neurosurgery 57:S40–S52

    Article  PubMed  Google Scholar 

  78. Kluge S, Baumann HJ, Regelsberger J, Kehler U, Gliemroth J, Koziej B et al (2010) Pulmonary hypertension after ventriculoatrial shunt implantation. J Neurosurg 113:1279–1283

    Article  PubMed  Google Scholar 

  79. Krauss JK, Regel JP, Vach W, Droste DW, Borremans JJ, Mergner T (1996) Vascular risk factors and arteriosclerotic disease in idiopathic normal-pressure hydrocephalus of the elderly. Stroke 27:24–29

    Google Scholar 

  80. Kurtom KH, Magram G (2007) Siphon regulatory devices: their role in the treatment of hydrocephalus. Neurosurg Focus 22:1–8

    Article  Google Scholar 

  81. Landesberg G, Beattie WS, Mosseri M, Jaffe AS (2009) Perioperative myocardial infarction. Circulation 119(22):2936–2944

    Article  PubMed  Google Scholar 

  82. Lane JD, Mugamba J, Ssenyonga P, Warf BC (2014) Effectiveness of the bactiseal universal shunt for reducing shunt infection in a sub-Saharan African context: a retrospective cohort study in 160 Ugandan children. J Neurosurg Pediatr 13:140–144

    Article  PubMed  Google Scholar 

  83. Larsson A, Wikkelsø C, Bilting M, Stephensen H (1991) Clinical parameters in 74 consecutive patients shunt operated for normal pressure hydrocephalus. Acta Neurol Scand 84:475–482

    Article  CAS  PubMed  Google Scholar 

  84. Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF et al (1999) Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation 100:1043–1049

    Article  CAS  PubMed  Google Scholar 

  85. Li B, Zhang Q, Liu J, Yu H, Hu S (2009) Clinical application of a laparoscope in ventri‐peritoneal shunting. Minim Invasive Ther Allied Technol 16:367–369

    Article  CAS  Google Scholar 

  86. Linninger A, Basati S, Dawe R, Penn R (2009) An impedance sensor to monitor and control cerebral ventricular volume. Med Eng Phys 31:838–845

    Article  PubMed  PubMed Central  Google Scholar 

  87. Lip GY, Douketis JD (2016) Perioperative management of patients receiving anticoagulants. In: Post TW, Leung LL, Timaeur JS (eds) UpToDate, 5 edn. UpToDate, Waltham, pp 1–42

    Google Scholar 

  88. Lockhart EM, Willingham MD, Abdallah AB, Helsten DL, Bedair BA, Thomas J et al (2013) Obstructive sleep apnea screening and postoperative mortality in a large surgical cohort. Sleep Med 14:407–415

    Article  PubMed  PubMed Central  Google Scholar 

  89. Ludin L, Mauge C (2012) Programmable shunt with electromechanical valve actuator, Codman & Shurtleff, Inc

    Google Scholar 

  90. Makary MA, Segev DL, Pronovost PJ, Syin D, Bandeen-Roche K, Patel P et al (2010) Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg 210(6):901–908

    Google Scholar 

  91. Marmarou A, Bergsneider M, Klinge P, Relkin N, Black PM (2005) The value of supplemental prognostic tests for the preoperative assessment of idiopathic normal-pressure hydrocephalus. Neurosurgery 57(3 Suppl):S17–S28

    PubMed  Google Scholar 

  92. Marmarou A, Bergsneider M, Relkin N, Klinge P, Black PM (2005) Development of guidelines for idiopathic normal-pressure hydrocephalus: introduction. Neurosurgery 57(3 Suppl):S1–S3

    PubMed  Google Scholar 

  93. Marmarou A, Black P, Bergsneider M, Klinge P, Relkin N (2005) Guidelines for management of idiopathic normal pressure hydrocephalus: progress to date. Acta Neurochir Suppl 95:237–240

    Google Scholar 

  94. Marmarou A, Young HF, Aygok GA, Sawauchi S (2005) Diagnosis and management of idiopathic normal-pressure hydrocephalus: a prospective study in 151 patients. J Neurosurg 102(6):987–997

    Article  PubMed  Google Scholar 

  95. McGovern RA, Kelly KM, Chan AK, Morrissey NJ, McKhann GM (2014) Should ventriculoatrial shunting be the procedure of choice for normal-pressure hydrocephalus? J Neurosurg 120:1458–1464

    Article  PubMed  Google Scholar 

  96. Meier U, Mutze S (2004) Correlation between decreased ventricular size and positive clinical outcome following shunt placement in patients with normal-pressure hydrocephalus. J Neurosurg 100:1036–1040. http://dx.doi.org/103171/jns200410061036

  97. Meltzer H (2011) Insertion of Ventriculoperitoneal Shunt. In: Jandial R, McCormick P, Black P. Core Techniques in Operative Neurosurgery. Elsevier Saunders. Philadelphia, PA

    Google Scholar 

  98. Milton CA, Sanders P, Steele PM (2001) Late cardiopulmonary complication of ventriculo-atrial shunt. Lancet 358(9293):1608

    Article  CAS  PubMed  Google Scholar 

  99. Mitchell P, Mathew B (1999) Third ventriculostomy in normal pressure hydrocephalus. Br J Neurosurg 13:382–385

    Article  CAS  PubMed  Google Scholar 

  100. Miyajima M, Kazui H, Mori E, Ishikawa M (2016) One-year outcome in patients with idiopathic normal-pressure hydrocephalus: comparison of lumboperitoneal shunt to ventriculoperitoneal shunt. J Neurosurg: 1–10

    Google Scholar 

  101. Mokhlesi B, Hovda MD, Vekhter B, Arora VM, Chung F, Meltzer DO (2013) Sleep-disordered breathing and postoperative outcomes after elective surgery: analysis of the nationwide inpatient sample. Chest 144:903–914

    Article  PubMed  PubMed Central  Google Scholar 

  102. Mori E, Ishikawa M, Kato T, Kazui H, Miyake H, Miyajima M et al (2012) Guidelines for management of idiopathic normal pressure hydrocephalus: second edition. Neurol Med Chir (Tokyo) 52:775–809

    Article  Google Scholar 

  103. Morley JE, Vellas B, Van Kan GA, Anker SD, Bauer JM, Bernabei R et al (2013) Frailty consensus: a call to action. J Am Med Dir Assoc 14:392–397

    Article  PubMed  PubMed Central  Google Scholar 

  104. Mozaffarian D, Benjamin EJ, Go AS, Arnett DK (2015) Executive summary: heart disease and stroke statistics—2015 update a report from the American Heart Association. Circulation 131(4):e29–e322

    Article  PubMed  Google Scholar 

  105. Muluk V, Macpherson DS, Cohn SL, Whinney C (2016) Perioperative medication management. In: Post TW (ed) UpToDate, 5 edn. UpToDate, Waltham, pp 1–50

    Google Scholar 

  106. Naftel RP, Argo JL, Shannon CN, Taylor TH, Tubbs RS, Clements RH et al (2011) Laparoscopic versus open insertion of the peritoneal catheter in ventriculoperitoneal shunt placement: review of 810 consecutive cases. J Neurosurg 115:151–158

    Article  PubMed  Google Scholar 

  107. Nakajima M, Bando K, Miyajima M, Arai H (2009) Lumboperitoneal shunt placement using computed tomography and fluoroscopy in conscious patients. J Neurosurg 111:618–622

    Article  PubMed  Google Scholar 

  108. Nakajima M, Miyajima M, Ogino I, Sugano H, Akiba C, Domon N et al (2015) Use of external lumbar cerebrospinal fluid drainage and lumboperitoneal shunts with Strata NSC valves in idiopathic normal pressure hydrocephalus: a single-center experience. World Neurosurg 83:387–393

    Article  PubMed  Google Scholar 

  109. Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP, Guyton RA et al (2014) 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 63:e57–e185

    Article  PubMed  Google Scholar 

  110. Orandi BJ, Winter JM, Segev DL, Makary MA (2011) Frailty and surgery in the elderly. In: Principles and Practice of Geriatric Surgery. Springer, New York, pp 129–134

    Google Scholar 

  111. Pang D, Grabb PA (1994) Accurate placement of coronal ventricular catheter using stereotactic coordinate-guided free-hand passage. J Neurosurg 80:750–755

    Article  CAS  PubMed  Google Scholar 

  112. Peterson KA, Housden CR, Killikelly C, DeVito EE, Keong NC, Savulich G et al (2016) Apathy, ventriculomegaly and neurocognitive improvement following shunt surgery in normal pressure hydrocephalus. Br J Neurosurg 30(1):38–42

    PubMed  Google Scholar 

  113. Peterson KA, Savulich G, Jackson D, Killikelly C, Pickard JD, Sahakian BJ (2016) The effect of shunt surgery on neuropsychological performance in normal pressure hydrocephalus: a systematic review and meta-analysis. J Neurol 263(8):1669–1677

    Article  PubMed  PubMed Central  Google Scholar 

  114. Pollack IF, Albright AL, Adelson PD (1999) A randomized, controlled study of a programmable shunt valve versus a conventional valve for patients with hydrocephalus. Hakim-Medos Investigator Group. Neurosurgery 45(6):1399–1408

    Article  CAS  PubMed  Google Scholar 

  115. Portnoy HD, Schulte RR, Fox JL, Croissant PD, Tripp L (1973) Anti-siphon and reversible occlusion valves for shunting in hydrocephalus and preventing post-shunt subdural hematomas. J Neurosurg 38:729–738

    Article  CAS  PubMed  Google Scholar 

  116. Pudenz RH (1957) Experimental and clinical observations on the shunting of cerebrospinal fluid into the circulatory system. Clin Neurosurg 5:98–114; discussion 114–115

    Google Scholar 

  117. Pudenz RH, Russell FE, Hurd AH, Shelden CH (1957) Ventriculo-auriculostomy; a technique for shunting cerebrospinal fluid into the right auricle; preliminary report. J Neurosurg 14:171–179

    Article  CAS  PubMed  Google Scholar 

  118. Pujari S, Kharkar S, Metellus P, Shuck J, Williams MA, Rigamonti D (2008) Normal pressure hydrocephalus: long-term outcome after shunt surgery. J Neurol Neurosurg Psychiatr 79:1282–1286

    Article  CAS  PubMed  Google Scholar 

  119. Raftopoulos C, Deleval J, Chaskis C, Leonard A, Cantraine F, Desmyttere F et al (1994) Cognitive recovery in idiopathic normal pressure hydrocephalus: a prospective study. Neurosurgery 35:397–405

    Google Scholar 

  120. Raftopoulos C, Massager N, Balériaux D, Deleval J, Clarysse S, Brotchi J (1996) Prospective analysis by computed tomography and long-term outcome of 23 adult patients with chronic idiopathic hydrocephalus. Neurosurgery 38:51–59

    Article  CAS  PubMed  Google Scholar 

  121. Raysi Dehcordi S, De Tommasi C, Ricci A, Marzi S, Ruscitti C, Amicucci G et al (2011) Laparoscopy-assisted ventriculoperitoneal shunt surgery: personal experience and review of the literature. Neurosurg Rev 34:363–371

    Article  PubMed  Google Scholar 

  122. Razay G, Vreugdenhil A, Liddell J (2009) A prospective study of ventriculo-peritoneal shunting for idiopathic normal pressure hydrocephalus. J Clin Neurosci 16:1180–1183

    Article  PubMed  Google Scholar 

  123. Reinprecht A, Czech T, Dietrich W (1995) Clinical experience with a new pressure-adjustable shunt valve. Acta Neurochir (Wien) 134:119–124

    Article  CAS  Google Scholar 

  124. Relkin N, Marmarou A, Klinge P, Bergsneider M, Black PM (2005) Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery 57:S4–S16

    Google Scholar 

  125. Riva-Cambrin J, Kestle JRW, Holubkov R, Butler J, Kulkarni AV, Drake J et al (2016) Risk factors for shunt malfunction in pediatric hydrocephalus: a multicenter prospective cohort study. J Neurosurg Pediatr 17(4):382–390

    Article  PubMed  Google Scholar 

  126. Robert-Ebadi H, Le Gal G, Righini M (2009) Use of anticoagulants in elderly patients: practical recommendations. Clin Interv Aging 4:165–177

    CAS  PubMed  PubMed Central  Google Scholar 

  127. Robinson S (2016) Editorial: reducing the risk of shunt malfunction: beacons of light. J Neurosurg Pediatr 17(4):379–381

    Article  PubMed  Google Scholar 

  128. Rockwood K, Mitnitski A (2007) Frailty in relation to the accumulation of deficits. J Gerontol A Biol Sci Med Sci 62:722–727

    Article  PubMed  Google Scholar 

  129. Roth JS, Park AE, Gewirtz R (2000) Minilaparoscopically assisted placement of ventriculoperitoneal shunts. Surg Endosc 14:461–463

    Article  CAS  PubMed  Google Scholar 

  130. Roth J, Sagie B, Szold A, Elran H (2007) Laparoscopic versus non-laparoscopic-assisted ventriculoperitoneal shunt placement in adults. A retrospective analysis. Surg Neurol 68:177–184

    Google Scholar 

  131. Sæhle T, Farahmand D, Eide PK, Tisell M, Wikkelsø C (2014) A randomized controlled dual-center trial on shunt complications in idiopathic normal-pressure hydrocephalus treated with gradually reduced or “fixed” pressure valve settings. J Neurosurg 121:1257–1263

    Article  PubMed  Google Scholar 

  132. Sankey EW, Jusué-Torres I, Elder BD, Goodwin CR, Batra S, Hoffberger J et al (2015) Functional gait outcomes for idiopathic normal pressure hydrocephalus after primary endoscopic third ventriculostomy. J Clin Neurosci 22:1303–1308

    Article  PubMed  Google Scholar 

  133. Sato K, Shimizu S, Oka H, Fujii K (2013) Intraoperative fluoroscopy with contrast medium for correct lumbar catheter placement in lumboperitoneal shunts. Kitasato Med J 43:155–158

    Google Scholar 

  134. Schubert F, Fijen BP, Krauss JK (2005) Laparoscopically assisted peritoneal shunt insertion in hydrocephalus: a prospective controlled study. Surg Endosc 19:1588–1591

    Article  CAS  PubMed  Google Scholar 

  135. Schucht P, Banz V, Trochsler M, Iff S, Krähenbühl AK, Reinert M et al (2015) Laparoscopically assisted ventriculoperitoneal shunt placement: a prospective randomized controlled trial. J Neurosurg 122:1058–1067

    Article  PubMed  Google Scholar 

  136. Seldinger SI (1953) Catheter replacement of the needle in percutaneous arteriography: a new technique. Acta Radiol 39:368–376

    Article  CAS  PubMed  Google Scholar 

  137. Shaw R, Everingham E, Mahant N, Jacobson E, Owler B (2016) Clinical outcomes in the surgical treatment of idiopathic normal pressure hydrocephalus. J Clin Neurosci 29:81–86

    Article  PubMed  Google Scholar 

  138. Shaw R, Mahant N, Jacobson E, Owler B (2016) A review of clinical outcomes for gait and other variables in the surgical treatment of idiopathic normal pressure hydrocephalus. Mov Disord Clin Pract. doi:10.1002/mdc3.12335

    Google Scholar 

  139. Simon TD, Butler J, Whitlock KB, Browd SR, Holubkov R, Kestle JR, Kulkarni AV, Langley M, Limbrick DD Jr, Mayer-Hamblett N, Tamber M, Wellons JC 3rd, Whitehead WE, Riva-Cambrin J, Hydrocephalus Clinical Research Network (2014) Risk factors for first cerebrospinal fluid shunt infection: findings from a multi-center Prospective Cohort Study. J Pediatr 164:1462–1468.e2

    Article  PubMed  PubMed Central  Google Scholar 

  140. Singh M, Liao P, Kobah S, Wijeysundera DN, Shapiro C, Chung F (2013) Proportion of surgical patients with undiagnosed obstructive sleep apnoea. Br J Anaesth 110:629–636

    Article  CAS  PubMed  Google Scholar 

  141. Singh K, Raj J, Tiwari DP (2013) Conventional versus neuro-navigation guided shunt surgery. World J Med Res 2:6

    Google Scholar 

  142. Smetana GW, Lawrence VA, Cornell JE (2006) Preoperative pulmonary risk stratification for noncardiothoracic surgery: systematic review for the American College of Physicians. Ann Intern Med 144:581–595

    Article  PubMed  Google Scholar 

  143. Spyropoulos DAC, Merli G (2006) Management of venous thromboembolism in the elderly. Drugs Aging 23:651–671

    Article  CAS  PubMed  Google Scholar 

  144. Svoboda SM, Park H, Naff N, Dorai Z, Williams MA, Youssef Y (2015) Preventing distal catheter obstruction in laparoscopic ventriculoperitoneal shunt placement in adults: The “Falciform Technique”. J Laparoendoscopic Adv Surg Tech 25(8):642–645

    Google Scholar 

  145. Tasiou A, Brotis AG, Esposito F, Paterakis KN (2016) Endoscopic third ventriculostomy in the treatment of idiopathic normal pressure hydrocephalus: a review study. Neurosurg Rev 39(4):557–563

    Google Scholar 

  146. Thomas GA, Farrow RC, Liu S (2012) No clog shunt using a compact fluid drag path

    Google Scholar 

  147. Toma AK, Papadopoulos MC, Stapleton S, Kitchen ND, Watkins LD (2013) Systematic review of the outcome of shunt surgery in idiopathic normal-pressure hydrocephalus. Acta Neurochir (Wien) 155:1977–1980

    Article  Google Scholar 

  148. Toma AK, Stapleton S, Papadopoulos MC, Kitchen ND, Watkins LD (2011) Natural history of idiopathic normal-pressure hydrocephalus. Neurosurg Rev 34:433–439

    Article  PubMed  Google Scholar 

  149. Tudor KI, Tudor M, McCleery J, Car J (2015) Endoscopic third ventriculostomy (ETV) for idiopathic normal pressure hydrocephalus (iNPH). Cochrane Database Syst Rev (7):CD010033

    Google Scholar 

  150. Turner RD, Rosenblatt SM, Chand B, Luciano MG (2007) Laparoscopic peritoneal catheter placement: results of a new method in 111 patients. Neurosurgery 61:167–174

    Google Scholar 

  151. Wells DL, Allen JM (2013) Ventriculoperitoneal shunt infections in adult patients. AACN Adv Crit Care 24:6–12

    Article  PubMed  Google Scholar 

  152. Williams MA, Malm J (2016) Diagnosis and treatment of idiopathic normal pressure hydrocephalus. Continuum Lifelong Learning Neurol 22:577–579

    Google Scholar 

  153. Williams MA, Relkin NR (2013) Diagnosis and management of idiopathic normal-pressure hydrocephalus. Neurol Clini Pract 3:375–385

    Article  Google Scholar 

  154. Wozniak SE, Coleman J, Katlic MR (2015) Optimal preoperative evaluation and perioperative care of the geriatric patient: a surgeon’s perspective. Anesthesiol Clin 33:481–489

    Article  PubMed  Google Scholar 

  155. Zarraga IGE, Kron J (2013) Oral anticoagulation in elderly adults with atrial fibrillation: integrating new options with old concepts. J Am Geriatr Soc 61:143–150

    Article  PubMed  Google Scholar 

  156. Zemack G, Romner B (2000) Seven years of clinical experience with the programmable Codman Hakim valve: a retrospective study of 583 patients. J Neurosurg 92:941–948

    Article  CAS  PubMed  Google Scholar 

  157. Zemack G, Romner B (2002) Adjustable valves in normal-pressure hydrocephalus: a retrospective study of 218 patients. Neurosurgery 51:1392–1402

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Division of Neurosurgery, Department of Clinical Neuroscience, University of Calgary, Calgary, AB, Canada

    Albert M. Isaacs BSc, MD & Mark G. Hamilton MD, CM FRCSC, FAANS

  2. Adult and Transitional Hydrocephalus and CSF Disorders, University of Washington School of Medicine, Seattle, WA, USA

    Michael A. Williams MD, FAAN

  3. Adult Hydrocephalus Program, Department of Clinical Neuroscience, University of Calgary, Calgary, AB, Canada

    Mark G. Hamilton MD, CM FRCSC, FAANS

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  1. Albert M. Isaacs BSc, MD
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  2. Michael A. Williams MD, FAAN
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  3. Mark G. Hamilton MD, CM FRCSC, FAANS
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Correspondence to Michael A. Williams MD, FAAN .

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  1. Department of Neurosurgery, University Hospital of Lyon, Lyon, France

    Moncef Berhouma

  2. Hôpital des Charpennes, Hospices civils de Lyon, Villeurbanne, France

    Pierre Krolak-Salmon

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Isaacs, A.M., Williams, M.A., Hamilton, M.G. (2017). Hydrocephalus in the Elderly: Surgical Management of Idiopathic Normal Pressure Hydrocephalus. In: Berhouma, M., Krolak-Salmon, P. (eds) Brain and Spine Surgery in the Elderly. Springer, Cham. https://doi.org/10.1007/978-3-319-40232-1_26

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