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Overall Safety of Peroxides

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Tooth Whitening

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Abstract

Current tooth whiteners contain peroxides as active ingredients, which release hydrogen peroxide (H2O2) in the process of application. The primary source of safety concerns with the peroxide-based tooth whiteners is the capability of H2O2 to produce oxidative free radicals or reactive oxygen species (ROS), which have been associated with various pathological consequences including carcinogenesis and degenerative diseases. This chapter will review and discuss toxicology of H2O2, its presence in the human body, and its potential systemic effects, genotoxicity, and carcinogenicity on the basis of evidence available in the literature.

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Authors and Affiliations

  1. Center for Dental Research, Loma Linda University School of Dentistry, 11175 Campus Street, Loma Linda, CA, 92350, USA

    Yiming Li DDS, MSD, PhD

  2. Microbiology and Molecular Genetics, Loma Linda University School of Dentistry, Loma Linda, CA, USA

    Yiming Li DDS, MSD, PhD

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  1. Yiming Li DDS, MSD, PhD
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Correspondence to Yiming Li DDS, MSD, PhD .

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  1. University of Minnesota, MINNEAPOLIS, USA

    Jorge Perdigão

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Li, Y. (2016). Overall Safety of Peroxides. In: Perdigão, J. (eds) Tooth Whitening. Springer, Cham. https://doi.org/10.1007/978-3-319-38849-6_3

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  • DOI: https://doi.org/10.1007/978-3-319-38849-6_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-38847-2

  • Online ISBN: 978-3-319-38849-6

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