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Hepatitis

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Dermatology in Public Health Environments

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Abstract

The World Health Organization estimates that more than 400 million people are infected with either hepatitis B virus or hepatitis C virus while approximately 150 million have chronic hepatitis C. Viral hepatitis, specifically hepatitis B and hepatitis C, not only causes liver disease but also can present with extrahepatic manifestations, including cutaneous lesions. Among all extrahepatic manifestations of liver diseases, cutaneous manifestations are the most common. In addition, they are easily recognizable and may provide the first clues of liver disease. Serum sickness and polyarteritis nodosa are the main cutaneous manifestations related to hepatitis B virus infection. Cutaneous manifestations related to hepatitis C virus infection include mixed cryoglobulinemia, porphyria cutanea tarda, and lichen planus. In addition, the appearance of adverse cutaneous reactions both local and diffuse is frequent during the treatment of hepatitis C virus infection.

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Author information

Authors and Affiliations

  1. Mãe de Deus, Dermatology, Porto Alegre, Brazil

    Gislaine Silveira Olm MD, MSc

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  1. Gislaine Silveira Olm MD, MSc
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Correspondence to Gislaine Silveira Olm MD, MSc .

Editor information

Editors and Affiliations

  1. Dermatology Service of Clinical, Hospital of Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil

    Renan Rangel Bonamigo

  2. Health Secretary of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

    Sergio Ivan Torres Dornelles

Glossary

Cryoglobulinemia 

Characterized by the presence of cryoglobulins in the serum. This may result in a clinical syndrome of systemic inflammation caused by cryoglobulin-containing immune complexes.

Jaundice 

Yellowish discoloration of the skin, white of the eyes, and mucous membranes caused by deposition of bile salts in the tissues.

Hepatitis 

Inflammation of the liver, caused by a virus or a toxin and characterized by jaundice, liver enlargement, and fever.

Polyarteritis nodosa 

Systemic necrotizing vasculitis that predominantly affects medium-sized muscular arteries and often involves small muscular arteries, resulting in secondary tissue ischemia.

Porphyria 

Group of diseases in which there is abnormal metabolism of the blood pigment hemoglobin.

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Olm, G.S. (2018). Hepatitis. In: Bonamigo, R., Dornelles, S. (eds) Dermatology in Public Health Environments. Springer, Cham. https://doi.org/10.1007/978-3-319-33919-1_40

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  • DOI: https://doi.org/10.1007/978-3-319-33919-1_40

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  • Online ISBN: 978-3-319-33919-1

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