Abstract
There is an urgent need for the effective treatment of individuals suffering from spinal cord injury (SCI). Advances in the understanding of stem cells have expanded pharmacotherapy to stem cell therapy for SCI. This chapter summarizes pathophysiology of SCI, pharmacological and stem cell therapy in SCI and proposes six-point cyclical schema for effective clinical translation of neural stem cell therapy for SCI. SCI is a complex condition; the numerous pathophysiological mechanisms occurring at varying phases of SCI suggests that a single approach to the treatment of SCI may not be optimal. As the field continues to mature, the hope is that the knowledge gained from laboratory studies will be translated into the development of an effective multi-pronged treatment strategy for SCI.
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S. Tu was a recipient of National Health and Medical Research Council postgraduate scholarship.
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Tu, S., Tu, J. (2017). Stem Cell Therapy for Spinal Cord Injury. In: Pham, P. (eds) Neurological Regeneration. Stem Cells in Clinical Applications. Springer, Cham. https://doi.org/10.1007/978-3-319-33720-3_8
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