Definition
The most common nonneoplastic cysts are functional ovarian cysts, i.e., follicular cysts and corpus luteum cysts, which are developed as a result of disturbed ovulation. Follicular cyst results when the dominant follicle fails to release an oocyte and continues to grow or when immature follicle fails to involute. Usually, these cysts produce no symptoms and disappear by themselves within a few months.
Follicular Cyst
Synonyms
Follicle cyst; Follicular cyst
Cytologic Findings
Fluid Aspiration (FNA)Macroscopically fluid is clear, yellowish, rarely haemorrhagic (Ivić et al. 1976). Microscopically cellular composition from follicular cysts aspirations is diverse, ranging from scanty to abundantly cellular (Greenebaum et al. 1992). The background is finely granular, rich in fibrin.
Two granulosa cell types predominate, depending of follicle stage development (Greenebaum et al. 1992). The first type is a small cell, approximately the size of histiocytes, round or oval in shape,...
References and Further Reading
Allias, F., Chanoz, J., Blache, G., et al. (2000). Value of ultrasound-guided fine-needle aspiration in the management of ovarian and paraovarian cysts. Diagnostic Cytopathology, 22(2), 70–80.
Bibbo, M., Wood, M., & Fitzpatrick, B. (2008). Peritoneal washings and ovary. In M. Bibbo & D. Wilbur (Eds.), Comprehensive cytopathology (3rd ed., p. 294). Amsterdam: Saunders Elsevier.
Ganjei, P. (1995). Fine-needle aspiration cytology of ovary. Clinics in Laboratory Medicine, 15, 705–726.
Greenebaum, E., Mayer, J., Stangel, J., & Hughes, P. (1992). Aspiration cytology of ovarian cysts in in vitro fertilization patients. Acta Cytologica, 36, 11–18.
Ivić, J., Krznar, B., & Audy, S. (1976). Intraoperative cytodiagnosis of ovarian tumors. Jugoslavenska Ginekologija i Opstetricija, 16(2), 81–90.
Manek, S., & Mahovlić, V. (2010). Ovaries, fallopian tubes and associated lesions. In W. Gray & G. Kocjan (Eds.), Diagnostic cytopathology (3rd ed., pp. 721–735). Oxford: Elsevier.
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Jurič, D., Mahovlić, V. (2017). Ovarian Nonneoplastic Cysts, Cytological Findings. In: Schmitt, F. (eds) Cytopathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-33286-4_946
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