Abstract
The eponym for Dupuytren disease was coined because Dupuytren, a French surgeon, performed a surgery using an open transverse incision in 1831 on his patient with a hand contracture. However, Dupuytren disease was actually originally described earlier in 1614 by Felix Plater of Basel. Some reports describe Dupuytren disease even earlier in Orkney and Iceland in the twelfth and thirteenth centuries. Interestingly, Englishman John Hunter reported that Dupuytren disease originated in ligaments and not tendons, in 1777—the year of Dupuytren’s birth. Hunter also suggested that surgical fasciotomy might be done to resolve the contractures (Elliot 1989). The introduction of collagenase for the treatment of Dupuytren disease is a much more recent event. Doctors Hurst and Badalamente invented this therapeutic option for treating Dupuytren disease with collagenase and have championed its development since the early 1990s (Hurst 2011).
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Conflict of Interest Statement
Lawrence C. Hurst and Marie Badalamente of Partial Xiaflex/Xiapex royalty from BioSpecifics Technologies Corp. Marie Relevo and Kerri Kulovitz have nothing to declare.
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Hurst, L.C., Badalamente, M.A., Kulovitz, K., Relevo, M. (2017). Collagenase Injection: Journey from Bench to Current Advanced Clinical Use. In: Werker, P., Dias, J., Eaton, C., Reichert, B., Wach, W. (eds) Dupuytren Disease and Related Diseases - The Cutting Edge. Springer, Cham. https://doi.org/10.1007/978-3-319-32199-8_14
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DOI: https://doi.org/10.1007/978-3-319-32199-8_14
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