Abstract
This chapter discusses the most up-to-date and comprehensive approach to the child with neuropathic bladder dysfunction, from the moment the fetus is identified until the adolescent years, in order to gain first-hand knowledge of management. It describes the controversies that still exist and the reasons why the author has chosen his path of care. It tries to explain the physiology involved so the reader can appreciate the therapeutic options chosen by the author. Once the chapter is thoroughly analyzed, the reader should have the ability to decide his/her own style of management for these children based on solid foundation of information.
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Abbreviations
- CIC:
-
Clean intermittent catheterization
- DSD:
-
Dyssynergy
- UTI:
-
Urinary tract infection
- VUR:
-
Vesicoureteral reflux
References
Adzick NS, Thom EA, Spong CY, Brock III JW, Burrows PK, Johnson MP, et al. A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med. 2011;364:993–1004.
Koh CJ, DeFilippo RE, Borer JG, Khoshbin S, Bauer SB. Bladder and external urethral sphincter function after prenatal closure of myelomeningocele. J Urol. 2006;176:2232–6.
Lee NG, Gomez P, Uberoi V, Kokorowski PJ, Khoshbin S, Bauer SB, et al. In utero closure of myelomeningocele does not improve lower urinary tract function. J Urol. 2012;188:1567–71.
Kroovand RL, Bell W, Hart LJ, Benfeld KY. The effect of back closure on detrusor function in neonates with myelodysplasia. J Urol. 1990;144:423–5.
Chiaramonte RM, Horowitz EM, Kaplan GA, Brock WA. Implications of hydronephrosis in newborns with myelodysplasia. J Urol. 1986;136:427–9.
Bauer SB, Labib KB, Dieppa RA, Retik AB. Urodynamic evaluation in a boy with myelodysplasia and incontinence. Urology. 1977;10:354–62.
Bauer SB, Austin PF, Rawashdeh YF, de Jong TP, Franco I, Siggard C, et al. International Children’s Continence Society’s recommendations for initial diagnostic evaluation and follow-up in congenital neuropathic bladder and bowel dysfunction in children. Neurourol Urodyn. 2012;31:610–4.
Frimberger D, Cheng E, Kropp BP. The current management of the neurogenic bladder in children with spina bifida. Pediatr Clin North Am. 2012;59:757–67.
Joseph DB. The effect of medium-fill and slow-fill cystometry on bladder pressure in infants and children with myelodysplasia. J Urol. 1992;147:444–6.
Blaivas JG, Labib KB, Bauer SB, Retik AB. A new approach to elec-tromyography of the external urethral sphincter. J Urol. 1977;117:773–7.
McGuire EJ, Woodside JR, Borden TA, Weiss RM. The prognostic value of urodynamic testing in myelodysplastic patients. J Urol. 1981;126:205–9.
Bauer SB, Hallet M, Khoshbin S, Lebowitz RL, Winston KR, Gibson S, et al. The predictive value of urodynamic evaluation in the newborn with myelodysplasia. JAMA. 1984;152:650–2.
Sidi AA, Dykstra DD, Gonzalez R. The value of urodynamic testing in the management of neonates with myelodysplasia: a prospective study. J Urol. 1986;135:90–3.
Perez LM, Khoury J, Webster GD. The value of urodynamic studies in infants less than one year old with congenital spinal dysraphism. J Urol. 1992;148:584–7.
Teichman JMH, Scherz HC, Kim KD, Cho DH, Packer MG, Kaplan GW. An alternative approach to myelodysplasia management: aggressive observation and prompt intervention. J Urol. 1994;152:807–11.
Hopps CV, Kropp KA. Preservation of renal function in children with myelomeningocele managed with basic newborn evaluation and close followup. J Urol. 2003;169:305–8.
Snodgrass WT, Gargollo PC. Urologic care of the neurogenic bladder in children. Urol Clin North Am. 2010;37:207–14.
Bauer SB. Myelodysplasia: newborn evaluation and management. In: McLaurin RL, editor. Spina bifida: a multidisciplinary approach. New York: Praeger; 1984. p. 262–7.
Kopp C, Greenfield SP. Effects of neurogenic bladder dysfunction in utero seen in neonates with myelodysplasia. Br J Urol. 1993;71:739–42.
Wu H-Y, Baskin LS, Kogan BA. Neurogenic bladder dysfunction due to myelomeningocele: neonatal versus childhood treatment. J Urol. 1997;157:2295–7.
Kurzrock EA, Polse S. Renal deterioration in myelodysplastic children: urodynamic evaluation and clinical correlates. J Urol. 1998;159:1657–61.
Klose AG, Sackett CK, Mesrobian H-GJ. Management of children with myelodysplasia. Urologic alternatives. J Urol. 1990;144:1446–9.
Tanaka H, Kakizaki H, Kobayashi S, Shibata T, Ameda K, Koyanagi T, et al. The relevance of urethral resistance in children with myelodysplasia: its impact on upper urinary tract deterioration and the outcome of conservative management. J Urol. 1999;161:929–32.
Joseph DB, Bauer SB, Colodny AH, Mandell J, Retik AB. Clean intermittent catheterization in infants with neurogenic bladder. Pediatrics. 1989;84:78–83.
Kari JA, Safdar O, Jamjoom R, Anshasi W. Renal involvement in children with spina bifida. Saudi J Kidney Dis Transpl. 2009;20:102–5.
Kaefer M, Pabby A, Kelly M, Darbey M, Bauer SB, et al. Improved bladder function after prophylactic treatment of the high risk neurogenic bladder in newborns with myelomeningocele. J Urol. 1999;162:1068–71.
Bauer SB. Early evaluation and management of children with spina bifida. In: King LR, editor. Urologic surgery in neonates and young infants. Philadelphia: WB Saunders; 1988. p. 252–64.
Austin PF, Bauer SB, Bower W, Chase J, Franco I, Hoebeke P, et al. The standardization of terminology of lower urinary tract function in children and adolescents: update report from the Standardization Committee of the International Children’s Continence Society. J Urol. 2014;191:1863–5.
Bauer SB. Neuropathic dysfunction of the lower urinary tract. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, editors. Campbell-walsh urology. 9th ed. Philadelphia: Saunders Elsevier; 2006. p. 3625–55.
van Gool JD, Dik P, de Jong TP. Bladder-sphincter dysfunction in myelomeningocele. Eur J Pediatr. 2001;160:414–20.
Bauer SB. The management of spina bifida from birth onwards. In: Whitaker RH, Woodard JR, editors. Paediatric urology. London: Butterworths; 1985. p. 87–112.
Edelstein RA, Bauer SB, Kelly MD, Darbey MM, Peters CA, Atala A, et al. The long-term urologic response of neonates with myelodysplasia treated proactively with intermittent catheterization and anticholinergic therapy. J Urol. 1995;154:1500–4.
Dik P, van Gool JD, de Jong-de Vos van Steenwijk CC, de Jong TP. Early start therapy preserves kidney function in spina bifida patients. Eur Urol. 2006;49:908–13.
Seki N, Masuda K, Kinukawa N, Senoh K, Naito S. Risk factors for febrile urinary tract infection in children with myelodysplasia treated by clean intermittent catheterization. Int J Urol. 2004;11:973–7.
Van Gool JD, Juijten RH, Donckerwolcke RA, Kramer PP. Detrusor- sphincter dyssynergia in children with myelomeningocele: a prospective study. Z Kinderchir. 1982;37:148–51.
Stoneking BJ, Brock JW, Pope JC, Adams MC. Early evolution of bladder emptying after myelomeningocele closure. Urology. 2001;58:767–71.
Ghoniem GM, Roach MB, Lewis VH, Harmon EP. The value of leak point pressure and bladder compliance in the urodynamic evaluation of myelomeningocele patients. J Urol. 1990;144:1440–2.
Geranoitis E, Koff SA, Enrile B. Prophylactic use of clean intermittent catheterization in treatment of infants and young children with myelomeningocele and neurogenic bladder dysfunction. J Urol. 1988;139:85–6.
Landau EH, Churchill BM, Jayanthi VR, Gilmour RF, Steckler RE, McLorie GA, et al. The sensitivity of pressure specific bladder volume versus total bladder capacity as a measure of bladder storage dysfunction. J Urol. 1994;152:1578–81.
Kasabian NG, Bauer SB, Dyro FM, Colodny AH, Mandell J, Retik AB. The prophylactic value of clean intermittent catheterization and anticholinergic medication in newborns and infants with myelodysplasia at risk of developing urinary tract deterioration. Am J Dis Child. 1992;146:840–3.
Barbalais GA, Klauber GT, Blaivas JG. Critical evaluation of the Credé maneuver: a urodynamic study of 207 patients. J Urol. 1983;130:720–8.
Flood HD, Ritchey ML, Bloom DA, Huang C, McGuire EJ. Outcome of reflux in children with myelodysplasia managed by bladder pressure monitoring. J Urol. 1994;152:1574–7.
Stein DR, Gordon CM, Feldman HA, Hobbs NM, Bauer SB, Baum MB. Chronic kidney disease in children with myelodysplasia/spina bifida. Poster presentation, Pediatric Academic Societies; 2011. (Abstract # 752298).
Agarwal SK, McLorie GA, Grewal D, Joyner BD, Bägli DJ, Khoury AE, et al. Urodynamic correlates of resolution of reflux meningomyelocele patients. J Urol. 1997;158:580–2.
Bauer SB, Colodny AH, Retik AB. The management of vesico-ureteral reflux in children with myelodysplasia. J Urol. 1982;128:102–5.
Kaplan WE, Firlit CF. Management of reflux in myelodysplastic children. J Urol. 1983;129:1195–7.
Jeffs RD, Jones P, Schillinger JF. Surgical correction of vesico-ureteral reflux in children with neurogenic bladder. J Urol. 1976;115:449–55.
Kass EJ, Koff SA, Lapides J. Fate of vesico-ureteral reflux in children with neuropathic bladders managed by intermittent catheterization. J Urol. 1981;125:63–4.
Schlussel R. Cystoscopic correction of reflux. Curr Urol Rep. 2004;5:127–31.
Elder JS, Diaz M, Caldamone AA, Cendron M, Greenfield S, Hurwitz R. Endoscopic therapy for vesicoureteral reflux: meta-analysis. I. Reflux resolution and urinary tract infection. J Urol. 2006;175:716–22.
Duckett JW. Cutaneous vesicostomy in childhood. Urol Clin North Am. 1974;1:485–95.
Mandell J, Bauer SB, Colodny AH, Retik AB. Cutaneous vesicostomy in infancy. J Urol. 1981;126:92–3.
Morrisroe SN, O’Connor RC, Nanigian DK, Kurzrock EA, Stone AR. Vesicostomy revisited: the best treatment for the hostile bladder in myelodysplastic children? BJU Int. 2005;96:397–400.
Spindel MR, Bauer SB, Dyro FM, Krarup C, Khoshbin S, Winston KR, et al. The changing neuro-urologic lesion in myelodysplasia. JAMA. 1987;258:1630–3.
Lais A, Kasabian NG, Dyro FM, Scott RM, Kelly MD, Bauer SB. Neurosurgical implications of continuous neuro-urological surveillance of children with myelodysplasia. J Urol. 1993;150:1879–83.
Dator DP, Hatchett L, Dyro EM, Shefner JM, Bauer SB. Urodynamic dysfunction in walking myelodysplastic children. J Urol. 1992;148:362–5.
Pontari MA, Keating M, Kelly MD, Dyro F, Bauer SB. Retained sacral function in children with high level myelodysplasia. J Urol. 1995;154:775–7.
Tarcan T, Bauer S, Olmedo E, Koshbin S, Kelly M, Darbey M. Long-term follow-up of newborns with myelodysplasia and normal urodynamic findings: is it necessary? J Urol. 2001;165:564–7.
Mandell J, Lebowitz RL, Hallett M, Khoshbin S, Bauer SB. Urethral narrowing in region of external sphincter: radiologic urodynamic correlations in boys with myelodysplasia. Am J Roentgenol. 1980;134:731–5.
Bauer SB. The value of needle EMG in open and occult spinal dysraphisms. Vanderbilt Children’s Hospital Lecture. Accessed 6 Mar 2015.
Bauer SB. The management of the myelodysplastic child: a paradigm shift. BJU Int. 2003;92:23–8.
Rawashdeh YF, Austin P, Siggaard C, Bauer SB, Franco I, de Jong TP, et al. International Children’s Continence Society’s recommendations for therapeutic intervention in congenital neuropathic bladder and bowel dysfunction in children. Neurourol Urodyn. 2012;31:615–20.
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Bauer, S.B. (2016). Congenital Neuropathic Bladder. In: Barakat, A., Rushton, H. (eds) Congenital Anomalies of the Kidney and Urinary Tract. Springer, Cham. https://doi.org/10.1007/978-3-319-29219-9_11
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DOI: https://doi.org/10.1007/978-3-319-29219-9_11
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