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Risk and Epidemiology of Infections After Solid Organ Transplantation

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Transplant Infections

Abstract

Transplant recipients are uniquely susceptible to infectious diseases due to the nature of their underlying conditions and their immunosuppressed status; consequently infections in solid organ transplantation may be associated with significant morbidity and mortality. These patients are not only vulnerable to a broad range of infectious organisms including those not normally considered to be pathogenic, but also prone to unusual presentations and more severe manifestations of infection. Chapter 7 is an introduction to the risks and epidemiology of infections in solid organ transplantation. It provides an overview of pre-transplantation donor and candidate screening, reviews the classic timeline for infection, and discusses methods for disease prevention including immunizations, environmental control, and post-transplantation prophylaxis.

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Authors and Affiliations

  1. Department of Infectious Diseases, Abington-Jefferson Health, 1235 Old York Rd Suite 220, Abington, PA, 19001, USA

    Ingi Lee M.D., M.S.C.E.

  2. Department of Medicine, Hospital of the University of Pennsylvania, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce Street, Ste E, 3 Silverstein, Philadelphia, PA, 19104, USA

    Emily A. Blumberg M.D.

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  1. Ingi Lee M.D., M.S.C.E.
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Correspondence to Emily A. Blumberg M.D. .

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Editors and Affiliations

  1. Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

    Per Ljungman

  2. Tufts University School of Medicine Tufts Medical Center, Boston, MA, USA

    David Snydman

  3. University of Washington Fred Hutchinson Cancer Research Center, Seattle, WA, USA

    Michael Boeckh

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Lee, I., Blumberg, E.A. (2016). Risk and Epidemiology of Infections After Solid Organ Transplantation. In: Ljungman, P., Snydman, D., Boeckh, M. (eds) Transplant Infections. Springer, Cham. https://doi.org/10.1007/978-3-319-28797-3_7

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  • DOI: https://doi.org/10.1007/978-3-319-28797-3_7

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