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Deep Brain Stimulation for Parkinson Disease

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Abstract

Deep brain stimulation (DBS) therapy is now considered one of the most important advances in the treatment of Parkinson disease (PD), a progressive neurodegenerative disorder. DBS improves the cardinal motor symptoms of PD (rest tremor, bradykinesia, rigidity), markedly reduces motor complications (dyskinesias and wearing off), and dramatically improves quality of life. In this chapter, we review how DBS came to be and present the current science behind how DBS works. Clinical indications and up-to-date evidence on clinical outcomes of DBS are presented. Finally, the risks and side effects of DBS, and advances in DBS technology are discussed.

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Authors and Affiliations

  1. University of Michigan Medical School, 2301 Commonwealth Blvd., Michigan House Room 1032B, Ann Arbor, MI, 48105-2945, USA

    Kelvin L. Chou MD

  2. University of Michigan Health Systems/VA Ann Arbor Healthcare System, Department of Neurosurgery, Ann Arbor, MI, USA

    Emily L. Levin MD & Daniel Leventhal MD, PhD

  3. University of Michigan, Department of Neurosurgery, Ann Arbor, MI, USA

    Parag G. Patil MD, PhD

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  1. Sheffield Institute for Translational Neuroscience, Department of Neuroscience, Faculty of Medicine, Dentistry & Health, University of Sheffield, Sheffield, South Yorkshire, United Kingdom

    Arshad Majid

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Chou, K.L., Levin, E.L., Patil, P.G., Leventhal, D. (2017). Deep Brain Stimulation for Parkinson Disease. In: Majid, A. (eds) Electroceuticals. Springer, Cham. https://doi.org/10.1007/978-3-319-28612-9_5

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