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Mathematical Modelling of Radiobiological Parameters

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Radiobiology of Glioblastoma

Part of the book series: Current Clinical Pathology ((CCPATH))

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Abstract

All treatment strategies are studied at the preclinical and clinical level, and the related endpoints are used to extract radiobiological parameters in mathematical models. This chapter aims to provide an overview of these approaches based on clinical and cellular data.

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Author information

Authors and Affiliations

  1. I.R.C.C.S. Regional Cancer Hospital C.R.O.B., Rionero-in-Vulture, PZ, Italy

    Piernicola Pedicini

  2. Laboratory of medical physics and expert systems, Regina Elena National Cancer Institute, via E. Chianesi 53, Rome, 00144, Italy

    Lidia Strigari

  3. Physics Department, Spedali Civili Hospital, Brescia, Italy

    Luigi Spiazzi

  4. Sacro Cuore Don Calabria Hospital, Negrar-Verona, Italy

    Alba Fiorentino

  5. Tuscany Tumor Institute, Florence, Italy

    Paolo Tini & Luigi Pirtoli

  6. Unit of Radiation Oncology, University Hospital of Siena (Azienda Ospedaliera-Universitaria Senese), Viale Bracci 11, Siena, 53100, Italy

    Paolo Tini

  7. Unit of Radiation Oncology, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy

    Luigi Pirtoli

Authors
  1. Piernicola Pedicini
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  2. Lidia Strigari
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  3. Luigi Spiazzi
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  4. Alba Fiorentino
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  5. Paolo Tini
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  6. Luigi Pirtoli
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Corresponding author

Correspondence to Lidia Strigari .

Editor information

Editors and Affiliations

  1. University of Siena, Sec. of Radiation Oncology,Dept. of Med., Siena, Italy

    Luigi Pirtoli

  2. Dept. of Applied Clinical & Biotech Sci., University of L’Aquila, L’Aquila, Italy

    Giovanni Luca Gravina

  3. Department of Biology, Temple University, Philadelphia, Pennsylvania, USA

    Antonio Giordano

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Pedicini, P., Strigari, L., Spiazzi, L., Fiorentino, A., Tini, P., Pirtoli, L. (2016). Mathematical Modelling of Radiobiological Parameters. In: Pirtoli, L., Gravina, G., Giordano, A. (eds) Radiobiology of Glioblastoma. Current Clinical Pathology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-28305-0_6

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