Abstract
Recent breast tissue dielectric spectroscopy measurements in [35] suggest that the malignant-to-benign dielectric contrast may not be sufficiently high to allow for tumour classification based on backscatter intensity. Alternatively, it is well known that the architectural distortion in breast parenchyma can aid in distinguishing malignant tumours from benign masses [56, 65]. Mammographic image analysis shows that malignant tumours usually have an irregular shape and are surrounded by a radiating pattern of linear spicules, also their margins are obscured and indistinct. Conversely, benign tumours are roughly elliptical and usually have well-circumscribed margins [56, 65]. Accordingly, microwave backscatter signature—the signal which is reflected when a target is illuminated by microwaves—could be potentially useful for discrimination between benign and malignant tumours, and for inferring their size. Tomographic image reconstruction methods, which solve the inverse scattering problem to obtain a coarse estimation of the breast dielectric profile, have been used in this context [19].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Bartholomew DJ, Steele F, Moustaki I, Galbraith JI (2002) The analysis and interpretation of multivariate data for social scientists. CRC Press, Florida, USA
Bennett KP, Campbell C (2000) Support vector machines: hype or hallelujah? ACM SIGKDD Explorations Newsletter 2(2):1–13
Bond EJ, Li X, Hagness SC, Van Veen BD (2003) Microwave imaging via space-time beamforming for early detection of breast cancer. Antennas and Propagation, IEEE Transactions on 51(8):1690–1705
Boser BE, Guyon IM, Vapnik VN (1992) A training algorithm for optimal margin classifiers. In: Proceedings of the Fifth Annual Workshop on Computational Learning Theory, ACM, pp 144–152
Campbell C (2008) Introduction to support vector machines. http://videolectures.net/epsrcws08_campbell_isvm/
Chambers D, Berryman J (2006) Target characterization using decomposition of the time-reversal operator: electromagnetic scattering from small ellipsoids. Inverse Problems 22(6):2145–2163
Chen CC, Peters Jr L (1997) Buried unexploded ordnance identification via complex natural resonances. Antennas and Propagation, IEEE Transactions on 45(11):1645–1654
Chen Y, Gunawan E, Low KS, Wang SC, Soh CB, Putti TC (2008) Effect of lesion morphology on microwave signature in 2-d ultra-wideband breast imaging. Biomedical Engineering, IEEE Transactions on 55(8):2011–2021
Chen Y, Craddock IJ, Kosmas P (2010a) Feasibility study of lesion classification via contrast-agent-aided UWB breast imaging. Biomedical Engineering, IEEE Transactions on 57(5):1003–1007
Chen Y, Craddock IJ, Kosmas P, Ghavami M, Rapajic P (2010b) Multiple-input multiple-output radar for lesion classification in ultrawideband breast imaging. Selected Topics in Signal Processing, IEEE Journal of 4(1):187–201
Conceição R (2010) The development of ultra wideband scanning techniques for detection and classification of breast cancer. PhD thesis, National University of Ireland, Galway
Conceição R, O’Halloran M, Glavin M, Jones E (2011a) Evaluation of features and classifiers for classification of early-stage breast cancer. Journal of Electromagnetic Waves and Applications 25(1):1–14
Conceição RC, O’Halloran M, Glavin M, Jones E (2010) Support vector machines for the classification of early-stage breast cancer based on radar target signatures. Progress In Electromagnetics Research B 23:311–327, DOI 10.2528/PIERB10062407, http://www.jpier.org/pierb/pier.php?paper=10062407
Conceição RC, O’Halloran M, Glavin M, Jones E (2011b) Effects of dielectric heterogeneity in the performance of breast tumour classifiers. Progress In Electromagnetics Research M 17:73–86, DOI 10.2528/PIERM10122402, http://www.jpier.org/pierm/pier.php?paper=10122402
Conceição RC, O’Halloran M, Glavin M, Jones E (2011c) Numerical modelling for ultra wideband radar breast cancer detection and classification. Progress In Electromagnetics Research B 34:145–171, DOI 10.2528/PIERB11072705, http://www.jpier.org/pierb/pier.php?paper=11072705
Cortes C, Vapnik V (1995) Support-vector networks. Machine learning 20(3):273–297
Davis SK, Van Veen BD, Hagness SC, Kelcz F (2008) Breast tumor characterization based on ultrawideband microwave backscatter. Biomedical Engineering, IEEE Transactions on 55(1):237–246
Deboeck G, Kohonen T (1998) Visual explorations in finance: with self-organizing maps. Springer-Verlag London Ltd., UK
El-Shenawee M, Miller EL (2006) Spherical harmonics microwave algorithm for shape and location reconstruction of breast cancer tumor. Medical Imaging, IEEE Transactions on 25(10):1258–1271
Everitt BS, Dunn G (2001) Applied multivariate data analysis, 2nd edn. Arnold London, UK
Flores-Tapia D, Pistorius S (2011) Real time breast microwave radar image reconstruction using circular holography: A study of experimental feasibility. Medical physics 38(10):5420–5431
Gävert H, Hurri J, Särelä J, Hyvärinen A (2010) The fastica package for matlab. http://www.cis.hut.fi/projects/ica/fastica
Ghavami M, Michael LB, Haruyama S, Kohno R (2002) A novel uwb pulse shape modulation system. Wireless Personal Communications 23(1):105–120
Goldberg DE, Richardson J (1987) Genetic algorithms with sharing for multimodal function optimization. In: Genetic algorithms and their applications: Proceedings of the Second International Conference on Genetic Algorithms, pp 41–49
Haimovich AM, Blum RS, Cimini LJ (2008) MIMO radar with widely separated antennas. Signal Processing Magazine, IEEE 25(1):116–129
Hair JF, Black WC, Babin BJ, Anderson RE, Tatham RL (2006) Multivariate data analysis, 6th edn. Pearson Prentice Hall Upper Saddle River, New Jersey, USA
Holland JH (1992) Adaptation in natural and artificial systems: an introductory analysis with applications to biology, control, and artificial intelligence. MIT Press, Cambridge, MA, USA
Hsu CW, Chang CC, Lin CJ (2003) A practical guide to support vector classification. National Taiwan U. http://www.csie.ntu.edu.tw/cjlin/papers/guide/guidepdf
Hyvärinen A, Oja E (2000) Independent component analysis: algorithms and applications. Neural networks 13(4–5):411–430
Jones M, Byrne D, McGinley B, Morgan F, Glavin M, Jones E, O’Halloran M, Conceição RC (2013) Classification and monitoring of early stage breast cancer using ultra wide band radar. In: The Eighth International Conference on Systems (ICONS), International Academy, Research, and Industry Association (IARIA), pp 46–51
Kohonen T (1990) The self-organizing map. Proceedings of the IEEE 78(9):1464–1480
Kosmas P, Rappaport CM (2006) FDTD-based time reversal for microwave breast cancer detection-localization in three dimensions. Microwave Theory and Techniques, IEEE Transactions on 54(4):1921–1927
Kosmas P, Laranjeira S, Dixon J, Li X, Chen Y (2010) Time reversal microwave breast imaging for contrast-enhanced tumor classification. In: Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE, pp 708–711
Krzanowski WJ (1988) Principles of Multivariate Analysis: A User’s Perspective. Oxford Statistical Science Series. Oxford University Press, New York, USA
Lazebnik M, Popovic D, McCartney L, Watkins CB, Lindstrom MJ, Harter J, Sewall S, Ogilvie T, Magliocco A, Breslin TM, et al (2007) A large-scale study of the ultrawideband microwave dielectric properties of normal, benign and malignant breast tissues obtained from cancer surgeries. Physics in Medicine and Biology 52(20):6093–6115
Li J, Stoica P (2007) Mimo radar with colocated antennas. Signal Processing Magazine, IEEE 24(5):106–114
Li Y, Santorelli A, Laforest O, Coates M (2015) Cost-sensitive ensemble classifiers for microwave breast cancer detection. In: 2015 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), IEEE, pp 952–956
Maass W (1997) Networks of spiking neurons: the third generation of neural network models. Neural networks 10(9):1659–1671
Maass W (1999) Computing with spiking neurons. Pulsed Neural Networks
Mallat SG (1989) A theory for multiresolution signal decomposition: the wavelet representation. Pattern Analysis and Machine Intelligence, IEEE Transactions on 11(7):674–693
Mallet Y, Coomans D, Kautsky J, De Vel O (1997) Classification using adaptive wavelets for feature extraction. Pattern Analysis and Machine Intelligence, IEEE Transactions on 19(10):1058–1066
Mashal A, Booske JH, Hagness SC (2009a) Toward contrast-enhanced microwave-induced thermoacoustic imaging of breast cancer: An experimental study of the effects of microbubbles on simple thermoacoustic targets. Physics in medicine and biology 54(3):641–650
Mashal A, Sitharaman B, Booske JH, Hagness SC (2009b) Dielectric characterization of carbon nanotube contrast agents for microwave breast cancer detection. In: Antennas and Propagation Society International Symposium, 2009. APSURSI’09. IEEE, pp 1–4
McGinley B, O’Halloran M, Conceição RC, Morgan F, Glavin M, Jones E (2010) Spiking neural networks for breast cancer classification using radar target signatures. Progress In Electromagnetics Research C 17:79–94
Meaney PM, Fanning MW, Raynolds T, Fox CJ, Fang Q, Kogel CA, Poplack SP, Paulsen KD (2007) Initial clinical experience with microwave breast imaging in women with normal mammography. Academic Radiology 14(2):207–218
Medeiros HF (2013) Classificação de tumores de cancro na mama através de radar de banda ultra-larga de microondas. PhD thesis, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, http://run.unl.pt/bitstream/10362/11483/1/Medeiros_2013.pdf
Mishchenko MI, Hovenier JW, Travis LD (1999) Light scattering by nonspherical particles: theory, measurements, and applications, Academic press, chap Chapter 11: Light scattering by stochastically shaped particles
Muinonen K (1998) Introducing the gaussian shape hypothesis for asteroids and comets. Astronomy and Astrophysics 332:1087–1098
Ng A (2010) Support vector machines (part v of cs229 machine learning course materials). http://www.stanford.edu/class/cs229/notes/cs229-notes3.pdf
O’Halloran M, Cawley S, McGinley B, Conceição RC, Morgan F, Jones E, Glavin M (2011a) Evolving spiking neural network topologies for breast cancer classification in a dielectrically heterogeneous breast. Progress In Electromagnetics Research Letters 25:153–162, DOI 10.2528/PIERL11050605, http://www.jpier.org/pierl/pier.php?paper=11050605
O’Halloran M, McGinley B, Conceição RC, Morgan F, Jones E, Glavin M (2011b) Spiking neural networks for breast cancer classification in a dielectrically heterogeneous breast. Progress In Electromagnetics Research 113:413–428, DOI 10.2528/PIER10122203, http://www.jpier.org/pier/pier.php?paper=10122203
Oliveira B, Glavin M, Jones E, O’Halloran M, Conceição R (2014) Avoiding unnecessary breast biopsies: Clinically-informed 3d breast tumour models for microwave imaging applications. In: Antennas and Propagation Society International Symposium (APSURSI), 2014 IEEE, IEEE, pp 1143–1144
Oliveira B, O’Halloran M, Conceição R, Glavin M, Jones E (2015) Development of clinically-informed 3d tumor models for microwave imaging applications. accepted in IEEE Antennas and Wireless Propagation Letters DOI:10.1109/LAWP.2015.2456051
Pande S, Morgan F, Cawley S, McGinely B, Carrillo S, Harkin J, McDaid L (2010) EMBRACE-SysC for analysis of NoC-based spiking neural network architectures. In: International Symposium on System-on-Chip, IEEE
Prada C (2002) Detection and imaging in complex media with the D.O.R.T method. In: Imaging of complex media with acoustic and seismic waves, Springer, pp 107–134
Rangayyan RM, El-Faramawy NM, Desautels JEL, Alim O, et al (1997) Measures of acutance and shape for classification of breast tumors. Medical Imaging, IEEE Transactions on 16(6):799–810
Raykov T, Marcoulides GA (2008) An introduction to applied multivariate analysis. Routledge Taylor & Francis Group. New York, USA
Richmond JH (1965) Scattering by a dielectric cylinder of arbitrary cross section shape. Antennas and Propagation, IEEE Transactions on 13(3):334–341
Rocke P, McGinley B, Maher J, Morgan F, Harkin J (2008) Investigating the suitability of FPAAs for evolved hardware spiking neural networks. In: Evolvable Systems: From Biology to Hardware, Springer, pp 118–129
Roussinov DG, Chen H (1998) A scalable self-organizing map algorithm for textual classification: A neural network approach to thesaurus generation. Communication and Cognition in Artificial Intelligence Journal 15(1–2):81–112
Saito N, Coifman RR (1995) Local discriminant bases and their applications. Journal of Mathematical Imaging and Vision 5(4):337–358
Santorelli A, Li Y, Porter E, Popović M, Coates M (2014a) Image classification for a time-domain microwave radar system: Experiments with stable modular breast phantoms. In: 2014 8th European Conference on Antennas and Propagation (EuCAP), IEEE, pp 320–324
Santorelli A, Porter E, Kirshin E, Liu YJ, Popović M (2014b) Investigation of classifiers for tumor detection with an experimental time-domain breast screening system. Progress In Electromagnetics Research 144(2):45–57
Santorelli A, Laforest O, Porter E, Popović M (2015) Image classification for a time-domain microwave radar system: Experiments with stable modular breast phantoms. In: 2015 9th European Conference on Antennas and Propagation (EuCAP), IEEE, pp 1–5
Saunders R, Samei E, Baker J, Delong D (2006) Simulation of mammographic lesions. Academic radiology 13(7):860–870
Scott MJJ, Niranjan M, Prager RW (1998) Realisable classifiers: Improving operating performance on variable cost problems. In: BMVC, pp 306–315
Seber GAF (1984) Multivariate observations. John Wiley & Sons, New Jersey, USA
Serrano-Cinca C (1996) Self organizing neural networks for financial diagnosis. Decision Support Systems 23(3):227–238
Shea JD, Kosmas P, Hagness SC, Van Veen BD (2009) Contrast-enhanced microwave breast imaging. In: Antenna Technology and Applied Electromagnetics and the Canadian Radio Science Meeting, 2009. ANTEM/URSI 2009. 13th International Symposium on, IEEE, pp 1–4
Shlens J (2003) A tutorial on principal component analysis. http://www.cs.princeton.edu/picasso/mats/PCA-Tutorial-Intuition_jp.pdf
Sill JM, Fear EC (2005) Tissue sensing adaptive radar for breast cancer detection-experimental investigation of simple tumor models. Microwave Theory and Techniques, IEEE Transactions on 53(11):3312–3319
Stanley KO, Miikkulainen R (2002) Evolving neural networks through augmenting topologies. Evolutionary computation 10(2):99–127
Teo J, Chen Y, Soh CB, Gunawan E, Low KS, Putti TC, Wang SC (2010) Breast lesion classification using ultrawideband early time breast lesion response. Antennas and Propagation, IEEE Transactions on 58(8):2604–2613
Valens C (1999–2010) A really friendly guide to wavelets. http://pagesperso-orange.fr/polyvalens/clemens/wavelets/wavelets.html#section1
Veeravalli VV, Basar T, Poor HV (1994) Minimax robust decentralized detection. Information Theory, IEEE Transactions on 40(1):35–40
Wasilewski F (2010) Pywavelets - coiflets 5 wavelet (coif5) properties, filters and functions - wavelet properties browser. http://wavelets.pybytes.com/wavelet/coif5
Wickerhauser MV (1994) Adapted wavelet analysis from theory to software. AK Peters Ltd., MA, USA
Wold H, et al (1966) Multivariate analysis, Academic Press, New York, USA, chap Estimation of principal components and related models by iterative least squares, pp 391–420
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Conceição, R.C., Jones, M., Kosmas, P., Chen, Y. (2016). Tumour Classification. In: Conceição, R., Mohr, J., O'Halloran, M. (eds) An Introduction to Microwave Imaging for Breast Cancer Detection. Biological and Medical Physics, Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-27866-7_5
Download citation
DOI: https://doi.org/10.1007/978-3-319-27866-7_5
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-27865-0
Online ISBN: 978-3-319-27866-7
eBook Packages: Physics and AstronomyPhysics and Astronomy (R0)