Abstract
Wilms tumor, or nephroblastoma, is the most common primary malignant renal tumor and the second most frequent solid organ abdominal tumor of childhood. Outcomes for children with Wilms tumor have improved dramatically over the last 50 years with long-term survival in both North America and Europe approaching 85 %. Furthermore, many of the low-stage tumors have survival rates between 99 %. The treatment strategy for children with a WT is based on several factors including, demographic, pathologic, genetic, and response to therapy. The current strategy is risk based, with the goals of maximizing the likelihood of cure while minimizing late effects.
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Cozzi DA, Ceccanti S, Cozzi F. Renal Function of Patients With Synchronous Bilateral Wilms Tumor. Ann Surg. 2016
Dome JS, Cotton CA, Perlman EJ, et al. Treatment of anaplastic Histology Wilms’ tumor: results from the fifth National Wilms’ Tumor Study. J Clin Oncol. 2006;24(15):2352–8.
Ehrlich PF, Hamilton TE, Gow K, et al. Surgical protocol violations in children with renal tumors provides an opportunity to improve pediatric cancer care: a report from the Children’s Oncology Group. Pediatr Blood Cancer. 2016
Ehrlich PF, Hamilton TE, Grundy PE, et al. The value of surgery in directing therapy of Wilms tumor patients with pulmonary disease: a report from The National Wilms Tumor Study Group (NWTS −5). J Pediatr Surg. 2006;41(1):162–7.
Kieran K, Ehrlich PF. Current surgical standards of care in Wilms tumor. Urol Oncol. 2016 34(1):13–23
Lall A, Pritchard-Jones K, Walker J, et al. Wilms’ tumor with intracaval thrombus in the UK Children’s Cancer Study Group UKW3 trial. J Pediatr Surg. 2006 Feb;41(2):382–7
Malkan AD, Loh A, Bahrami A, et al. An approach to renal masses in pediatrics. Pediatrics. 2015;135(1):142–58
Perlman EJ, Faria P, Soares A, Hoffer FA, et al. Hyperplastic perilobar nephroblastomatosis: Long term survival in 52 patients. Pediatr Blood Cancer. 2006;46:203–21.
Shamberger RC, Haase G, Argani P. Bilateral Wilms’ tumors with progressive or nonresponsive disease. J Pediatr Surg. 2006;41(4):652–7.
Shamberger RC, Ritchey ML, Haase GM, et al. Intravascular extension of Wilms tumor. Ann Surg. 2001;234(1):116–21.
Stewart CL, Bruny JL. Maximizing lymph node retrieval during surgical resection of Wilms tumor. Eur J Pediatr Surg. 2015;25(1):109–12
Sulkowski J, Kolon T, Mattei P. Nephron-sparing partial nephrectomy for bilateral Wilms’ tumor. J Pediatr Surg. 2012 Jun;47(6):1234–8
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Ehrlich, P.F. (2017). Wilms Tumor. In: Mattei, P., Nichol, P., Rollins, II, M., Muratore, C. (eds) Fundamentals of Pediatric Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-27443-0_97
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DOI: https://doi.org/10.1007/978-3-319-27443-0_97
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