Skip to main content

Anti-ulcer Activity

  • Chapter
  • First Online:
Pharmacological Assays of Plant-Based Natural Products

Part of the book series: Progress in Drug Research ((PDR,volume 71))

  • 1903 Accesses

Abstract

This chapter explains the procedure of ethanol-induced ulcer to check the protective effect of drugs over induced ulcer in rats. Ulcer is defined as the erosion in the lining of the stomach or duodenum and is caused by the disruptions of the gastric mucosal defence and repair systems. Ulceration of stomach is called gastric ulcer and that of duodenum is called duodenal ulcer and together peptic ulcer. In clinical practice, peptic ulcer is one of the most prevalent gastrointestinal disorders, which commonly occurs in developed countries.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Abdulla, M. A., Ahmed, K. A. A., Al-Bayaty, F. H., & Masood, Y. (2010). Gastroprotective effect of Phyllanthus niruri leaf extract against ethanol-induced gastric mucosal injury in rats. African Journal of Pharmacy and Pharmacology, 4, 226–230.

    Google Scholar 

  • Kulkarni, S. K. (2002). Hand book of experimental pharmacology (pp. 149–150). New Delhi: Vallabh Prakashan.

    Google Scholar 

  • Paiva, L. A. F., Rao, V. S. N., Gramosa, N. V., & Silveira, F. R. (1998). Gastroprotective effect of Copaifera langsdorffii oleo-resin on experimental gastric ulcer models in rats. Journal of Ethnopharmacology, 62, 73–78.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Parimelazhagan Thangaraj .

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Thangaraj, P. (2016). Anti-ulcer Activity. In: Pharmacological Assays of Plant-Based Natural Products. Progress in Drug Research, vol 71. Springer, Cham. https://doi.org/10.1007/978-3-319-26811-8_21

Download citation

Publish with us

Policies and ethics