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Antenatal Screening/Prenatal Diagnosis

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Clinical Embryology
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Abstract

As care providers for pregnant women and their babies, the ultimate goal is always a healthy mother and a healthy baby.

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References

  1. Palomaki GE, Kloza EM, Lambert-Messerlian GM, Haddow JE, Neveux LM, Ehrich M, et al. DNA sequencing of maternal plasma reliably identifies trisomy 18 and trisomy 13 as well as Down’s syndrome: an international collaborative study. Genet Med. 2012;14:296–305.

    Article  CAS  Google Scholar 

  2. NHS Fetal anomaly screening programme Annual Report. NHS FASP April 2010-March 2011. London: UK National Screening Programmes Directorate, 2011.

    Google Scholar 

  3. Ward P, Soothill P. Fetal anomaly ultrasound scanning: the development of a national screening programme for England. Obstet Gynaecol. 2011;13:211–7.

    Google Scholar 

  4. Khalil A, Mahmoodian N, Kulkarni A, Homfray T, Papageorghiou A, Bhide A, Thilaganathan B. Estimation of detection rates of aneuploidy in high-risk pregnancy using an approach based on nuchal translucency and non-invasive prenatal testing: a cohort study. Fetal Diagn Ther. 2015;38(4):254–61.

    Article  Google Scholar 

  5. Spencer K, Spencer CE, Power M, Moakes A, Nicolaides KH. One stop clinic for assessment of risk for fetal anomalies: a report of the first year of prospective screening for chromosomal anomalies in the first trimester. BJOG. 2000;107:1271–5.

    Article  CAS  Google Scholar 

  6. Baer RJ, Flessel MC, Jelliffe-Pawlowski LL, Goldman S, Hudgins L, Hull AD, et al. Detection rates for aneuploidy by first-trimester and sequential screening. Obstet Gynecol. 2015;126:753–9.

    Article  Google Scholar 

  7. Gil MM, Revello R, Poon LC, Akolekar R, Nicolaides KH. Clinical implementation of routine screening for fetal trisomies in the UK NHS: cell-free DNA test contingent on results from first-trimester combined test. Ultrasound Obstet Gynecol. 2016;47:45–52.

    Article  CAS  Google Scholar 

  8. Anandakumar C, Wong YC, Annapoorna V, Arulkumaran S, Chia D, Bongso A, et al. Amniocentesis and its complications. Aust NZ J Obstet Gynecol. 1992;32:97–9.

    Article  CAS  Google Scholar 

  9. Odibo AO, Dicke JM, Gray DL, Oberie B, Stamilio DM, Macones GA, et al. Evaluating the rate and risk factors for fetal loss following CVS. Obstet Gynecol. 2008;112:813–9.

    Article  Google Scholar 

  10. Campbell S. Early prenatal diagnosis of neural tube defects by ultrasound. Clin Obstet Gynecol. 1977;20:351–9.

    Article  CAS  Google Scholar 

  11. Chaoui R, Nicolaides KH. From nuchal translucency to intracranial translucency, towards the early detection of spina bifida. Ultrasound Obstet Gynecol. 2010;35(2):133–8.

    Article  CAS  Google Scholar 

  12. Donald I, Mac Vicar J, Brown TG. Investigation of abdominal masses by pulsed ultrasound. Lancet. 1958;1:1188–95.

    Article  CAS  Google Scholar 

  13. Donald I. Clinical applications of ultrasonic technology in obstetrical and gynecological diagnosis. Br J Obstet Gynecol. 1962;69:1036.

    Article  CAS  Google Scholar 

  14. Bencerraf BR, Barss VA, Laboda LA. A sonographic sign for the detection in the second trimester of the fetus with Down’s syndrome. Am J Obstet Gynecol. 1985;151:1078–9.

    Article  Google Scholar 

  15. Nicolaides KH, Azar GB, Byrne D. Nuchal translucency: ultrasound screening for chromosomal defects in the first trimester of pregnancy. Br Med J. 1992;304:867–9.

    Article  CAS  Google Scholar 

  16. Hubbard AM. Ultrafast fetal MRI and prenatal diagnosis. Semin Pediatr Surg. 2003;12:143–53.

    Article  Google Scholar 

  17. Levine D, Fetal MRI. J Matern Fetal Neonatal Med. 2004;15:85–94.

    Article  CAS  Google Scholar 

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Correspondence to Nicola Brindley .

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Brindley, N. (2019). Antenatal Screening/Prenatal Diagnosis. In: Carachi, R., Doss, S. (eds) Clinical Embryology. Springer, Cham. https://doi.org/10.1007/978-3-319-26158-4_7

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  • DOI: https://doi.org/10.1007/978-3-319-26158-4_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-26156-0

  • Online ISBN: 978-3-319-26158-4

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