Skip to main content

Abdominal Wall Defects

  • Chapter
  • First Online:
Clinical Embryology
  • 2724 Accesses

Abstract

Abdominal wall defects can be divided into two groups depending on their embryological origins: gastroschisis, ectopia cordis and bladder exstrophy in one group and exomphalos in the other [1]. In practice, there is an overlap particularly with regard to bladder exstrophy, pentalogy of Cantrell and exomphalos. This chapter will focus on gastroschisis and exomphalos with bladder exstrophy being discussed elsewhere in the book.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Prefumo F, Izzi C. Fetal abdominal wall defects. Best Pract Res Clin Obstet Gynaecol. 2014;28:391–402.

    Article  Google Scholar 

  2. Sadler TW. The embryologic origin of ventral body wall defects. Semin Pediatr Surg. 2010;19:209–14.

    Article  Google Scholar 

  3. Duhamel B. Embryology of exomphalos and other ventral body wall defects. Arch Dis Child. 1963;38:142–7.

    Article  CAS  Google Scholar 

  4. Miller SA. Differential proliferation in morphogenesis of lateral body wall folds. J Exp Zool. 1982;221:2005–11.

    Article  Google Scholar 

  5. Shaw A. The myth of gastroschisis. J Pediatr Surg. 1975;10:235–44.

    Article  CAS  Google Scholar 

  6. Sadler TW, Feldkamp ML. The embryology of body wall closure: relevance to gastroschisis and other ventral body wall defects. Am J Med Genet C Semin Med Genet. 2008;148C:180–5.

    Article  CAS  Google Scholar 

  7. deVries PA. The pathogenesis of Gastroschisis and omphalocele. J Pediatr Surg. 1980;15:245–51.

    Article  CAS  Google Scholar 

  8. Feldcamp ML, Carey JC, Sadler TW. Development of gastroschisis: review of hypothesis and implications for research. Am J Med Genet. 2007;143A:639–52.

    Article  Google Scholar 

  9. Hoyme HE, Higginbottom MC, Jones KL. The vascular pathogenesis: intrauterine interruption of the omphalomesenteric artery. J Pediatr Surg. 1981;98:228–31.

    CAS  Google Scholar 

  10. Stevenson RE, Rodgers RC, Chandler JC, et al. Escape of the yolk sac: a hypothesis to explain embryogenesis of gastroschisis. Clin Genet. 2009;75:326–33.

    Article  CAS  Google Scholar 

  11. Loan M, Dolk H, Bradbury I. Increasing prevalence of gastroschisis in Europe 1980-2002: a phenomenon restricted to younger mothers? Paediatr Perinat Epidemiol. 2007;21:363–9.

    Article  Google Scholar 

  12. Christison ER, Kelleher CM, Langer JC. Neonatal abdominal wall defects. Semin Fetal Neonatal Med. 2011;16:164–72.

    Article  Google Scholar 

  13. Kuleva M, Khen-Dunlop N, Dumez Y. Is complex gastroschisis predictable by neonatal ultrasound? BJOG. 2011;119:102–9.

    Article  Google Scholar 

  14. Lausman AY, Langer JC, Tai M, et al. Gastroschisis: what is the average gestational age of spontaneous delivery? J Pediatr Surg. 2007;42:1816–21.

    Article  Google Scholar 

  15. Charlesworth P, Njere I, Alloytey J. Postnatal outcome in gastroschisis: effect of birth weight and gestational age. J Pediatr Surg. 2007;42:815–8.

    Article  Google Scholar 

  16. Luton D, de Lagausie P, Guibourdenche J, et al. Effect of amnioinfusion on the outcome of prenatally diagnosed gastroschisis. Fetal Diagn Ther. 1999;14(3):152–5.

    Article  CAS  Google Scholar 

  17. Gamba P, Midrio P. Prenatal diagnosis, newborn management and long-term outcomes. Semin Pediatr Surg. 2014;23:283–90.

    Article  Google Scholar 

  18. Holcomb GW III, Murphy JP. Ashcraft’s pediatric surgery (5th Ed). Philadelphia: Saunders Elsevier.

    Chapter  Google Scholar 

  19. Brantberg A, Blaas HGK, et al. Characteristics and outcome in 90 cases of fetal exomphalos. Ultrasound Obstet Gynecol. 2005;26:527–37.

    Article  CAS  Google Scholar 

  20. Van Eijck FC, Hoogeveen YL, van Weel C, et al. Minor and giant omphalocele: long-term outcomes and quality of life. J Pediatr Surg. 2009;44:1355–9.

    Article  Google Scholar 

  21. Segal SY, Marder SJ, Parry S, et al. Fetal abdominal wall defects and mode of delivery: a systematic review. Obstet Gynecol. 2001;98(5):867–73.

    Google Scholar 

  22. Zaccara A, Lacobelli BD, Calzolari A, et al. Cardiopulmonary performances in young children and adolescents born with large abdominal wall defects. J Pediatr Surg. 2003;38:478–81.

    Article  CAS  Google Scholar 

  23. Engum SA. Embryology, sternal clefts, ectopia cordis and Cantrell’s pentalogy. Semin Pediatr Surg. 2008;17:154–60.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lynne A. Mcintosh .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Mcintosh, L.A. (2019). Abdominal Wall Defects. In: Carachi, R., Doss, S. (eds) Clinical Embryology. Springer, Cham. https://doi.org/10.1007/978-3-319-26158-4_32

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-26158-4_32

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-26156-0

  • Online ISBN: 978-3-319-26158-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics