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Cerebellar Closed-Loops

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Essentials of Cerebellum and Cerebellar Disorders

Abstract

Data from histological tracing studies in non-human primate strongly support the view that the cerebellar system is organized into distinct, motor and non-motor, parallel closed-loop circuits interconnecting the cerebellum and the cerebral cortex. Functional imaging data in human seem to confirm this specific network organization in human, and to extend the role of the cerebellum from motor control to regulation of cognition and emotion.

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References

  • Allen G, McColl R, Holly B, Ringe WK, Fleckenstein J, Cullum CM (2005) Magnetic resonance imaging of cerebellar-prefrontal and cerebellar-parietal functional connectivity. Neuroimage 28:39–48

    Article  PubMed  Google Scholar 

  • Bernard JA, Peltier SJ, Benson BI, Wiggins JL, Jaeggi SM, Buschkuehl M, Jonides J, Monk CS, Seidler RD (2014) Dissociable networks of the human dentate nucleus. Cereb Cortex 24:2151–2159

    Article  PubMed  Google Scholar 

  • Bostan AC, Dum RP, Strick PL (2010) The basal ganglia communicates with the cerebellum. PNAS USA 107:8452–8456

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Buckner RL, Krienen FM, Castellanos A et al (2011) The organization of the human cerebellum estimated by intrinsic functional connectivity. J Neurophysiol 106:1125–1165

    Article  PubMed  PubMed Central  Google Scholar 

  • Clower DM, West RA, Lynch JC et al (2001) The inferior parietal lobule is the target of output from superior colliculus, hippocampus, and cerebellum. J Neurosci 21:6283–6291

    CAS  PubMed  Google Scholar 

  • Dum RP, Strick PL (2003) An unfolded map of the cerebellar dentate nucleus and its projection to the cerebral cortex. J Neurophysiol 89:634–639

    Article  PubMed  Google Scholar 

  • Habas C, Cabanis EA (2007) Anatomical parcellation of the brainstem and cerebellar white matter: a preliminary probabilistic tractography study at 3 T. Neuroradiology 49:849–863

    Article  PubMed  Google Scholar 

  • Habas C, Kamdar N, Nguyen D, Prater K, Beckmann CF, Menon V, Greicius MD (2009) Distinct cerebellar contributions to intrinsic connectivity networks. J Neurosci 29:8586–8594

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hoshi E, Tremblay L, Féger J, Carras PL, Strick PL (2005) The cerebellum communicates with the basal ganglia. Nat Neurosci 8:1491–1493

    Article  CAS  PubMed  Google Scholar 

  • Jissendi P, Baudry S, Balériaux D (2008) Diffusion tensor imaging (DTI) and tractography of the cerebellar projections to prefrontal and posterior parietal cortices: a study at 3 T. J Neuroradiol 35:42–50

    Article  CAS  PubMed  Google Scholar 

  • Kelly RM, Strick PL (2003) Cerebellar loops with motor cortex and prefrontal cortex of a nonhuman primate. J Neurosci 23: 8432–8444

    Google Scholar 

  • Krienen FM, Buckner RL (2009) Segregated fronto-cerebellar circuits revealed by intrinsic functional connectivity. Cerebr Cortex 19:2485–2497

    Article  Google Scholar 

  • Middleton FA, Strick PL (2001) Cerebellar projections to the prefrontal cortex of the primate. J Neurosci 15:700–712

    Google Scholar 

  • O’Reilly JX, Beckmann CF, Tomassini V, Ramnani N, Johansen-Berg H (2009) Distinct and overlapping functional zones in the cerebellum defined by resting state functional connectivity. Cereb Cortex 20:953–965

    Article  PubMed  PubMed Central  Google Scholar 

  • Palesi F, Tournier J-D, Calamante F et al (2015) Contralateral cerebello-thalamo-cortical pathways with prominent involvement of associative areas in humans in vivo. Brain Struct Funct 220:3369–3384

    Google Scholar 

  • Ramnani N (2006) The primate cortico-cerebellar system: anatomy and function. Nat Rev Neurosci 7:511–522

    Article  CAS  PubMed  Google Scholar 

  • Salmi J, Pallesen KJ, Neuvonen T, Brattico E, Korvenoja A, Salonen CS (2010) Cognitive and motor loops of the human cerebro-cerebellar system. J Cogn Neurosci 22:2663–2676

    Article  PubMed  Google Scholar 

  • Schmahmann JD, Pandya DN (1997) The cerebrocerebellar system. Int Rev Neurobiol 41:31–60

    Article  CAS  PubMed  Google Scholar 

  • Strick PL, Dum RP, Fiez JA (2009) Cerbellum and nonmotor function. Annu Rev Neurosci 32:413–434

    Google Scholar 

  • Voogd J, Schraa-Tam CKL, van der Geest JN et al (2012) Visuomotor cerebellum in human and non human primates. Cerebellum 11:392–410

    Article  PubMed  Google Scholar 

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Correspondence to Christophe Habas .

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Habas, C. (2016). Cerebellar Closed-Loops. In: Gruol, D., Koibuchi, N., Manto, M., Molinari, M., Schmahmann, J., Shen, Y. (eds) Essentials of Cerebellum and Cerebellar Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-24551-5_47

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