Abstract
Modern neuroscience is paving the way for new insight into cerebellar functions including the control of cognitive, autonomic and emotional processes. Yet, how the cerebellum coordinates basic motor behavior such as locomotion is still only partly understood. Here, we will review the role of the cerebellum in locomotion from the perspective of neuro-anatomical and clinical reports as well as cell-specific rodent studies. Evidence has been emerging that different modules and networks exert synergistic roles in the preparation, performance, adaptation and consolidation of locomotion, highlighting their contribution to interlimb coordination and the accuracy, efficiency and regularity of locomotion patterns.
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Acknowledgements
This work was supported by the Dutch Organization for Medical Sciences (ZonMw), Life Sciences (ALW), Senter (Neuro-Bsik) and ERC-adv of the European Community.
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da Silva Matos, C., Vinueza Veloz, M.F., Ruigrok, T.J.H., De Zeeuw, C.I. (2016). Cerebellar Modules and Networks Involved in Locomotion Control. In: Gruol, D., Koibuchi, N., Manto, M., Molinari, M., Schmahmann, J., Shen, Y. (eds) Essentials of Cerebellum and Cerebellar Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-24551-5_37
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