Abstract
Vitamin D is a steroid hormone that influences glucocorticoids and gonadal hormones, interfering with the immune system and estrogen-modulated cells. Therefore vitamin D deficiency is thought as a risk factor for several chronic inflammatory and autoimmune conditions.
A possible synergism between 1,25(OH)D3 and glucocorticoids could represent a new approach for the management of chronic autoimmune diseases.
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Paolino, S., Smith, V., Pizzorni, C., Seriolo, B., Sulli, A., Cutolo, M. (2016). Vitamin D, Autoimmune Diseases, and Systemic Lupus Erythematosus. In: Roccatello, D., Emmi, L. (eds) Connective Tissue Disease. Rare Diseases of the Immune System. Springer, Cham. https://doi.org/10.1007/978-3-319-24535-5_12
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