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Diabetes and Other Neurogenic Underactive Bladder Conditions

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The Underactive Bladder

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Abstract

Underactive bladder (UAB) can be resulted from a variety of neurologic diseases, including diabetes and other central and peripheral nervous system disorders. Pelvic surgery and trauma can also cause UAB. Diabetic patients with lower urinary tract symptoms, large bladder capacity, elevated residual urine volume, and urinary tract infections should undergo urodynamic evaluation. However, due to the asymptomatic character at the incipient stage of diabetic UAB, early diagnosis is still an unmet medical need. Careful urodynamic evaluation is essential in patients with neurogenic bladder dysfunction. Effective pharmacologic therapy for neurogenic UAB is still lacking and most patients with neurogenic UAB are treated with intermittent catheterization. We will review the scope of UAB in diabetes and other common neurological diseases in this chapter.

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References

  • Allgot B, Gan D, King H et al (2003) Diabetes atlas: executive summary, 2nd edn. International Diabetes Federation, Brussels

    Google Scholar 

  • Amarenco G, Chartier-Kastler E, Denys P, Jean JL, de Sèze M, Lubetzski C (2013a) First-line urological evaluation in multiple sclerosis: validation of a specific decision-making algorithm. Mult Scler J 19:1931–1937

    Article  Google Scholar 

  • Amarenco G, Raibaut P, Hubeaux K, Jousse M, Sheikh IS, Lapeyre E (2013b) Autonomic nervous system alteration in multiple sclerosis patients with urinary symptoms. Clinical, urodynamic and cardiovascular study. Prog Urol 23:1505

    Article  CAS  PubMed  Google Scholar 

  • Amarenco G, de Sèze M, Ruffion A, Sheikh Ismael S (2014) Clinical and urodynamic evaluations of urinary disorders in multiple sclerosis. Ann Phys Rehabil Med 57:277–287

    Article  CAS  PubMed  Google Scholar 

  • Andersson KE (2014) The many faces of impaired bladder emptying. Curr Opin Urol 24:363–369

    Article  PubMed  Google Scholar 

  • Bansal R, Agarwal MM, Modi M, Mandal AK, Singh SK (2011) Urodynamic profile of diabetic patients with lower urinary tract symptoms: association of diabetic cystopathy with autonomic and peripheral neuropathy. Urology 77:699–705

    Article  PubMed  Google Scholar 

  • Brittain K, Perry S, Peet S, Shaw C, Dallosso H, Assassa R, Williams K, Jagger C, Potter J, Castleden C (2000) Prevalence and impact of urinary symptoms among community-dwelling stroke survivors. Stroke 31:886–891

    Article  CAS  PubMed  Google Scholar 

  • Broseta E, Osca JM, Morera J, Martinez-Agullo E, Jimenez-Cruz JF (1993) Urological manifestations of herpes zoster. Eur Urol 24:244–247

    CAS  PubMed  Google Scholar 

  • Castel-Lacanal E, Game X, De Boissezon X, Guillotreau J, Braley-Berthoumieux E, Terracol C, Gasq D, Labrunee M, Viala F, Rischmann P, Clanet M and Marque P (2013) Impact of intermittent catheterization on the quality of life of multiple sclerosis patients. World J Urol 31:1445–1450

    Google Scholar 

  • Chancellor MB, Blaivas JG (1995) Chapter 14. Diabetic neurogenic bladder. In: Chancellor MB, Blaivas JG (eds) Practical neuro-urology: genitourinary complications in neurologic disease. Butterworth Heinemann, Stoneham, pp 149–154

    Google Scholar 

  • Chang CH, Shau WY, Jiang YD et al (2010) Type 2 diabetes prevalence and incidence among adults in Taiwan during 1999–2004: a national health insurance data set study. Diabet Med 27:636–643

    Article  CAS  PubMed  Google Scholar 

  • Chen PH, Hsueh HF, Hong CZ (2002) Herpes zoster-associated voiding dysfunction: a retrospective study and literature review. Arch Phys Med Rehabil 83:1624–1628

    Article  PubMed  Google Scholar 

  • Daneshgari F, Liu G, Birder L, Hanna-Mitchell AT, Chacko S (2009) Diabetic bladder dysfunction: current translational knowledge. J Urol 182:S18–S26

    Article  CAS  PubMed  Google Scholar 

  • de Sèze M, Ruffion A, Denys P, Joseph P-A, Perrouin-Verbe B & group IFN-Ues (2007) The neurogenic bladder in multiple sclerosis: review of the literature and proposal of management guidelines. Mult Scler 13:915–928

    Article  PubMed  Google Scholar 

  • Dong D, Xu Z, Shi B, Chen J, Jiang X, Wang H (2006) Urodynamic study in the neurogenic bladder dysfunction caused by intervertebral disk hernia. Neurourol Urodyn 25:446–450

    Article  PubMed  Google Scholar 

  • Frimodt-Moller C (1980) Diabetic cystopathy: epidemiology and related disorders. Ann Intern Med 92:318–321

    Article  CAS  PubMed  Google Scholar 

  • Gilbaz E, Gungor Ugurlucan F, Aslay I, Yalcin O (2013) The effects of simple and radical hysterectomy and radiotherapy on lower urinary tract symptoms and urodynamics. Eur J Gynaecol Oncol 34:248–253

    CAS  PubMed  Google Scholar 

  • Guariguata L, Whiting DR, Hambleton I et al (2014) Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract 103:137–149

    Article  CAS  PubMed  Google Scholar 

  • Hagen EM, Rekand T (2014) Management of bladder dysfunction and satisfaction of life after spinal cord injury in Norway. J Spinal Cord Med 37:310–316

    Article  PubMed  PubMed Central  Google Scholar 

  • Han K-S, Heo SH, Lee S-J, Jeon SH, Yoo KH (2010) Comparison of urodynamics between ischemic and hemorrhagic stroke patients; Can we suggest the category of urinary dysfunction in patients with cerebrovascular accident according to type of stroke? NeurourolUrodyn 29:387–390

    Google Scholar 

  • Hattori T, Yasuda K, Kita K, Hirayama K (1990) Disorders of micturition in tabes dorsalis. Br J Urol 65:497–499

    Article  CAS  PubMed  Google Scholar 

  • Havenga K, Maas CP, DeRuiter MC, Welvaart K, Trimbos JB (2000) Avoiding long-term disturbance to bladder and sexual function in pelvic surgery, particularly with rectal cancer. Semin Surg Oncol 18:235–243

    Article  CAS  PubMed  Google Scholar 

  • He CX, Yuan ZY, Yan SB, Wu CW, Huang YC, He W et al (2014) Clinical and urodynamic evaluation of women referred with diabetes mellitus. Int Urogynecol J 25:979–983

    Article  Google Scholar 

  • Hellstrom P, Kortelainen P, Kontturi M (1986) Late urodynamic findings after surgery for cauda equina syndrome caused by a prolapsed lumbar intervertebral disk. J Urol 135:308–312

    CAS  PubMed  Google Scholar 

  • Kaplan SA, Te AE, Blaivas JG (1995) Urodynamic findings in patients with diabetic cystopathy. J Urol 153:342–344

    Article  CAS  PubMed  Google Scholar 

  • Kebapci N, Yenilmez A, Efe B, Entok E, Demirustu C (2007) Bladder dysfunction in type 2 diabetic patients. Neurourol Urodyn 26:814–819

    Article  PubMed  Google Scholar 

  • Kong KH, Young S (2000) Incidence and outcome of poststroke urinary retention: a prospective study. Arch Phys Med Rehabil 81:1464–1467

    Article  CAS  PubMed  Google Scholar 

  • Lawrence JM, Lukacz ES, Liu IL et al (2007) Pelvic floor disorders, diabetes, and obesity in women: findings from the Kaiser Permanente Continence Associated Risk Epidemiology Study. Diabetes Care 30:2536–2541

    Article  PubMed  Google Scholar 

  • Lebovitch S, Mydlo JH (2008) HIV-AIDS: urologic considerations. Urol Clin North Am 35:59–68

    Article  PubMed  Google Scholar 

  • Lee WC, Wu HP, Tai TY, Yu HJ, Chiang PH (2009) Investigation of urodynamic characteristics and bladder sensory function in the early stages of diabetic bladder dysfunction in women with type 2 diabetes. J Urol 181:198–203

    Article  PubMed  Google Scholar 

  • Leng WW, Chancellor MB (2005) How sacral nerve stimulation neuromodulation works. Urol Clin North Am 32:11–18

    Article  PubMed  Google Scholar 

  • Lin TL, Chen GD, Chen YC, Huang CN, Ng SC (2012) Aging and recurrent urinary tract infections are associated with bladder dysfunction in type 2 diabetes. Taiwan J Obstet Gynecol 51:381–386

    Article  PubMed  Google Scholar 

  • Litwiller SE, Frohman EM, Zimmern PE (1999) Multiple sclerosis and the urologist. J Urol 161:743–757

    Article  CAS  PubMed  Google Scholar 

  • Liu RT, Chung MS, Lee WC, Chang SW, Huang ST, Yang KD, Chancellor MB, Chuang YC (2011) Prevalence of overactive bladder (OAB) and associated risk factors in 1,359 patients with type 2 diabetes. Urology 78:1040–1045

    Article  PubMed  Google Scholar 

  • Miyazato M, Yoshimura N, Chancellor MB (2013) The other bladder syndrome: underactive bladder. Rev Urol 15:11–22

    PubMed  PubMed Central  Google Scholar 

  • Pizzi A, Falsini C, Martini M, Rossetti MA, Verdesca S, Tosto A (2014) Urinary incontinence after ischemic stroke: clinical and urodynamic studies. NeurourolUrodyn 33:420–425

    Google Scholar 

  • Rabadi MH, Aston C (2014) Complications and urologic risks of neurogenic bladder in veterans with traumatic spinal cord injury. Spinal Cord. doi:10.1038/sc.2014.205. PMID: 25403501

    PubMed  Google Scholar 

  • Sakakibara R, Uchiyama T, Kuwabara S, Mori M, Ito T, Yamamoto T, Awa Y, Yamaguchi C, Yuki N, Vernino S, Kishi M, Shirai K (2009) Prevalence and mechanism of bladder dysfunction in Guillain-Barre Syndrome. NeurourolUrodyn 28:432–437

    Google Scholar 

  • Sakakibara R, Tateno F, Nagao T, Yamamoto T, Uchiyama T, Yamanishi T, Yano M, Kishi M, Tsuyusaki Y, Aiba Y (2014) Bladder function of patients with Parkinson’s disease. Int J Urol 21:638–646

    Article  CAS  PubMed  Google Scholar 

  • Sasaki K, Yoshimura N, Chancellor MB (2003) Implications of diabetes mellitus in urology. Urol Clin North Am 30:1–12

    Article  PubMed  Google Scholar 

  • Tseng CJ, Shen HP, Lin YH, Lee CY, Wei-Cheng Chiu W (2012) A prospective study of nerve-sparing radical hysterectomy for uterine cervical carcinoma in Taiwan. Taiwan J Obstet Gynecol 51:55–59

    Article  PubMed  Google Scholar 

  • Uchiyama T, Sakakibara R, Yamamoto T, Ito T, Yamaguchi C, Awa Y, Yanagisawa M, Higuchi Y, Sato Y, Ichikawa T, Yamanishi T, Hattori T, Kuwabara S (2011) Urinary dysfunction in early and untreated Parkinson’s disease. J Neurol Neurosurg Psychiatry 82:1382–1386

    Article  PubMed  Google Scholar 

  • Van Poppel H, Stessens R, van Damme B et al (1988) Diabetic cystopathy: neuropathological examination of urinary bladder biopsies. Eur Urol 15:128–131

    PubMed  Google Scholar 

  • Wagner JR, Russo P (2000) Urologic complications of major pelvic surgery. Semin Surg Oncol 18:216–228

    Article  CAS  PubMed  Google Scholar 

  • Watanabe T, Miyagawa I (1999) Characteristics of detrusor contractility during micturition in diabetics. Neurourol Urodyn 18:163–171

    Article  CAS  PubMed  Google Scholar 

  • Yamaguchi C, Sakakibara R, Uchiyama T et al (2007) Overactive bladder in diabetes: a peripheral or central mechanism? Neurourol Urodyn 26:807–813

    Article  PubMed  Google Scholar 

  • Yoshimura N, Chancellor MB, Andersson KE et al (2005) Recent advances in understanding the biology of diabetes-associated bladder complications and novel therapy. BJU Int 95:733–738

    Article  PubMed  Google Scholar 

  • Yu HJ, Lee WC, Liu SP, Tai TY, Wu HP, Chen J (2004) Unrecognized voiding difficulty in female type 2 diabetic patients in the diabetes clinic: a prospective case-control study. Diabetes Care 27:988–989

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Division of Urology, Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan

    En Meng MD, DPhil

  2. National Defense Medical Center, Taipei, Taiwan

    En Meng MD, DPhil

  3. Department of Urology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan

    Yao-Chi Chuang MD

Authors
  1. En Meng MD, DPhil
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  2. Yao-Chi Chuang MD
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Correspondence to Yao-Chi Chuang MD .

Editor information

Editors and Affiliations

  1. Department of Urology, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, USA

    Michael B. Chancellor

  2. Department of Urology, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, USA

    Ananias C. Diokno

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© 2016 Springer International Publishing Switzerland

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Meng, E., Chuang, YC. (2016). Diabetes and Other Neurogenic Underactive Bladder Conditions. In: Chancellor, M., Diokno, A. (eds) The Underactive Bladder. Springer, Cham. https://doi.org/10.1007/978-3-319-23687-2_11

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  • DOI: https://doi.org/10.1007/978-3-319-23687-2_11

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-23686-5

  • Online ISBN: 978-3-319-23687-2

  • eBook Packages: MedicineMedicine (R0)

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