Abstract
In 1986, Ernst Ruska was awarded the Nobel Prize in Physics for his pioneering work in the development of the electron microscope. Its diagnostic utility in anatomic pathology has been contested by advanced immunohistochemical and molecular genetic techniques in recent years. The electron microscope still remains a useful tool in selected instances of tumor diagnosis, some nonneoplastic conditions, and renal biopsy interpretation. The main contribution of the electron microscope has been and will continue to be to the understanding of the structure–function relationships at the subcellular level.
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Acknowledgments
The author would like to thank Dr. Moo-Hahm Yum and Mr. Michael P. Goheen for their chapter in the previous edition of this book that served as a model for the current version.
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Olson, J.L. (2016). Diagnostic Electron Microscopy. In: Cheng, L., Bostwick, D. (eds) Essentials of Anatomic Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-23380-2_4
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DOI: https://doi.org/10.1007/978-3-319-23380-2_4
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