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Abstract

With every breath we take, we expose the lungs to a myriad of insults from the outside world. The patterns of injury that result encompass a broad spectrum of neoplastic and nonneoplastic pulmonary diseases. This chapter reviews the salient clinical and pathologic features of these diseases and summarizes special studies, including immunohistochemical, molecular, and genetic tests that may be helpful in diagnosing these diseases.

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Nonneoplastic Lesions

  • American Thoracic Society, European Respiratory Society. American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med. 2002;165:277–304.

    Article  Google Scholar 

  • Farver CF. Sarcoidosis. In: Tomashefski JF, Cagle PT, Farver CF, Fraire AE, editors. Dail and Hammar’s pulmonary pathology. 3rd ed. New York: Springer; 2008. p. 668–964.

    Chapter  Google Scholar 

  • Juvet SC, McCormack FX, Kwiatkowski DJ, Downey GP. Molecular pathogenesis lymphangioleiomyomatosis: lessons learned from orphans. Am J Respir Cell Mol Biol. 2007;36:398–408.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Katzenstein A-LA. Acute lung injury patterns: diffuse alveolar damage and bronchiolitis-obliterans-organizing pneumonia. In: Katzenstein AL, editor. Katzenstein and Askin’s surgical pathology of non-neoplastic lung disease. 4th ed. Philadelphia: W.B. Saunders; 2006. p. 17–44.

    Google Scholar 

  • Katzenstein A-LA, Fiorelli R. Nonspecific interstitial pneumonia/fibrosis. Histologic patterns and clinical significance. Am J Surg Pathol. 1994;18:136.

    Article  CAS  PubMed  Google Scholar 

  • Presneill JJ, Makata K, Inoue Y, Seymour JF. Pulmonary alveolar proteinosis. Clin Chest Med. 2004;25:593–6113.

    Article  PubMed  Google Scholar 

  • Ryu JH, Myers JL, Capizzi SA, Douglas WW, Vassaillo R, Decker PA. Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. Chest. 2005;127:178–84.

    Article  PubMed  Google Scholar 

  • Stewart S, Fishbein MC, Snell GI, et al. Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection. J Heart Lung Transplant. 2007;26:1229–42.

    Article  PubMed  Google Scholar 

  • Stocker JT. Congenital and developmental diseases. In: Tomashefski JF, Cagle PT, Farver CF, Fraire AE, editors. Dail and Hammar’s pulmonary pathology. 3rd ed. New York: Springer; 2008. p. 132–75.

    Chapter  Google Scholar 

  • Travis WD, Colby TC, Koss MN, Rosado-de-Christenson ML, Muller NL, King TEJ. Nonneoplastic disorders of the lower respiratory tract. 1st ed. Washington, DC: The American Registry of Pathology; 2002.

    Google Scholar 

  • Tuder RM, Stacher E, Robinson J, Kumar R, Graham BB. Pathology of pulmonary hypertension. Clin Chst Med. 2013;34:639–50.

    Article  Google Scholar 

Neoplastic Lesions

  • Green FL, Page DL, Fleming ID, et al. AJCC Cancer Staging handbook. 7th ed. New York: Springer; 2010.

    Google Scholar 

  • Husain AN, Colby T, Ordonez N, et al. Guidelines for pathologic diagnosis of malignant mesothelioma: 2012 update of the consensus statement from the international mesothelioma interest group. Arch Pathol Lab Med. 2013;137:647–67.

    Article  PubMed  Google Scholar 

  • Jaffe ES, Lipford Jr EH, Margolick JB, et al. Lymphomatoid granulomatosis and angiocentric lymphoma: a spectrum of post-thymic T-cell proliferations. Semin Respir Med. 1993;10:167–72.

    Article  Google Scholar 

  • Sattler M, Salgia R. Molecular and cellular biology of small cell lung cancer. Semin Oncol. 2003;30:57–71.

    Article  CAS  PubMed  Google Scholar 

  • Sridhar KS, Bounassi MJ, Raub Jr W, Richman SP. Clinical features of adenosquamous lung carcinoma in 127 patients. Am Rev Respir Dis. 1990;142:19–23.

    Article  CAS  PubMed  Google Scholar 

  • Travis WD, Brambilla E, Burke AP, Marx A, Nicholson AG. WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart. Lyon: International Agency for Research on Cancer, 2015.

    Google Scholar 

  • Travis WD, Brambilla E, Noguchi M, et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol. 2011;6:244–85.

    Article  PubMed Central  PubMed  Google Scholar 

  • Travis WD, Brambilla E, Noguchi M, et al. Diagnosis of lung cancer in small biopsies and cytology: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification. Arch Pathol Lab Med. 2013;137:668–84.

    Article  PubMed Central  PubMed  Google Scholar 

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Correspondence to Carol F. Farver MD .

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© 2016 Springer International Publishing Switzerland

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Farver, C.F., Arrossi, A.V. (2016). Lung and Pleura. In: Cheng, L., Bostwick, D. (eds) Essentials of Anatomic Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-23380-2_28

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  • DOI: https://doi.org/10.1007/978-3-319-23380-2_28

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-23379-6

  • Online ISBN: 978-3-319-23380-2

  • eBook Packages: MedicineMedicine (R0)

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