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Sinonasal Melanoma

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Atlas of Sellar and Parasellar Lesions

Abstract

Sinonasal melanoma is a relatively common skull base malignancy that can arise in the nasal cavity (often along the nasal septum) or paranasal sinuses and occasionally primarily in the sphenoid sinus.

The mean age at presentation is 63–67 years.

The most common clinical presentation is epistaxis and airway obstruction.

In rare circumstances, melanoma can arise primarily in the sellar region.

In other rare cases, melanoma can metastasize to the pituitary gland.

Melanoma in this region may cause visual loss, hypopituitarism, headache, and cranial nerve paresis.

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Authors and Affiliations

  1. Department of Neurological Surgery, Keck School of Medicine, University of Southern California, 1200 N State Street, #3300, Los Angeles, CA, 90033, USA

    Gabriel Zada MD, MS

  2. Department of Pathology (Neuropathology), University of Virginia School of Medicine, 1215 Lee Street, Room 3060–HEP, Charlottesville, VA, 22908, USA

    M. Beatriz S. Lopes MD, PhD

  3. Department of Radiology, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA, 02115, USA

    Srinivasan Mukundan Jr. PhD, MD

  4. Department of Neurosurgery, Brigham and Women’s Hospital, 15 Francis Street, Boston, MA, 02115, USA

    Edward Laws Jr. MD

Authors
  1. Gabriel Zada MD, MS
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  2. M. Beatriz S. Lopes MD, PhD
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  3. Srinivasan Mukundan Jr. PhD, MD
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  4. Edward Laws Jr. MD
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Corresponding author

Correspondence to Gabriel Zada MD, MS .

Editor information

Editors and Affiliations

  1. Department of Neurosurgery, University of Southern California, LOS ANGELES, California, USA

    Gabriel Zada

  2. Department of Pathology, University of Virginia, CHARLOTTESVILLE, Virginia, USA

    M. Beatriz S. Lopes

  3. Department of Radiology, Brigham and Women's Hospital, BOSTON, Massachusetts, USA

    Srinivasan Mukundan Jr.

  4. Department of Neurosurgery, Brigham and Women’s Hospital, BOSTON, Massachusetts, USA

    Edward R. Laws Jr.

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Zada, G., Lopes, M.B.S., Mukundan, S., Laws, E. (2016). Sinonasal Melanoma. In: Zada, G., Lopes, M., Mukundan Jr., S., Laws Jr., E. (eds) Atlas of Sellar and Parasellar Lesions. Springer, Cham. https://doi.org/10.1007/978-3-319-22855-6_45

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  • DOI: https://doi.org/10.1007/978-3-319-22855-6_45

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-22854-9

  • Online ISBN: 978-3-319-22855-6

  • eBook Packages: MedicineMedicine (R0)

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