Abstract
This lesion is also called a “cholesterol granuloma.” (See also the next Chap. 24.)
They have been reported to comprise a subset of lesions (up to 34 %) initially thought to be adamantinomatous craniopharyngiomas or Rathke’s cleft cysts.
They are likely to originate from Rathke’s cleft cysts or pituitary adenomas with internal hemorrhage, inflammation, or both.
They tend to occur in younger adult patients (mean, 27 years).
In some patients, the lesion may be part of the Erdheim-Chester disease.
They belong to a spectrum of disease that includes xanthogranulomas, xanthomatous hypophysitis, and xanthogranulomatous hypophysitis. (See “Inflammatory Hypophysitis” in Chap. 56.)
Patients have a relatively high incidence of hypopituitarism and diabetes insipidus.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Paulus W, Honegger J, Keyvani K, Fahlbusch R. Xanthogranuloma of the sellar region: a clinicopathological entity different from adamantinomatous craniopharyngioma. Acta Neuropathol. 1999;97:377–82.
Nishioka H, Shibuya M, Ohtsuka K, Ikeda Y, Haraoka J. Endocrinological and MRI features of pituitary adenomas with marked xanthogranulomatous reaction. Neuroradiology. 2010;52:997–1002.
Reithmeier T, Trost HA, Wolf S, Stolzle A, Feiden W, Lumenta CB. Xanthogranuloma of the Erdheim-Chester type within the sellar region: case report. Clin Neuropathol. 2002;21:24–8.
Burt MG, Morey AL, Turner JJ, Pell M, Sheehy JP, Ho KK. Xanthomatous pituitary lesions: a report of two cases and review of the literature. Pituitary. 2003;6:161–8.
Folkerth RD, Price Jr DL, Schwartz M, Black PM, De Girolami U. Xanthomatous hypophysitis. Am J Surg Pathol. 1998;22:736–41.
Sugata S, Hirano H, Yatsushiro K, Yunoue S, Nakamura K, Arita K. Xanthogranuloma in the suprasellar region. Neurol Med Chir (Tokyo). 2009;49:124–7.
Jung CS, Schanzer A, Hattingen E, Plate KH, Seifert V. Xanthogranuloma of the sellar region. Acta Neurochir (Wien). 2006;148:473–7.
Le BH, Towfighi J, Kapadia SB, Lopes MB. Comparative immunohistochemical assessment of craniopharyngioma and related lesions. Endocr Pathol. 2007;18:23–30.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Zada, G., Lopes, M.B.S., Mukundan, S., Laws, E. (2016). Xanthogranuloma of the Sellar Region. In: Zada, G., Lopes, M., Mukundan Jr., S., Laws Jr., E. (eds) Atlas of Sellar and Parasellar Lesions. Springer, Cham. https://doi.org/10.1007/978-3-319-22855-6_23
Download citation
DOI: https://doi.org/10.1007/978-3-319-22855-6_23
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-22854-9
Online ISBN: 978-3-319-22855-6
eBook Packages: MedicineMedicine (R0)