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Making the Diagnosis: Surgery, a Rational Approach to the Patient with Suspected CBD Stones

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Multidisciplinary Management of Common Bile Duct Stones

Abstract

Common bile duct stones (CBDS) occur frequently in patients with gallstones and often are associated with pain, jaundice, sepsis, pancreatitis, and other potentially serious adverse outcomes. Some CBDS are asymptomatic, and others are occult. Safe and efficient management of CBDS requires a high index of suspicion during the preoperative evaluation, and a logical approach to the diagnostic assessment of symptomatic patients and those at high risk for occult CBDS. Preoperative identification and management of CBDS, in many settings, is superior to intraoperative or postoperative identification. Preoperative identification of CBDS provides maximal benefit for patients by allowing bile duct stones to be removed in advance of surgery, yielding the highest likelihood that laparoscopic cholecystectomy will be performed successfully, maintaining its minimally invasive benefits for patients. However, given the multitude of tests and techniques, the surgeon must coordinate an organized approach to the preoperative diagnosis of CBDS in order to remain cost-efficient. An algorithmic approach is advocated, one that uses noninvasive techniques initially, followed by increasingly invasive approaches to diagnosis and treatment. CBDS that are not detected preoperatively should be identified intraoperatively, when they can be addressed by intraoperative bile duct exploration or the use of adjacent techniques and technologies. It is least desirable for CBDS to be allowed to persist into the postoperative phase, where additional procedures and possible reoperation might be required, or when significant complications could develop related to retained CBDS.

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References

  1. Desai R, Shokouhi BN. Common bile duct stones - their presentation, diagnosis and management. Indian J Surg. 2009;71(5):229–37.

    Article  PubMed  PubMed Central  Google Scholar 

  2. ASGE, Committee SoP, Maple JT, Ben-Menachem T, Anderson MA, Appalaneni V, et al. The role of endoscopy in the evaluation of suspected choledocholithiasis. Gastrointest Endosc. 2010;71(1):1–9.

    Article  Google Scholar 

  3. Nebiker CA, Baierlein SA, Beck S, von Flue M, Ackermann C, Peterli R. Is routine MR cholangiopancreatography (MRCP) justified prior to cholecystectomy? Langenbeck’s Arch Surg. 2009;394(6):1005–10.

    Article  CAS  Google Scholar 

  4. Topal B, Fieuws S, Tomczyk K, Aerts R, Van Steenbergen W, Verslype C, et al. Clinical models are inaccurate in predicting bile duct stones in situ for patients with gallbladder. Surg Endosc. 2009;23(1):38–44.

    Article  PubMed  CAS  Google Scholar 

  5. Borie F, Fingerhut A, Millat B. Acute biliary pancreatitis, endoscopy, and laparoscopy. Surg Endosc. 2003;17(8):1175–80.

    Article  PubMed  CAS  Google Scholar 

  6. Videhult P, Sandblom G, Rudberg C, Rasmussen IC. Are liver function tests, pancreatitis and cholecystitis predictors of common bile duct stones? Results of a prospective, population-based, cohort study of 1171 patients undergoing cholecystectomy. HPB. 2011;13(8):519–27.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Sheen AJ, Asthana S, Al-Mukhtar A, Attia M, Toogood GJ. Preoperative determinants of common bile duct stones during laparoscopic cholecystectomy. Int J Clin Pract. 2008;62(11):1715–9.

    Article  PubMed  CAS  Google Scholar 

  8. Einstein DM, Lapin SA, Ralls PW, Halls JM. The insensitivity of sonography in the detection of choledocholithiasis. AJR Am J Roentgenol. 1984;142:725-8.

    Google Scholar 

  9. Almadi M, Barkun JS, Barkun AN. Management of suspected stones in the common bile duct. CMAJ. 2012;184(8):884–92.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Sakai Y, Tsuyuguchi T, Yukisawa S, Tsuchiya S, Sugiyama H, Miyakawa K, et al. Diagnostic value of magnetic resonance cholangiopancreatography for clinically suspicious spontaneous passage of bile duct stones. J Gastroenterol Hepatol. 2008;23(5):736–40.

    Article  PubMed  Google Scholar 

  11. Peng WK, Sheikh Z, Paterson-Brown S, Nixon SJ. Role of liver function tests in predicting common bile duct stones in acute calculous cholecystitis. Br J Surg. 2005;92(10):1241–7.

    Article  PubMed  CAS  Google Scholar 

  12. Yang MH, Chen TH, Wang SE, Tsai YF, Su CH, Wu CW, et al. Biochemical predictors for absence of common bile duct stones in patients undergoing laparoscopic cholecystectomy. Surg Endosc. 2008;22(7):1620–4.

    Article  PubMed  Google Scholar 

  13. Al-Jiffry BO, Elfateh A, Chundrigar T, Othman B, Almalki O, Rayza F, et al. Non-invasive assessment of choledocholithiasis in patients with gallstones and abnormal liver function. World J Gastroenterol. 2013;19(35):5877–82.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Plaisier PW, van der Hul RL. Surg Endosc 2008;22:1620–1624. Biochemical predictors of common bile duct (CBD) stones. Surg Endosc. 2009;23(4):914. author reply 5.

    Article  PubMed  Google Scholar 

  15. Topal B, Van de Moortel M, Fieuws S, Vanbeckevoort D, Van Steenbergen W, Aerts R, et al. The value of magnetic resonance cholangiopancreatography in predicting common bile duct stones in patients with gallstone disease. Br J Surg. 2003;90(1):42–7.

    Article  PubMed  CAS  Google Scholar 

  16. Rickes S, Treiber G, Monkemuller K, Peitz U, Csepregi A, Kahl S, et al. Impact of the operator’s experience on value of high-resolution transabdominal ultrasound in the diagnosis of choledocholithiasis: a prospective comparison using endoscopic retrograde cholangiography as the gold standard. Scand J Gastroenterol. 2006;41(7):838–43.

    Article  PubMed  Google Scholar 

  17. Grönroos JM, Haapamäki MM, Gullichsen R. Effect of the diameter of the common bile duct on the incidence of bile duct stones in patients with recurrent attacks of right epigastric pain after cholecystectomy. Eur J Surg. 2001;167(10):767–9.

    Article  PubMed  Google Scholar 

  18. Grande M, Torquati A, Tucci G, Rulli F, Adorisio O, Farinon A. Preoperative risk factors for common bile duct stones: defining the patient at high risk in the laparoscopic cholecystectomy era. J Laparoendosc Adv Surg Tech A. 2004;14(5):281–6.

    Article  PubMed  Google Scholar 

  19. Karincaoglu M, Yildirim B, Seckin Y, Kantarceken B, Aladag M, Hilmioglu F. Common bile duct diameters after endoscopic sphincterotomy in patients with common bile duct stones: ultrasonographic evaluation. Abdom Imaging. 2003;28(4):531–5.

    Article  PubMed  CAS  Google Scholar 

  20. Tseng CW, Chen CC, Chen TS, Chang FY, Lin HC, Lee SD. Can computed tomography with coronal reconstruction improve the diagnosis of choledocholithiasis? J Gastroenterol Hepatol. 2008;23(10):1586–9.

    Article  PubMed  Google Scholar 

  21. Lee JK, Kim TK, Byun JH, Kim AY, Ha HK, Kim PN, et al. Diagnosis of intrahepatic and common duct stones: combined unenhanced and contrast-enhanced helical CT in 1090 patients. Abdom Imaging. 2006;31(4):425–32.

    Article  PubMed  Google Scholar 

  22. Soto JA, Alvarez O, Múnera F, Velez SM, Valencia J, Ramírez N. Diagnosing bile duct stones. Am J Roentgenol. 2000;175(4):1127–34.

    Article  CAS  Google Scholar 

  23. Boraschi P, Giqoni R, Braccini G, Lamacchia M, Rossi M, Falaschi F. Detection of common bile duct stones before laparoscopic cholecystectomy. Acta Radiol. 2002;43(6):593–8.

    Article  PubMed  CAS  Google Scholar 

  24. Raval B, Kramer L. Advances in the imaging of common duct stones using magnetic resonance cholangiography, endoscopic ultrasonography, and laparoscopic ultrasonography. Semin Laparosc Surg. 2000;7(4):232–6.

    Article  PubMed  CAS  Google Scholar 

  25. Stiris M, Tennøe B, Aadland E, Lunde OC. Cholangiopancreaticography and endoscopic retrograde cholangiopancreaticography in patients with suspected common bile duct stones. Acta Radiol. 2000;41:269–72.

    Article  PubMed  CAS  Google Scholar 

  26. Kejriwal R, Liang J, Andrewson G, Hill A. Magnetic resonance imaging of the common bile duct to exclude choledocholithiasis. ANZ J Surg. 2004;74(8):619–21.

    Article  PubMed  Google Scholar 

  27. Schmidt S, Chevallier P, Novellas S, Gelsi E, Vanbiervliet G, Tran A, Schnyder P, Bruneton JN. Choledocholithiasis: repetitive thick-slab single-shot projection magnetic resonance cholangiopancreaticography versus endoscopic ultrasonography. Eur Radiol. 2007;17(1):241–50.

    Article  PubMed  CAS  Google Scholar 

  28. Mendler MH, Bouillet P, Sautereau D, Chaumerliac P, Cessot F, Le Sidaner A, et al. Value of MR cholangiography in the diagnosis of obstructive diseases of the biliary tree: a study of 58 cases. Am J Gastroenterol. 1998;93(12):2482–90.

    Article  PubMed  CAS  Google Scholar 

  29. Sharma SK, Larson KA, Adler Z, Goldfarb MA. Role of endoscopic retrograde cholangiopancreatography in the management of suspected choledocholithiasis. Surg Endosc. 2003;17(6):868–71.

    Article  PubMed  CAS  Google Scholar 

  30. Kubota Y, Takaoka M, Yamamoto S, Shibatani N, Shimatani M, Takamido S, et al. Diagnosis of common bile duct calculi with intraductal ultrasonography during endoscopic biliary cannulation. J Gastroenterol Hepatol. 2002;17(6):708–12.

    Article  PubMed  Google Scholar 

  31. Urbach DR, Khajanchee YS, Jobe BA, Standage BA, Hansen PD, Swanstrom LL. Cost-effective management of common bile duct stones: a decision analysis of the use of endoscopic retrograde cholangiopancreatography (ERCP), intraoperative cholangiography, and laparoscopic bile duct exploration. Surg Endosc. 2001;15(1):4–13.

    Article  PubMed  CAS  Google Scholar 

  32. Fanelli RD, Gersin KS. Laparoscopic endobiliary stenting: a simplified approach to the management of occult common bile duct stones. J Gastrointest Surg. 2001;5(1):74–80.

    Article  PubMed  CAS  Google Scholar 

  33. Fanelli RD, Gersin KS, Mainella MT. Laparoscopic endobiliary stenting significantly improves success of postoperative endoscopic retrograde cholangiopancreatography in low-volume centers. Surg Endosc. 2002;16(3):487–91.

    Article  PubMed  CAS  Google Scholar 

  34. Gersin KS, Fanelli RD. Laparoscopic endobiliary stenting as an adjunct to common bile duct exploration. Surg Endosc. 1998;12(4):301–4.

    Article  PubMed  CAS  Google Scholar 

  35. Petelin JB. Laparoscopic common bile duct exploration. Surg Endosc. 2003;17(11):1705–15.

    Article  PubMed  CAS  Google Scholar 

  36. Petrov MS, Savides TJ. Systematic review of endoscopic ultrasonography versus endoscopic retrograde cholangiopancreatography for suspected choledocholithiasis. Br J Surg. 2009;96(9):967–74.

    Article  PubMed  CAS  Google Scholar 

  37. Patel AP, Lokey JS, Harris JB, Sticca RP, McGill ES, Arrillaga A, Miller RS, Kopelman TR. Current management of common bile duct stones in a teaching community hospital. Am Surg. 2003;69(7):555–60.

    PubMed  Google Scholar 

  38. Aljebreen A, Azzam N, Eloubeidi MA. Prospective study of endoscopic ultrasound performance in suspected choledocholithiasis. J Gastroenterol Hepatol. 2008;23(5):741–5.

    Article  PubMed  Google Scholar 

  39. Ang TL, Teo EK, Fock KM. Endosonography- vs. endoscopic retrograde cholangiopancreatography-based strategies in the evaluation of suspected common bile duct stones in patients with normal transabdominal imaging. Aliment Pharmacol Ther. 2007;26(8):1163–70.

    Article  PubMed  CAS  Google Scholar 

  40. Lee YT, Chan FKL, Leung WK, Chan HLY, Wu JCY, Yung MY, et al. Comparison of EUS and ERCP in the investigation with suspected biliary obstruction caused by choledocholithiasis: a randomized study. Gastrointest Endosc. 2008;67(4):660–8.

    Article  PubMed  Google Scholar 

  41. Tseng LJ, Jao YT, Mo LR, Lin RC. Over-the-wire US catheter probe as an adjunct to ERCP in the detection of choledocholithiasis. Gastrointest Endosc. 2001;54(6):720–3.

    Article  PubMed  CAS  Google Scholar 

  42. Das A, Isenberg G, Wong RC, Sivak Jr MV, Chak A. Wire-guided intraductal US: an adjunct to ERCP in the management of bile duct stones. Gastrointest Endosc. 2001;54(1):31–6.

    Article  PubMed  CAS  Google Scholar 

  43. Shah A, Gilmour J, Bransom C, Jones R, Blackett R. Routine on-table cholangiography during laparoscopic cholecystectomy is well worthwhile. Internet J Surg. 2006;12(1):1–4.

    Google Scholar 

  44. Rothlin MA, Schlumpf R, Largiader F. Laparoscopic sonography. An alternative to routine intraoperative cholangiography? Arch Surg (Chicago, IL: 1960). 1994;129(7):694–700.

    CAS  Google Scholar 

  45. Catheline J, Rizk N, Champault G. A comparison of laparoscopic ultrasound versus cholangiography in the evaluation of the biliary tree during laparoscopic cholecystectomy. Eur J Ultrasound. 1999;10(1):1–9.

    Article  PubMed  CAS  Google Scholar 

  46. Fanelli RD. The likelihood of predicting the presence of CBD stones. Presentation given at the 2014 the Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting. CBD Stones Postgraduate Course. 2014. http://www.sages.org/video/likelihood-predicting-presence-cbd-stones/. Accessed 4 Sep 2014.

  47. Dalton SJ, Balupuri S, Guest J. Routine magnetic resonance cholangiopancreatography and intra-operative cholangiogram in the evaluation of common bile duct stones. Ann R Coll Surg Engl. 2005;87(6):469–70.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  48. Horwood J, Akbar F, Davis K, Morgan R. Prospective evaluation of a selective approach to cholangiography for suspected common bile duct stones. Ann R Coll Surg Engl. 2010;92(3):206–10.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Flum DR, Flowers C, Veenstra DL. A cost-effectiveness analysis of intraoperative cholangiography in the prevention of bile duct injury during laparoscopic cholecystectomy. J Am Coll Surg. 2003;196(3):385–93.

    Article  PubMed  Google Scholar 

  50. Machi J, Tateishi T, Oishi AJ, Furumoto NL, Oishi RH, Uchida S, et al. Laparoscopic ultrasonography versus operative cholangiography during laparoscopic cholecystectomy: review of the literature and a comparison with open intraoperative ultrasonography. J Am Coll Surg. 1999;188(4):360–7.

    Article  PubMed  CAS  Google Scholar 

  51. Pucher PH, Brunt LM, Fanelli RD, Asbun HJ, Aggarwal R. SAGES expert Delphi consensus: critical factors for safe surgical practice in laparoscopic cholecystectomy. Surg Endosc. 11 Feb 2015. [Epub ahead of print].

    Google Scholar 

  52. Tranter SE, Thompson MH. Potential of laparoscopic ultrasonography as an alternative to operative cholangiography in the detection of bile duct stones. Br J Surg. 2001;88(1):65–9.

    Article  PubMed  CAS  Google Scholar 

  53. Tsitouridis I, Lazaraki G, Papastergiou C, Pagalos E, Germanidis G. Low conjunction of the cystic duct with the common bile duct: does it correlate with the formation of common bile duct stones? Surg Endosc. 2007;21(1):48–52.

    Article  PubMed  CAS  Google Scholar 

  54. Strnad P, von Figura G, Gruss R, Jareis KM, Stiehl A, Kulaksiz H. Oblique bile duct predisposes to the recurrence of bile duct stones. PLoS One. 2013;8(1):e54601.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  55. Kim CW, Chang JH, Kim JH, Kim TH, Lee IS, Han SW. Size and type of periampullary duodenal diverticula are associated with bile duct diameter and recurrence of bile duct stones. J Gastroenterol Hepatol. 2013;28(5):893–8.

    Article  PubMed  Google Scholar 

  56. Sarli L, Costi R, Gobbi S, Iusco D, Sgobba G, Roncoroni L. Scoring system to predict asymptomatic choledocholithiasis before laparoscopic cholecystectomy. A matched case-control study. Surg Endosc. 2003;17(9):1396–403.

    Article  PubMed  CAS  Google Scholar 

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Fanelli, R.D., Andrew, B.D. (2016). Making the Diagnosis: Surgery, a Rational Approach to the Patient with Suspected CBD Stones. In: Hazey, J., Conwell, D., Guy, G. (eds) Multidisciplinary Management of Common Bile Duct Stones. Springer, Cham. https://doi.org/10.1007/978-3-319-22765-8_5

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  • DOI: https://doi.org/10.1007/978-3-319-22765-8_5

  • Publisher Name: Springer, Cham

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