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Pediatric Melanoma and Atypical Melanocytic Neoplasms

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Melanoma

Part of the book series: Cancer Treatment and Research ((CTAR,volume 167))

Abstract

Melanoma is uncommon in the pediatric age range, but is increasing in frequency and often presents with atypical features compared to the classic ABCDE criteria common to adult melanoma cases. Moreover, many melanocytic neoplasms in childhood pose diagnostic challenges to the pathologist, and sometimes cannot be unequivocally classified as benign nevi or melanoma. This chapter addresses the evaluation and management of pediatric patients with melanoma and atypical melanocytic neoplasms, including the roles of and unresolved questions surrounding sentinel lymph node biopsy, completion lymphadenectomy, adjuvant therapy, and treatment of advanced disease.

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Authors and Affiliations

  1. Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA

    Radhika Sreeraman Kumar

  2. Department of Anatomic Pathology, Moffitt Cancer Center, Tampa, FL, USA

    Jane L. Messina

  3. Department of Cutaneous Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA

    Jane L. Messina, Damon Reed & Vernon K. Sondak

  4. Department of Pathology and Cell Biology, University of South Florida Morsani College of Medicine, Tampa, FL, USA

    Jane L. Messina

  5. Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA

    Damon Reed

  6. Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN, USA

    Fariba Navid

  7. Department of Oncologic Sciences and Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA

    Vernon K. Sondak

  8. Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA

    Jane L. Messina

  9. Department of Dermatology, University of South Florida Morsani College of Medicine, Tampa, FL, USA

    Jane L. Messina

  10. Adolescent and Young Adult (AYA) Program, Sarcoma Department, Moffitt Cancer Center, Tampa, FL, USA

    Damon Reed

  11. Department of Hematology/Oncology , All Children’s Hospital Johns Hopkins Medicine , St. Petersburg, FL, USA

    Damon Reed

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  1. Radhika Sreeraman Kumar
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  2. Jane L. Messina
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  3. Damon Reed
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  4. Fariba Navid
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  5. Vernon K. Sondak
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Correspondence to Vernon K. Sondak .

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  1. Rutgers Cancer Institute of New Jersey, New Brunswick, New York, USA

    Howard L. Kaufman

  2. Robert Wood Johnson Medical School, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA

    Janice M. Mehnert

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Sreeraman Kumar, R., Messina, J.L., Reed, D., Navid, F., Sondak, V.K. (2016). Pediatric Melanoma and Atypical Melanocytic Neoplasms. In: Kaufman, H., Mehnert, J. (eds) Melanoma. Cancer Treatment and Research, vol 167. Springer, Cham. https://doi.org/10.1007/978-3-319-22539-5_15

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