Skip to main content

Paraneoplastic Retinopathy

  • Chapter
  • First Online:
Manual of Retinal Diseases
  • 110 Accesses

Abstract

Paraneoplastic retinopathy is a syndrome where one’s immune system response to a tumor leads to generation of antibodies to the tumor antigen that cross-reacts with retinal proteins. These autoantibodies to the retina lead to rod and cone photoreceptor dysfunction. There are several classifications of paraneoplastic retinopathies; we discuss the three most common types carcinoma-associated retinopathy, melanoma-associated retinopathy, and bilateral diffuse uveal melanocytic proliferation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 199.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References and Suggested Reading

  1. Hecklenlively JR, Ferreyra HA. Autoimmune retinopathy: a review and summary. Semin Immunopathol. 2008;30:127–34.

    Article  Google Scholar 

  2. Keltner JL, Roth AM, Chang S. Photoreceptor degeneration – a possible autoimmune disease. Arch Ophthalmol. 1983;101:564–9.

    Article  CAS  PubMed  Google Scholar 

  3. Ferreyra HA, Jayasundera T, Kahn NW, et al. Management of autoimmune retinopathies with immunosuppression. Arch Ophthalmol. 2009;127(4):390–7.

    Article  CAS  PubMed  Google Scholar 

  4. Chan JW. Paraneoplastic retinopathies and optic neuropathies. Surv Ophthalmol. 2003;48(1):12–38.

    Article  PubMed  Google Scholar 

  5. Courtney RJ, Singh RP, Aronow MB, Singh AD. Ocular paraneoplastic diseases. In: Singh AD, Damato BE, editors. Retinal tumors. Clinical ophthalmic oncology. Heidelberg: Springer; 2015. p. 133–52.

    Google Scholar 

  6. Singh AD, Rundle PA, Slater DN, et al. Uveal and cutaneous involvement in paraneoplastic melanocytic proliferation. Arch Ophthalmol. 2003;121(11):1637–40.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Veeral S. Shah MD, PhD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Shah, V.S. (2016). Paraneoplastic Retinopathy. In: Medina, C., Townsend, J., Singh, A. (eds) Manual of Retinal Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-20460-4_28

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-20460-4_28

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-20459-8

  • Online ISBN: 978-3-319-20460-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics