Skip to main content

Invasive Management in CAD Patients with Stage 4 Renal Dysfunction or on Dialysis

  • Chapter
Controversies in Cardiology

Abstract

Chronic kidney disease (CKD) is an independent risk factor for coronary artery disease (CAD), and is associated with more complex coronary pathologies such as multivessel disease and left main involvement. Greater reductions in renal function are associated with increasingly poor outcomes following revascularization therapy. The optimal revascularization approach for obstructive CAD in stable or unstable coronary syndromes in CKD has not been defined as there is a lack of sufficiently powered randomized data in this patient subset. While coronary artery bypass grafting (CABG) appears to be associated with better long-term survival and less long-term ischemic events than percutaneous coronary intervention (PCI), the choice of revascularization therapy should be individualized, taking into account patient co-morbidities, functional status, and preference.

Disclosures

All authors declare no conflict of interest.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation. 2003;108(17):2154–69.

    Article  PubMed  Google Scholar 

  2. Chen J, Muntner P, Hamm LL, Jones DW, Batuman V, Fonseca V, et al. The metabolic syndrome and chronic kidney disease in U.S. adults. Ann Intern Med. 2004;140(3):167–74.

    Article  PubMed  Google Scholar 

  3. Ix JH, Shlipak MG, Liu HH, Schiller NB, Whooley MA. Association between renal insufficiency and inducible ischemia in patients with coronary artery disease: the heart and soul study. J Am Soc Nephrol: JASN. 2003;14(12):3233–8.

    Article  PubMed Central  PubMed  Google Scholar 

  4. Wright RS, Reeder GS, Herzog CA, Albright RC, Williams BA, Dvorak DL, et al. Acute myocardial infarction and renal dysfunction: a high-risk combination. Ann Intern Med. 2002;137(7):563–70.

    Article  PubMed  Google Scholar 

  5. Collins AJ, Foley RN, Chavers B, Gilbertson D, Herzog C, Johansen K, et al. ‘United States Renal Data System 2011 Annual Data Report: Atlas of chronic kidney disease & end-stage renal disease in the United States. Am J Kidney Dis Off J Natl Kidney Found. 2012;59(1 Suppl 1):A7. e1–420.

    Article  Google Scholar 

  6. Herzog CA. How to manage the renal patient with coronary heart disease: the agony and the ecstasy of opinion-based medicine. J Am Soc Nephrol: JASN. 2003;14(10):2556–72.

    Article  PubMed  Google Scholar 

  7. Longenecker JC, Coresh J, Powe NR, Levey AS, Fink NE, Martin A, et al. Traditional cardiovascular disease risk factors in dialysis patients compared with the general population: the CHOICE Study. J Am Soc Nephrol. 2002;13(7):1918–27.

    Article  PubMed  Google Scholar 

  8. Shroff GR, Solid CA, Herzog CA. Long-term survival and repeat coronary revascularization in dialysis patients after surgical and percutaneous coronary revascularization with drug-eluting and bare metal stents in the United States. Circulation (New York, NY). 2013;127(18):1861–9.

    Google Scholar 

  9. Tadros GM, Herzog CA. Percutaneous coronary intervention in chronic kidney disease patients. J Nephrol. 2004;17(3):364–8.

    PubMed  Google Scholar 

  10. Coca SG, Krumholz HM, Garg AX, Parikh CR. Underrepresentation of renal disease in randomized controlled trials of cardiovascular disease. JAMA. 2006;296(11):1377–84.

    Article  CAS  PubMed  Google Scholar 

  11. McCullough PA. Cardiorenal risk: an important clinical intersection. Rev Cardiovasc Med. 2002;3(2):71–6.

    PubMed  Google Scholar 

  12. Manjunath G, Tighiouart H, Ibrahim H, MacLeod B, Salem DN, Griffith JL, et al. Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes in the community. J Am Coll Cardiol. 2003;41(1):47–55.

    Article  PubMed  Google Scholar 

  13. Baber U, Stone GW, Weisz G, Moreno P, Dangas G, Maehara A, et al. Coronary plaque composition, morphology, and outcomes in patients with and without chronic kidney disease presenting with acute coronary syndromes. JACC Cardiovasc Imaging. 2012;5(3 Suppl):S53–61.

    Article  PubMed  Google Scholar 

  14. Charytan D, Kuntz RE, Mauri L, DeFilippi C. Distribution of coronary artery disease and relation to mortality in asymptomatic hemodialysis patients. Am J Kidney Dis. 2007;49(3):409–16.

    Article  PubMed  Google Scholar 

  15. Joki N, Hase H, Takahashi Y, Ishikawa H, Nakamura R, Imamura Y, et al. Angiographical severity of coronary atherosclerosis predicts death in the first year of hemodialysis. Int Urol Nephrol. 2003;35(2):289–97.

    Article  PubMed  Google Scholar 

  16. Wizemann V. Coronary artery disease in dialysis patients. Nephron. 1996;74(4):642–51.

    Article  CAS  PubMed  Google Scholar 

  17. Lindner A, Charra B, Sherrard DJ, Scribner BH. Accelerated atherosclerosis in prolonged maintenance hemodialysis. N Engl J Med. 1974;290(13):697–701.

    Article  CAS  PubMed  Google Scholar 

  18. Cheung AK, Sarnak MJ, Yan G, Berkoben M, Heyka R, Kaufman A, et al. Cardiac diseases in maintenance hemodialysis patients: results of the HEMO Study. Kidney Int. 2004;65(6):2380–9.

    Article  PubMed  Google Scholar 

  19. Joki N, Hase H, Nakamura R, Yamaguchi T. Onset of coronary artery disease prior to initiation of haemodialysis in patients with end-stage renal disease. Nephrol Dial Transpl Off Publ Eur Dial Transplant Assoc – Eur Renal Assoc. 1997;12(4):718–23.

    CAS  Google Scholar 

  20. Foley RN, Herzog CA, Collins AJ. Blood pressure and long-term mortality in United States hemodialysis patients: USRDS Waves 3 and 4 Study. Kidney Int. 2002;62(5):1784–90.

    Article  PubMed  Google Scholar 

  21. Di Benedetto A, Marcelli D, D’Andrea A, Cice G, D’Isa S, Cappabianca F, et al. Risk factors and underlying cardiovascular diseases in incident ESRD patients. J Nephrol. 2005;18(5):592–8.

    PubMed  Google Scholar 

  22. Aggarwal A, Kabbani SS, Rimmer JM, Gennari FJ, Taatjes DJ, Sobel BE, et al. Biphasic effects of hemodialysis on platelet reactivity in patients with end-stage renal disease: a potential contributor to cardiovascular risk. Am J Kidney Dis. 2002;40(2):315–22.

    Article  PubMed  Google Scholar 

  23. Sreedhara R, Itagaki I, Lynn B, Hakim RM. Defective platelet aggregation in uremia is transiently worsened by hemodialysis. Am J Kidney Dis Off J Natl Kidney Found. 1995;25(4):555–63.

    Article  CAS  Google Scholar 

  24. Schindler R, Boenisch O, Fischer C, Frei U. Effect of the hemodialysis membrane on the inflammatory reaction in vivo. Clin Nephrol. 2000;53(6):452–9.

    CAS  PubMed  Google Scholar 

  25. Weigert AL, Schafer AI. Uremic bleeding: pathogenesis and therapy. Am J Med Sci. 1998;316(2):94–104.

    Article  CAS  PubMed  Google Scholar 

  26. Raine AE, Margreiter R, Brunner FP, Ehrich JH, Geerlings W, Landais P, et al. Report on management of renal failure in Europe, XXII, 1991. Nephrol Dial Transpl Off Publ Eur Dial Transplant Assoc – Eur Renal Assoc. 1992;7 Suppl 2:7–35.

    Google Scholar 

  27. Aronow WS, Ahn C, Mercando AD, Epstein S. Prognostic significance of silent ischemia in elderly patients with peripheral arterial disease with and without previous myocardial infarction. Am J Cardiol. 1992;69(1):137–9.

    Article  CAS  PubMed  Google Scholar 

  28. Bansal N. Clinically silent myocardial infarctions in the CKD community. Nephrol Dial Transplant. 2012;27(9):3387–91.

    Article  PubMed  Google Scholar 

  29. Nesto RW, Watson FS, Kowalchuk GJ, Zarich SW, Hill T, Lewis SM, et al. Silent myocardial ischemia and infarction in diabetics with peripheral vascular disease: assessment by dipyridamole thallium-201 scintigraphy. Am Heart J. 1990;120(5):1073–7.

    Article  CAS  PubMed  Google Scholar 

  30. Surana SP, Riella LV, Keithi-Reddy SR, Charytan DM, Singh AK. Acute coronary syndrome in ESRD patients. Kidney Int. 2009;75(5):558–62.

    Article  PubMed  Google Scholar 

  31. K/DOQI Workgroup. K/DOQI clinical practice guidelines for cardiovascular disease in dialysis patients. Am J Kidney Dis. 2005;45(4 Suppl 3):16–153.

    Google Scholar 

  32. Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, et al. 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. Circulation. 2011;124(23):2574–609.

    Article  PubMed  Google Scholar 

  33. Serruys PW, Morice M-C, Kappetein AP, Colombo A, Holmes DR, Mack MJ, et al. Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N Engl J Med. 2009;360(10):961–72.

    Article  CAS  PubMed  Google Scholar 

  34. Zheng H, Xue S, Lian F, Huang R-t, Z-I H, Wang Y-Y. Meta-analysis of clinical studies comparing coronary artery bypass grafting with percutaneous coronary intervention in patients with end-stage renal disease. Eur J Cardiothorac Surg. 2013;43(3):459–67.

    Article  PubMed  Google Scholar 

  35. Ix JH, Mercado N, Shlipak MG, Lemos PA, Boersma E, Lindeboom W, et al. Association of chronic kidney disease with clinical outcomes after coronary revascularization: the Arterial Revascularization Therapies Study (ARTS). Am Heart J. 2005;149(3):512–9.

    Article  PubMed  Google Scholar 

  36. Herzog CA, Ma JZ, Collins AJ. Comparative survival of dialysis patients in the United States after coronary angioplasty, coronary artery stenting, and coronary artery bypass surgery and impact of diabetes. Circulation. 2002;106(17):2207–11.

    Article  PubMed  Google Scholar 

  37. Agirbasli M, Weintraub WS, Chang GL, King SB, Guyton RA, Thompson TD, et al. Outcome of coronary revascularization in patients on renal dialysis. Am J Cardiol. 2000;86(4):395–9.

    Article  CAS  PubMed  Google Scholar 

  38. Hemmelgarn BR. Survival after coronary revascularization among patients with kidney disease. Circulation (New York, NY). 2004;110(14):1890–5.

    Google Scholar 

  39. Rinehart AL. A comparison of coronary angioplasty and coronary artery bypass grafting outcomes in chronic dialysis patients. Am J Kidney Dis. 1995;25(2):281–90.

    Article  CAS  PubMed  Google Scholar 

  40. Ohmoto Y, Ayabe M, Hara K, Sugimoto T, Tagawa H, Fukuda S, et al. Long-term outcome of percutaneous transluminal coronary angioplasty and coronary artery bypass grafting in patients with end-stage renal disease. Jpn Circ J. 1999;63(12):981–7.

    Article  CAS  PubMed  Google Scholar 

  41. Nevis IF, Mathew A, Novick RJ, Parikh CR, Devereaux PJ, Natarajan MK, et al. Optimal method of coronary revascularization in patients receiving dialysis: systematic review. Clin J Am Soc Nephrol. 2009;4(2):369–78.

    PubMed Central  PubMed  Google Scholar 

  42. Kannan A, Poongkunran C, Medina R, Ramanujam V, Poongkunran M, Balamuthusamy S. Coronary revascularization in chronic and end-stage renal disease: a systematic review and meta-analysis. Am J Ther. 2014.

    Google Scholar 

  43. Marui A, Kimura T, Nishiwaki N, Mitsudo K, Komiya T, Hanyu M, et al. Percutaneous coronary intervention versus coronary artery bypass grafting in patients with end-stage renal disease requiring dialysis (5-year outcomes of the CREDO-Kyoto PCI/CABG Registry Cohort-2). Am J Cardiol. 2014;114(4):555–61.

    Article  PubMed  Google Scholar 

  44. King 3rd SB, Marshall JJ, Tummala PE. Revascularization for coronary artery disease: stents versus bypass surgery. Annu Rev Med. 2010;61:199–213.

    Article  CAS  PubMed  Google Scholar 

  45. Kar S, Coats W, Aggarwal K. Percutaneous coronary intervention versus coronary artery bypass graft in chronic kidney disease: optimal treatment options. Hemodial Int Int Symp Home Hemodial. 2011;15 Suppl 1:S30–6.

    Article  Google Scholar 

  46. Anderson RJ, O’Brien M, MaWhinney S, VillaNueva CB, Moritz TE, Sethi GK, et al. Renal failure predisposes patients to adverse outcome after coronary artery bypass surgery. VA Cooperative Study #5. Kidney Int. 1999;55(3):1057–62.

    Article  CAS  PubMed  Google Scholar 

  47. Cooper WA, O’Brien SM, Thourani VH, Guyton RA, Bridges CR, Szczech LA, et al. Impact of renal dysfunction on outcomes of coronary artery bypass surgery: results from the Society of Thoracic Surgeons National Adult Cardiac Database. Circulation. 2006;113(8):1063–70.

    Article  PubMed  Google Scholar 

  48. Gibbons RJ, Fihn SD. Coronary revascularization: new evidence, new challenges. Ann Intern Med. 2007;147(10):732–4.

    Article  PubMed  Google Scholar 

  49. Deo SV, Shah IK, Dunlay SM, Erwin PJ, Dillon JM, Park SJ. Myocardial revascularisation in renal dysfunction: a systematic review and meta-analysis. Heart Lung Circ. 2013;22(10):827–35.

    Article  PubMed  Google Scholar 

  50. Herzog CA, Ma JZ, Collins AJ. Long-term outcome of dialysis patients in the United States with coronary revascularization procedures. Kidney Int. 1999;56(1):324–32.

    Article  CAS  PubMed  Google Scholar 

  51. Herzog CA, Ma JZ, Collins AJ. Poor long-term survival after acute myocardial infarction among patients on long-term dialysis. N Engl J Med. 1998;339(12):799–805.

    Article  CAS  PubMed  Google Scholar 

  52. Bassand JP, Hamm CW, Ardissino D, Boersma E, Budaj A, Fernandez-Aviles F, et al. Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes. Eur Heart J. 2007;28(13):1598–660.

    Article  CAS  PubMed  Google Scholar 

  53. Szummer K, Lundman P, Jacobson SH, Schon S, Lindback J, Stenestrand U, et al. Influence of renal function on the effects of early revascularization in non-ST-elevation myocardial infarction: data from the Swedish Web-System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies (SWEDEHEART). Circulation. 2009;120(10):851–8.

    Article  CAS  PubMed  Google Scholar 

  54. Amsterdam EA, Wenger NK, Brindis RG, Casey DE, Ganiats TG, Holmes DR, et al. 2014 AHA/ACC Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;130(25):2354–94.

    Article  PubMed  Google Scholar 

  55. Januzzi JL, Cannon CP, DiBattiste PM, Murphy S, Weintraub W, Braunwald E. Effects of renal insufficiency on early invasive management in patients with acute coronary syndromes (The TACTICS-TIMI 18 Trial). Am J Cardiol. 2002;90(11):1246–9.

    Article  PubMed  Google Scholar 

  56. Lagerqvist B, Husted S, Kontny F, Stahle E, Swahn E, Wallentin L. 5-year outcomes in the FRISC-II randomised trial of an invasive versus a non-invasive strategy in non-ST-elevation acute coronary syndrome: a follow-up study. Lancet. 2006;368(9540):998–1004.

    Article  PubMed  Google Scholar 

  57. Damman P, Hirsch A, Windhausen F, Tijssen JGP, de Winter RJ. 5-year clinical outcomes in the ICTUS (Invasive versus Conservative Treatment in Unstable coronary Syndromes) Trial a randomized comparison of an early invasive versus selective invasive management in patients with non–ST-segment elevation acute coronary syndrome. J Am Coll Cardiol. 2010;55(9):858–64.

    Article  PubMed  Google Scholar 

  58. Woudstra P, Damman P, Clayton T, Wallentin L, Lagerqvist B, Fox K, et al. Routine invasive versus selective invasive strategy and long-term outcomes in patients with reduced renal function presenting with non-ST-segment elevation acute coronary syndrome. J Am Coll Cardiol. 2012;59(13 Suppl 1):E392–E.

    Google Scholar 

  59. Santopinto JJ, Fox KAA, Goldberg RJ, Budaj A, Piñero G, Avezum A, et al. Creatinine clearance and adverse hospital outcomes in patients with acute coronary syndromes: findings from the global registry of acute coronary events (GRACE). Heart. 2003;89(9):1003–8.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  60. Anavekar NS, McMurray JJV, Velazquez EJ, Solomon SD, Kober L, Rouleau J-L, et al. Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction. N Engl J Med. 2004;351(13):1285–95.

    Article  CAS  PubMed  Google Scholar 

  61. Rihal CS, Textor SC, Grill DE, Berger PB, Ting HH, Best PJ, et al. Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention. Circulation. 2002;105(19):2259–64.

    Article  PubMed  Google Scholar 

  62. Chen Y-Y, Wang J-F, Zhang Y-J, Xie S-L, Nie R-Q. Optimal strategy of coronary revascularization in chronic kidney disease patients: a meta-analysis. Eur J Intern Med. 2013;24(4):354–61.

    Article  PubMed  Google Scholar 

  63. Best PJM, Lennon R, Ting HH, Bell MR, Rihal CS, Holmes Jr DR, et al. The impact of renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary interventions. J Am Coll Cardiol. 2002;39(7):1113–9.

    Article  PubMed  Google Scholar 

  64. Reddan DN, Szczech LA, Tuttle RH, Shaw LK, Jones RH, Schwab SJ, et al. Chronic kidney disease, mortality, and treatment strategies among patients with clinically significant coronary artery disease. J Am Soc Nephrol: JASN. 2003;14(9):2373–80.

    Article  PubMed  Google Scholar 

  65. Best PJ, Berger PB, Davis BR, Grines CL, Sadeghi HM, Williams BA, et al. Impact of mild or moderate chronic kidney disease on the frequency of restenosis: results from the PRESTO trial. J Am Coll Cardiol. 2004;44(9):1786–91.

    PubMed  Google Scholar 

  66. Osten MD, Ivanov J, Eichhofer J, Seidelin PH, Ross JR, Barolet A, et al. Impact of renal insufficiency on angiographic, procedural, and in-hospital outcomes following percutaneous coronary intervention. Am J Cardiol. 2008;101(6):780–5.

    Article  PubMed  Google Scholar 

  67. El-Menyar AA, Al Suwaidi J, Holmes Jr DR. Use of drug-eluting stents in patients with coronary artery disease and renal insufficiency. Mayo Clin Proc. 2010;85(2):165–71.

    Article  PubMed Central  PubMed  Google Scholar 

  68. Krotin M, Vukovic D, Stojanovic O, Milovanovic B, Celeketic D, Blagojevic R. Prognostic value of dobutamine stress echocardiography in patients with terminal renal insufficiency undergoing hemodialysis--a 5-year follow up. Med Pregl. 2007;60(7–8):333–7.

    Article  PubMed  Google Scholar 

  69. Francis GS, Sharma B, Collins AL, Helseth HK, Comty CM. Coronary-artery surgery in patients with end-stage renal disease. Ann Intern Med. 1980;92(4):499–503.

    Article  CAS  PubMed  Google Scholar 

  70. Gruberg L, Dangas G, Mehran R, Mintz GS, Kent KM, Pichard AD, et al. Clinical outcome following percutaneous coronary interventions in patients with chronic renal failure. Catheter Cardiovasc Interv Off J Soc Card Angiogr Interv. 2002;55(1):66–72.

    Article  Google Scholar 

  71. Tsutsui M, Shimokawa H, Tanaka S, Yoshihara S, Higuchi S, Matsuguchi T, et al. Granulocyte activation in restenosis after percutaneous transluminal coronary angioplasty. Jpn Circ J. 1996;60(1):27–34.

    Article  CAS  PubMed  Google Scholar 

  72. Mehran R, Aymong ED, Nikolsky E, Lasic Z, Iakovou I, Fahy M, et al. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol. 2004;44(7):1393–9.

    PubMed  Google Scholar 

  73. Athappan G, Ponniah T. Clinical outcomes of dialysis patients after implantation of DES: meta analysis and systematic review of literature. Minerva Cardioangiol. 2009;57(3):291–7.

    CAS  PubMed  Google Scholar 

  74. Baber U, Mehran R, Sharma SK, Brar S, Yu J, Suh JW, et al. Impact of the everolimus-eluting stent on stent thrombosis: a meta-analysis of 13 randomized trials. J Am Coll Cardiol. 2011;58(15):1569–77.

    Article  CAS  PubMed  Google Scholar 

  75. Manabe S, Shimokawa T, Fukui T, Fumimoto KU, Ozawa N, Seki H, et al. Coronary artery bypass surgery versus percutaneous coronary artery intervention in patients on chronic hemodialysis: does a drug-eluting stent have an impact on clinical outcome? J Card Surg. 2009;24(3):234–9.

    Article  PubMed  Google Scholar 

  76. Hiremath S. Antiplatelet medications in hemodialysis patients: a systematic review of bleeding rates. Clin J Am Soc Nephrol. 2009;4(8):1347–55.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  77. Tsai TT, Maddox TM, Roe MT, et al. Contraindicated medication use in dialysis patients undergoing percutaneous coronary intervention. JAMA. 2009;302(22):2458–64.

    Article  CAS  PubMed  Google Scholar 

  78. Alexander KP, Chen AY, Roe MT, et al. EXcess dosing of antiplatelet and antithrombin agents in the treatment of non–st-segment elevation acute coronary syndromes. JAMA. 2005;294(24):3108–16.

    Article  CAS  PubMed  Google Scholar 

  79. Liu JY, Birkmeyer NJO, Sanders JH, Morton JR, Henriques HF, Lahey SJ, et al. Risks of morbidity and mortality in dialysis patients undergoing coronary artery bypass surgery. Circulation. 2000;102(24):2973–7.

    Article  CAS  PubMed  Google Scholar 

  80. Sezai A, Nakata K, Hata M, Yoshitake I, Wakui S, Hata H, et al. Long-term results of dialysis patients with chronic kidney disease undergoing coronary artery bypass grafting. Ann Thoracic Cardiovasc Surg Off J Assoc Thorac Cardiovasc Surg Asia. 2013;19(6):441–8.

    Google Scholar 

  81. Beckermann J, Van Camp J, Li S, Wahl SK, Collins A, Herzog CA. On-pump versus off-pump coronary surgery outcomes in patients requiring dialysis: perspectives from a single center and the United States experience. J Thorac Cardiovasc Surg. 2006;131(6):1261–6.

    Article  PubMed  Google Scholar 

  82. Shroff GR, Li S, Herzog CA. Survival of patients on dialysis having off-pump versus on-pump coronary artery bypass surgery in the United States. J Thorac Cardiovasc Surg. 2010;139(5):1333–8.

    Article  PubMed  Google Scholar 

  83. Labrousse L, de Vincentiis C, Madonna F, Deville C, Roques X, Baudet E. Early and long term results of coronary artery bypass grafts in patients with dialysis dependent renal failure. Eur J Cardiothorac Surg Off J Eur Assoc Cardiothorac Surg. 1999;15(5):691–6.

    Article  CAS  Google Scholar 

  84. Castelli P, Condemi A, Munari M. Immediate and long-term results of coronary revascularization in patients undergoing chronic hemodialysis. Eur J Cardiothorac Surg. 1999;15(1):51–4.

    Article  CAS  PubMed  Google Scholar 

  85. Middleton RJ, Parfrey PS, Foley RN. Left ventricular hypertrophy in the renal patient. J Am Soc Nephrol: JASN. 2001;12(5):1079–84.

    CAS  PubMed  Google Scholar 

  86. Salem MM, Mujais S. Coronary revascularization in dialysis patients: the need for vigilance. Int J Artif Organs. 1991;14(1):7–9.

    CAS  PubMed  Google Scholar 

  87. Lockhart ME, Robbin ML, McNamara MM, Allon M. Association of pelvic arterial calcification with arteriovenous thigh graft failure in haemodialysis patients. Nephrol Dial Transplant Off Publ Eur Dial Transplant Assoc – Eur Renal Assoc. 2004;19(10):2564–9.

    Google Scholar 

  88. Crawford FA, Selby JH, Bower JD, Lehan PH. Coronary revascularization in patients maintained on chronic hemodialysis. Circulation. 1977;56(4):684–7.

    Article  PubMed  Google Scholar 

  89. Franga DL, Kratz JM, Crumbley AJ, Zellner JL, Stroud MR, Crawford FA. Early and long-term results of coronary artery bypass grafting in dialysis patients. Ann Thorac Surg. 2000;70(3):813–8. discussion 9.

    Article  CAS  PubMed  Google Scholar 

  90. Charytan DM, Li S, Liu J, Herzog CA. Risks of death and end-stage renal disease after surgical compared with percutaneous coronary revascularization in elderly patients with chronic kidney disease. Circulation. 2012;126(11 Suppl 1):S164–9.

    Article  PubMed Central  PubMed  Google Scholar 

  91. Owen CH. Coronary artery bypass grafting in patients with dialysis-dependent renal failure. Ann Thorac Surg. 1994;58(6):1729–33.

    Article  CAS  PubMed  Google Scholar 

  92. Baber U, Mehran R, Kirtane AJ, Christodoulidis G, Maehara A, Witzenbichler B, et al. TCT-486 additive and independent impact of chronic kidney disease and diabetes mellitus on high platelet reactivity and adverse events following PCI: results from the ADAPT-DES registry. J Am Coll Cardiol. 2014;64(11_S).

    Google Scholar 

  93. Farkouh ME, Domanski M, Sleeper LA, Siami FS, Dangas G, Mack M, et al. Strategies for multivessel revascularization in patients with diabetes. N Engl J Med. 2012;367(25):2375–84.

    Article  CAS  PubMed  Google Scholar 

  94. Parisi AF, Folland ED, Hartigan P. A comparison of angioplasty with medical therapy in the treatment of single-vessel coronary artery disease. Veterans Affairs ACME Investigators. N Engl J Med. 1992;326(1):10–6.

    Article  CAS  PubMed  Google Scholar 

  95. RITA-2 Trial Participants. Coronary angioplasty versus medical therapy for angina: the second Randomised Intervention Treatment of Angina (RITA-2) trial. Lancet. 1997;350(9076):461–8.

    Google Scholar 

  96. Hueb WABG, de Oliveira SA, Arie S, de Albuquerque CP, Jatene AD, Pileggi F. The Medicine, Angioplasty or Surgery Study (MASS): a prospective, randomized trial of medical therapy, balloon angioplasty or bypass surgery for single proximal left anterior descending artery stenoses. J Am Coll Cardiol. 1995;26(7):1600–5.

    Article  CAS  PubMed  Google Scholar 

  97. Yasuda K, Kasuga H, Aoyama T, Takahashi H, Toriyama T, Kawade Y, et al. Comparison of percutaneous coronary intervention with medication in the treatment of coronary artery disease in hemodialysis patients. J Am Soc Nephrol. 2006;17(8):2322–32.

    Article  PubMed  Google Scholar 

  98. Mark DB, Nelson CL, Califf RM, Harrell Jr FE, Lee KL, Jones RH, Fortin DF, Stack RS, Glower DD, Smith LR, et al. Continuing evolution of therapy for coronary artery disease. Initial results from the era of coronary angioplasty. Circulation. 1994;89(5):2015–25.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Roxana Mehran MD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Warren, J., Baber, U., Mehran, R. (2015). Invasive Management in CAD Patients with Stage 4 Renal Dysfunction or on Dialysis. In: Ambrose, J., Rodríguez, A. (eds) Controversies in Cardiology. Springer, Cham. https://doi.org/10.1007/978-3-319-20415-4_19

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-20415-4_19

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-20414-7

  • Online ISBN: 978-3-319-20415-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics