Abstract
Physiological and anatomical changes with age in the ears, nose, and throat have long been the subject of clinical interest; increasingly, they are the subject of basic and clinical investigations [1–6]. Nonetheless, the role of alterations in cells and tissues and distinctions among genetic, pathological, environmental, and interactive effects on cellular, tissue, and organ functions are still emerging [3, 7–12]. Currently, presbycusis, presbystasis, presbyosmia, presbylarynx, and presbyphonia are the terms used to denote the functionally and clinically apparent manifestations of aging changes in the ears, nose, and throat [1, 2, 13–15]. Presbyvertigo has also been proposed as a relevant term for matters of dizziness and falls in older adults though presbystasis is more commonly used [15, 16]. Notably, presbypharynx is, while being a parallel term to represent the manifestations of aging changes in the anatomy and physiology of the pharynx, not used in current literature. Instead, various uses of senescent swallowing and dysphagia predominate in the literature [17, 18].
Similar content being viewed by others
References
Belal A Jr (1975) Presbycusis: physiological or pathological. J Laryngol Otol 89:1011–1025
Belal A Jr, Glorig A (1986) Dysequilibrium of ageing (presbyastasis). J Laryngol Otol 100:1037–1041
Chen X, Thibeault SL (2008) Characteristics of age-related changes in cultured human vocal fold fibroblasts. Laryngoscope 118:1700–1704
Ju Z, Rudolph KL (2006) Telomeres and telomerase in cancer stem cells. Eur J Cancer 42:1197–1203
Thibeault SL, Glade RS, Li W (2006) Comparison of telomere length of vocal folds with different tissues: a physiological measurement of vocal senescence. J Voice 20:165–170
Walston J, Hadley EC, Ferrucci L et al (2006) Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc 54:991–1001
Agrawal Y, Carey JP, Della Santina CC, Schubert MC, Minor LB (2009) Disorders of balance and vestibular function in US adults: data from the National Health and Nutrition Examination Survey, 2001–2004. Arch Intern Med 169:938–944
Basta D, Todt I, Ernst A (2007) Characterization of age-related changes in vestibular evoked myogenic potentials. J Vestib Res 17:93–98
Sottile SY, Ling L, Cox BC, Caspary DM (2017) Impact of ageing on postsynaptic neuronal nicotinic neurotransmission in auditory thalamus. J Physiol 595:5375–5385
Gros A, Manera V, De March CA et al (2017) Olfactory disturbances in ageing with and without dementia: towards new diagnostic tools. J Laryngol Otol 131:572–579
Peyron MA, Woda A, Bourdiol P, Hennequin M (2017) Age-related changes in mastication. J Oral Rehabil 44:299–312
Reginelli A, D’Amora M, Del Vecchio L et al (2016) Videofluoroscopy and oropharyngeal manometry for evaluation of swallowing in elderly patients. Int J Surg 33(Suppl 1):S154–S158
Gates GA, Mills JH (2005) Presbycusis. Lancet 366:1111–1120
Kendall K (2007) Presbyphonia: a review. Curr Opin Otolaryngol Head Neck Surg 15:137–140
Walther LE, Westhofen M (2007) Presbyvertigo-aging of otoconia and vestibular sensory cells. J Vestib Res 17:89–92
Zalewski CK (2015) Aging of the human vestibular system. Semin Hear 36:175–196
Ney DM, Weiss JM, Kind AJ, Robbins J (2009) Senescent swallowing: impact, strategies, and interventions. Nutr Clin Pract 24:395–413
Dziewas R, Baijens L, Schindler A et al (2017) European society for swallowing disorders FEES accreditation program for neurogenic and geriatric oropharyngeal dysphagia. Dysphagia 32:725–733
Gates GA, Couropmitree NN, Myers RH (1999) Genetic associations in age-related hearing thresholds. Arch Otolaryngol Head Neck Surg 125:654–659
Fischer N, Weber B, Riechelmann H (2016) Presbycusis – age related hearing loss. Laryngorhinootologie 95:497–510
Howarth A, Shone GR (2006) Ageing and the auditory system. Postgrad Med J 82:166–171
Sha S-H, Taylor R, Forge A, Schacht J (2009) Age-related changes in the auditory system. In: Halter JB, Ouslander JG, Studenski S, High KP, Asthana S (eds) Hazzard’s geriatric medicine and gerontology. McGraw-Hill, New York
Feeney MP, Sanford CA (2004) Age effects in the human middle ear: wideband acoustical measures. J Acoust Soc Am 116:3546–3558
Wiley TL, Nondahl DM, Cruickshanks KJ, Tweed TS (2005) Five-year changes in middle ear function for older adults. J Am Acad Audiol 16:129–139
Kusunoki T, Cureoglu S, Schachern PA, Baba K, Kariya S, Paparella MM (2004) Age-related histopathologic changes in the human cochlea: a temporal bone study. Otolaryngol Head Neck Surg 131:897–903
Liu XZ, Yan D (2007) Ageing and hearing loss. J Pathol 211:188–197
Suzuki T, Nomoto Y, Nakagawa T et al (2006) Age-dependent degeneration of the stria vascularis in human cochleae. Laryngoscope 116:1846–1850
Yilmaz ST, Sennaroglu G, Sennaroglu L, Kose SK (2007) Effect of age on speech recognition in noise and on contralateral transient evoked otoacoustic emission suppression. J Laryngol Otol 121:1029–1034
Busis SN (2006) Presbycusis. In: Calhoun KH, Eibling DE (eds) Geriatric otolaryngology. Taylor and Francis, New York, pp 77–90
Tremblay K, Ross B (2007) Effects of age and age-related hearing loss on the brain. J Commun Disord 40:305–312
Caspary DM, Milbrandt JC, Helfert RH (1995) Central auditory aging: GABA changes in the inferior colliculus. Exp Gerontol 30:349–360
Gates GA, Mills D, Nam BH, D’Agostino R, Rubel EW (2002) Effects of age on the distortion product otoacoustic emission growth functions. Hear Res 163:53–60
Atcherson SR, Nagaraj NK, Kennett SE, Levisee M (2015) Overview of central auditory processing deficits in older adults. Semin Hear 36:150–161
Seligmann H, Podoshin L, Ben-David J, Fradis M, Goldsher M (1996) Drug-induced tinnitus and other hearing disorders. Drug Saf 14:198–212
Gates GA, Murphy M, Rees TS, Fraher A (2003) Screening for handicapping hearing loss in the elderly. J Fam Pract 52:56–62
Kim G, Na W, Kim G, Han W, Kim J (2016) The development and standardization of self-assessment for hearing screening of the elderly. Clin Interv Aging 11:787–795
Livshitz L, Ghanayim R, Kraus C et al (2017) Application-based hearing screening in the elderly population. Ann Otol Rhinol Laryngol 126:36–41
Deshpande N, Patla AE (2007) Visual-vestibular interaction during goal directed locomotion: effects of aging and blurring vision. Exp Brain Res 176:43–53
Lee TM, Leung AW, Fox PT, Gao JH, Chan CC (2008) Age-related differences in neural activities during risk taking as revealed by functional MRI. Soc Cogn Affect Neurosci 3:7–15
Su HC, Huang TW, Young YH, Cheng PW (2004) Aging effect on vestibular evoked myogenic potential. Otol Neurotol 25:977–980
Straumann D (2016) Bedside examination. Handb Clin Neurol 137:91–101
Ekvall Hansson E, Mansson NO, Hakansson A (2005) Benign paroxysmal positional vertigo among elderly patients in primary health care. Gerontology 51:386–389
Moody M, Ross AT (2006) Rhinoplasty in the aging patient. Facial Plast Surg 22:112–119
Whitney SL, Morris L (2006) Multisensory impairment in older adults: evaluation and intervention. Taylor and Francis, New York
Lindemann J, Sannwald D, Wiesmiller K (2008) Age-related changes in intranasal air conditioning in the elderly. Laryngoscope 118:1472–1475
Sahin-Yilmaz AA, Corey JP (2007) Rhinitis in the elderly. Clin Allergy Immunol 19:209–219
Chadwick SJ (2006) Allergic rhinitis in the elderly. In: Calhoun KH, Eibling DE (eds) Geriatric otolaryngology. Taylor and Francis, New York, pp 213–224
Lafreniere D, Mann N (2009) Anosmia: loss of smell in the elderly. Otolaryngol Clin N Am 42:123–131, x
Rawson NE (2006) Olfactory loss in aging. Sci Aging Knowl Environ 2006:pe6
Schiffman SS, Graham BG (2000) Taste and smell perception affect appetite and immunity in the elderly. Eur J Clin Nutr 54(Suppl 3):S54–S63
Wilson RS, Schneider JA, Arnold SE, Tang Y, Boyle PA, Bennett DA (2007) Olfactory identification and incidence of mild cognitive impairment in older age. Arch Gen Psychiatry 64:802–808
Attems J, Lintner F, Jellinger KA (2005) Olfactory involvement in aging and Alzheimer’s disease: an autopsy study. J Alzheimers Dis 7:149–157; discussion 173-180
Boesveldt S, de Muinck Keizer RJ, Wolters E, Berendse HW (2009) Odor recognition memory is not independently impaired in Parkinson’s disease. J Neural Transm (Vienna) 116:575–578
Mirza N (2006) Taste changes in the elderly. In: Calhoun KH, Eibling DE (eds) Geriatric otolaryngology. Taylor and Francis, New York, pp 195–203
Hur GY, Lee JH, Park HS (2017) Allergen immunotherapy for the treatment of respiratory allergies in the elderly. Curr Opin Allergy Clin Immunol 17:304–308
Sataloff RT, Linville SE (2006) The effects of age on voice. In: Calhoun KH, Eibling DE (eds) Geratric otolaryngology. Taylor and Francis, New York, pp 349–364
German RZ, Palmer JB (2006) Part 1 Oral cavity, pharynx and esophagus. In: Goyal R, Shaker R (eds) GI motility online. Nature Publishing, New York. http://www.nature.com/gimo/contents/pt1/full/gimo5.html – Related content. Accessed 5 Aug 2017
Kawamura O, Easterling C, Aslam M, Rittmann T, Hofmann C, Shaker R (2004) Laryngo-upper esophageal sphincter contractile reflex in humans deteriorates with age. Gastroenterology 127:57–64
Kersing W, Jennekens FG (2004) Age-related changes in human thyroarytenoid muscles: a histological and histochemical study. Eur Arch Otorhinolaryngol 261:386–392
Pontes P, Yamasaki R, Behlau M (2006) Morphological and functional aspects of the senile larynx. Folia Phoniatr Logop 58:151–158
Chalmers JM, Ettinger RL (2008) Public health issues in geriatric dentistry in the United States. Dent Clin N Am 52:423–446, vii-viii
Turner MD, Ship JA (2007) Dry mouth and its effects on the oral health of elderly people. J Am Dent Assoc 138(Suppl):15S–20S
Cabre M, Serra-Prat M, Palomera E, Almirall J, Pallares R, Clave P (2010) Prevalence and prognostic implications of dysphagia in elderly patients with pneumonia. Age Ageing 39:39–45
Percival RS (2009) Changes in oral microflora and host defences with advanced age. Microbiol Aging 131–152. http://www.springerlink.com/content/g3ul5987p4307264/about/
Fukunaga A, Uematsu H, Sugimoto K (2005) Influences of aging on taste perception and oral somatic sensation. J Gerontol A Biol Sci Med Sci 60:109–113
Martin-Harris B, Brodsky MB, Michel Y, Ford CL, Walters B, Heffner J (2005) Breathing and swallowing dynamics across the adult lifespan. Arch Otolaryngol Head Neck Surg 131:762–770
Hall KE (2009) Effect of aging on gastrointestinal function, chapter 89. In: Halter J, Ouslander JG, Tinetti ME, Studenski S, High KP, Asthana S (eds) Hazzard’s geriatric medicine and gerontology, 6th edn. McGraw-Hill, New York
Johns MM 3rd, Arviso LC, Ramadan F (2011) Challenges and opportunities in the management of the aging voice. Otolaryngol Head Neck Surg 145:1–6
Ortega O, Martin A, Clave P (2017) Diagnosis and management of oropharyngeal dysphagia among older persons, state of the art. J Am Med Dir Assoc 18:576–582
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this entry
Cite this entry
Chalian, A.A., Rajasekaran, K., Kagan, S.H. (2019). Anatomic and Physiologic Changes in the Ears, Nose, and Throat. In: Rosenthal, R., Zenilman, M., Katlic, M. (eds) Principles and Practice of Geriatric Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-20317-1_35-1
Download citation
DOI: https://doi.org/10.1007/978-3-319-20317-1_35-1
Received:
Accepted:
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-20317-1
Online ISBN: 978-3-319-20317-1
eBook Packages: Springer Reference MedicineReference Module Medicine