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Sleep Features and Underlying Mechanisms Related to Epilepsy and Its Long Term Monitoring

  • Chapter
Cyberphysical Systems for Epilepsy and Related Brain Disorders

Abstract

The reciprocal relationship between sleep and epilepsy has been recognized since antiquity. The exact mechanisms underlying the precise nature of this relation though, remain unclear even today. The scope of this chapter is to describe the basic neurophysiologic mechanisms underlying sleep and its relation to the interictal epileptiform discharges and epileptic seizures. Furthermore, the theoretical background of the mechanisms involved in the interaction of sleep and epilepsy are discussed especially the effects that sleep mechanisms have on altering brain synchrony and excitability, which consist the hallmark of epileptiform activity in the brain. Finally, aspects of the open problems in polysomnographic long term monitoring of epilepsy are examined, which the ARMOR approached aimed to address.

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Authors and Affiliations

  1. Neurophysiology Unit, Department of Physiology, Medical School, University of Patras, Patras, Greece

    Evangelia Giourou, Alkistis Stavropoulou-Deli, Konstantinos Theofilatos & George K. Kostopoulos

  2. Laboratory for Human Brain Dynamics, AAI Scientific Cultural Services Ltd., Nicosia, Cyprus

    Andreas A. Ioannides

  3. Department of Clinical Neurophysiology and Epilepsy, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

    Michalis Koutroumanidis

  4. Department of Academic Neurosciences, Kings College London, London, UK

    Michalis Koutroumanidis

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  1. Evangelia Giourou
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  3. Konstantinos Theofilatos
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  4. George K. Kostopoulos
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  5. Andreas A. Ioannides
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Correspondence to George K. Kostopoulos .

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    Nikolaos S. Voros

  2. Computer & Informatics Engineering Department, Technological Educational Institute of Western Greece, Antirio, Greece

    Christos P. Antonopoulos

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Giourou, E., Stavropoulou-Deli, A., Theofilatos, K., Kostopoulos, G.K., Ioannides, A.A., Koutroumanidis, M. (2015). Sleep Features and Underlying Mechanisms Related to Epilepsy and Its Long Term Monitoring. In: Voros, N., Antonopoulos, C. (eds) Cyberphysical Systems for Epilepsy and Related Brain Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-20049-1_3

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